PDB entry 6s7h

View 6s7h on RCSB PDB site
Description: human cd73 (5'-nucleotidase) in complex with psb12489 (an aopcp derivative) in the closed state
Deposited on 2019-07-04, released 2020-07-22
The last revision was dated 2020-07-22, with a file datestamp of 2020-07-17.
Experiment type: XRAY
Resolution: 1.85 Å
R-factor: N/A
AEROSPACI score: 0.43 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: 5'-nucleotidase
    Species: Homo sapiens [TaxId:9606]
    Gene: NT5E, NT5, NTE
    Database cross-references and differences (RAF-indexed):
    • Uniprot P21589 (1-523)
      • initiating methionine (0)
      • engineered mutation (27)
      • engineered mutation (285)
      • engineered mutation (307)
      • engineered mutation (377)
      • expression tag (524-525)
  • Heterogens: KYW, ZN, CA, HOH

PDB Chain Sequences:
This PDB entry is not classified in SCOPe 2.08, so the chain sequences below are not included in the ASTRAL sequence sets.

  • Chain 'A':
    Sequence, based on SEQRES records:
    >6s7hA (A:)
mweltilhtndvhsrleqtsedsskcvdasrcmggvarlftkvqqirraepnvllldagd
qyqgtiwftvykgaevahfmnalrydamalgnhefdngvegliepllkeakfpilsanik
akgplasqisglylpykvlpvgdevvgivgytsketpflsnpgtnlvfedeitalqpevd
klktlnvnkiialghsgfemdkliaqkvrgvdvvvgghsntflytgnppskevpagkypf
ivtsddgrkvpvvqayafgkylgylkiefdergnvisshgnpilldssipedpsikadin
kwriklddystqelgktivyldgssqscrfrecnmgnlicdaminnnlrhtdemfwnhvs
mcilngggirspiderndgtitwenlaavlpfggtfdlvqlkgstlkkafehsvhrygqs
tgeflqvggihvvydlsrkpgdrvvkldvlctkcrvpsydplkmdevykvilpnflangg
dgfqmikdellrhdsgdqdinvvstyiskmkviypavegrikfslehhhhhh

    Sequence, based on observed residues (ATOM records):
    >6s7hA (A:)
mweltilhtndvhsrleqtsedsskcvdasrcmggvarlftkvqqirraepnvllldagd
qyqgtiwftvykgaevahfmnalrydamalgnhefdngvegliepllkeakfpilsanik
akgplasqisglylpykvlpvgdevvgivgytsketpflsnpgtnlvfedeitalqpevd
klktlnvnkiialghsgfemdkliaqkvrgvdvvvgghsntflytgnppskevpagkypf
ivtsddgrkvpvvqayafgkylgylkiefdergnvisshgnpilldssipedpsikadin
kwriklddystqelgktivyldgssqscrfrecnmgnlicdaminnnlrnhvsmcilngg
girspiderndgtitwenlaavlpfggtfdlvqlkgstlkkafehsvhrygqstgeflqv
ggihvvydlsrkpgdrvvkldvlctkcrvpsydplkmdevykvilpnflanggdgfqmik
dellrhdsgdqdinvvstyiskmkviypavegrikfsle