PDB entry 6s62

View 6s62 on RCSB PDB site
Description: Crystal structure of 2-methylcitrate dehydratase (PrpD) from Pseudomonas aeruginosa in apo form.
Class: isomerase
Keywords: 2-methlycitrate dehydratase, MmgE/PrpD, propionate metabolism, ISOMERASE
Deposited on 2019-07-02, released 2020-10-14
The last revision prior to the SCOPe 2.08 freeze date was dated 2020-10-14, with a file datestamp of 2020-10-09.
Experiment type: XRAY
Resolution: 2.36 Å
R-factor: N/A
AEROSPACI score: 0.3 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Propionate catabolic protein PrpD
    Species: Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1) [TaxId:208964]
    Gene: prpD, PA0792
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d6s62a_
  • Chain 'B':
    Compound: Propionate catabolic protein PrpD
    Species: Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1) [TaxId:208964]
    Gene: prpD, PA0792
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d6s62b_
  • Chain 'C':
    Compound: Propionate catabolic protein PrpD
    Species: Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1) [TaxId:208964]
    Gene: prpD, PA0792
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d6s62c_
  • Chain 'D':
    Compound: Propionate catabolic protein PrpD
    Species: Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1) [TaxId:208964]
    Gene: prpD, PA0792
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d6s62d_
  • Chain 'E':
    Compound: Propionate catabolic protein PrpD
    Species: Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1) [TaxId:208964]
    Gene: prpD, PA0792
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d6s62e_
  • Chain 'F':
    Compound: Propionate catabolic protein PrpD
    Species: Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1) [TaxId:208964]
    Gene: prpD, PA0792
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d6s62f_
  • Heterogens: HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >6s62A (A:)
msanvdlnqrpdydavlqdiadyvldyridstealdtarnclmdtlgcgllalrfpectk
hlgplvegtlvphgarvpgtsfrldpvkaawdigcivrwldyndtwlaaewghpsdnlgg
ilavadhlsqkrlangeaplsmrqvleamimaheiqgvialensfnrvgldhvllvkvas
tavcaklmgadreqllaalshafvdgqalrtyrhapnagsrkswaagdatsrgvrladia
lrgemgipgvlsapqwgfydvlfshtskdlatkpedkrrfsfpqgygsyvmenvlfkisf
paefhaqtaaeaavrlhplvkdrlqrisrivitthesairiiskvgplanpadrdhclqy
mtavplifgdlvaehyedafhaahplidrlrekmeiveeprysreyleadkrsianavev
ffddgsstgqvaveyplghrrrraegipllqekfkanlatrfppqrcqrifdlcshqasl
eatpvnrfmdllai

    Sequence, based on observed residues (ATOM records): (download) 
    >6s62A (A:)
rpdydavlqdiadyvldyridstealdtarnclmdtlgcgllalrfpectkhlgplvegt
lvphgarvpgtsfrldpvkaawdigcivrwldyndtwlaaewghpsdnlggilavadhls
qkrlangeaplsmrqvleamimaheiqgvialensfnrvgldhvllvkvastavcaklmg
adreqllaalshafvdgqalrtyrhapnagsrkswaagdatsrgvrladialrgemgipg
vlsapqwgfydvlfshtskdlatkpedkrrfsfpqgygsyvmenvlfkisfpaefhaqta
aeaavrlhplvkdrlqrisrivitthesairiiskvgplanpadrdhclqymtavplifg
dlvaehyedafhaahplidrlrekmeiveeprysreyleadkrsianavevffddgsstg
qvaveyplghrrrraegipllqekfkanlatrfppqrcqrifdlcshqasleatpvnrfm
dllai

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >6s62B (B:)
msanvdlnqrpdydavlqdiadyvldyridstealdtarnclmdtlgcgllalrfpectk
hlgplvegtlvphgarvpgtsfrldpvkaawdigcivrwldyndtwlaaewghpsdnlgg
ilavadhlsqkrlangeaplsmrqvleamimaheiqgvialensfnrvgldhvllvkvas
tavcaklmgadreqllaalshafvdgqalrtyrhapnagsrkswaagdatsrgvrladia
lrgemgipgvlsapqwgfydvlfshtskdlatkpedkrrfsfpqgygsyvmenvlfkisf
paefhaqtaaeaavrlhplvkdrlqrisrivitthesairiiskvgplanpadrdhclqy
mtavplifgdlvaehyedafhaahplidrlrekmeiveeprysreyleadkrsianavev
ffddgsstgqvaveyplghrrrraegipllqekfkanlatrfppqrcqrifdlcshqasl
eatpvnrfmdllai

    Sequence, based on observed residues (ATOM records): (download) 
    >6s62B (B:)
pdydavlqdiadyvldyridstealdtarnclmdtlgcgllalrfpectkhlgplvegtl
vphgarvpgtsfrldpvkaawdigcivrwldyndtwlaaewghpsdnlggilavadhlsq
krlangeaplsmrqvleamimaheiqgvialensfnrvgldhvllvkvastavcaklmga
dreqllaalshafvdgqalrtyrhapnagsrkswaagdatsrgvrladialrgemgipgv
lsapqwgfydvlfshtskdlatkpedkrrfsfpqgygsyvmenvlfkisfpaefhaqtaa
eaavrlhplvkdrlqrisrivitthesairiiskvgplanpadrdhclqymtavplifgd
lvaehyedafhaahplidrlrekmeiveeprysreyleadkrsianavevffddgsstgq
vaveyplghrrrraegipllqekfkanlatrfppqrcqrifdlcshqasleatpvnrfmd
llai

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >6s62C (C:)
msanvdlnqrpdydavlqdiadyvldyridstealdtarnclmdtlgcgllalrfpectk
hlgplvegtlvphgarvpgtsfrldpvkaawdigcivrwldyndtwlaaewghpsdnlgg
ilavadhlsqkrlangeaplsmrqvleamimaheiqgvialensfnrvgldhvllvkvas
tavcaklmgadreqllaalshafvdgqalrtyrhapnagsrkswaagdatsrgvrladia
lrgemgipgvlsapqwgfydvlfshtskdlatkpedkrrfsfpqgygsyvmenvlfkisf
paefhaqtaaeaavrlhplvkdrlqrisrivitthesairiiskvgplanpadrdhclqy
mtavplifgdlvaehyedafhaahplidrlrekmeiveeprysreyleadkrsianavev
ffddgsstgqvaveyplghrrrraegipllqekfkanlatrfppqrcqrifdlcshqasl
eatpvnrfmdllai

    Sequence, based on observed residues (ATOM records): (download) 
    >6s62C (C:)
pdydavlqdiadyvldyridstealdtarnclmdtlgcgllalrfpectkhlgplvegtl
vphgarvpgtsfrldpvkaawdigcivrwldyndtwlaaewghpsdnlggilavadhlsq
krlangeaplsmrqvleamimaheiqgvialensfnrvgldhvllvkvastavcaklmga
dreqllaalshafvdgqalrtyrhapnagsrkswaagdatsrgvrladialrgemgipgv
lsapqwgfydvlfshtskdlatkpedkrrfsfpqgygsyvmenvlfkisfpaefhaqtaa
eaavrlhplvkdrlqrisrivitthesairiiskvgplanpadrdhclqymtavplifgd
lvaehyedafhaahplidrlrekmeiveeprysreyleadkrsianavevffddgsstgq
vaveyplghrrrraegipllqekfkanlatrfppqrcqrifdlcshqasleatpvnrfmd
lla

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >6s62D (D:)
msanvdlnqrpdydavlqdiadyvldyridstealdtarnclmdtlgcgllalrfpectk
hlgplvegtlvphgarvpgtsfrldpvkaawdigcivrwldyndtwlaaewghpsdnlgg
ilavadhlsqkrlangeaplsmrqvleamimaheiqgvialensfnrvgldhvllvkvas
tavcaklmgadreqllaalshafvdgqalrtyrhapnagsrkswaagdatsrgvrladia
lrgemgipgvlsapqwgfydvlfshtskdlatkpedkrrfsfpqgygsyvmenvlfkisf
paefhaqtaaeaavrlhplvkdrlqrisrivitthesairiiskvgplanpadrdhclqy
mtavplifgdlvaehyedafhaahplidrlrekmeiveeprysreyleadkrsianavev
ffddgsstgqvaveyplghrrrraegipllqekfkanlatrfppqrcqrifdlcshqasl
eatpvnrfmdllai

    Sequence, based on observed residues (ATOM records): (download) 
    >6s62D (D:)
rpdydavlqdiadyvldyridstealdtarnclmdtlgcgllalrfpectkhlgplvegt
lvphgarvpgtsfrldpvkaawdigcivrwldyndtwlaaewghpsdnlggilavadhls
qkrlangeaplsmrqvleamimaheiqgvialensfnrvgldhvllvkvastavcaklmg
adreqllaalshafvdgqalrtyrhapnagsrkswaagdatsrgvrladialrgemgipg
vlsapqwgfydvlfshtskdlatkpedkrrfsfpqgygsyvmenvlfkisfpaefhaqta
aeaavrlhplvkdrlqrisrivitthesairiiskvgplanpadrdhclqymtavplifg
dlvaehyedafhaahplidrlrekmeiveeprysreyleadkrsianavevffddgsstg
qvaveyplghrrrraegipllqekfkanlatrfppqrcqrifdlcshqasleatpvnrfm
dlla

  • Chain 'E':
    Sequence, based on SEQRES records: (download) 
    >6s62E (E:)
msanvdlnqrpdydavlqdiadyvldyridstealdtarnclmdtlgcgllalrfpectk
hlgplvegtlvphgarvpgtsfrldpvkaawdigcivrwldyndtwlaaewghpsdnlgg
ilavadhlsqkrlangeaplsmrqvleamimaheiqgvialensfnrvgldhvllvkvas
tavcaklmgadreqllaalshafvdgqalrtyrhapnagsrkswaagdatsrgvrladia
lrgemgipgvlsapqwgfydvlfshtskdlatkpedkrrfsfpqgygsyvmenvlfkisf
paefhaqtaaeaavrlhplvkdrlqrisrivitthesairiiskvgplanpadrdhclqy
mtavplifgdlvaehyedafhaahplidrlrekmeiveeprysreyleadkrsianavev
ffddgsstgqvaveyplghrrrraegipllqekfkanlatrfppqrcqrifdlcshqasl
eatpvnrfmdllai

    Sequence, based on observed residues (ATOM records): (download) 
    >6s62E (E:)
rpdydavlqdiadyvldyridstealdtarnclmdtlgcgllalrfpectkhlgplvegt
lvphgarvpgtsfrldpvkaawdigcivrwldyndtwlaaewghpsdnlggilavadhls
qkrlangeaplsmrqvleamimaheiqgvialensfnrvgldhvllvkvastavcaklmg
adreqllaalshafvdgqalrtyrhapnagsrkswaagdatsrgvrladialrgemgipg
vlsapqwgfydvlfshtskdlatkpedkrrfsfpqgygsyvmenvlfkisfpaefhaqta
aeaavrlhplvkdrlqrisrivitthesairiiskvgplanpadrdhclqymtavplifg
dlvaehyedafhaahplidrlrekmeiveeprysreyleadkrsianavevffddgsstg
qvaveyplghrrrraegipllqekfkanlatrfppqrcqrifdlcshqasleatpvnrfm
dllai

  • Chain 'F':
    Sequence, based on SEQRES records: (download) 
    >6s62F (F:)
msanvdlnqrpdydavlqdiadyvldyridstealdtarnclmdtlgcgllalrfpectk
hlgplvegtlvphgarvpgtsfrldpvkaawdigcivrwldyndtwlaaewghpsdnlgg
ilavadhlsqkrlangeaplsmrqvleamimaheiqgvialensfnrvgldhvllvkvas
tavcaklmgadreqllaalshafvdgqalrtyrhapnagsrkswaagdatsrgvrladia
lrgemgipgvlsapqwgfydvlfshtskdlatkpedkrrfsfpqgygsyvmenvlfkisf
paefhaqtaaeaavrlhplvkdrlqrisrivitthesairiiskvgplanpadrdhclqy
mtavplifgdlvaehyedafhaahplidrlrekmeiveeprysreyleadkrsianavev
ffddgsstgqvaveyplghrrrraegipllqekfkanlatrfppqrcqrifdlcshqasl
eatpvnrfmdllai

    Sequence, based on observed residues (ATOM records): (download) 
    >6s62F (F:)
rpdydavlqdiadyvldyridstealdtarnclmdtlgcgllalrfpectkhlgplvegt
lvphgarvpgtsfrldpvkaawdigcivrwldyndtwlaaewghpsdnlggilavadhls
qkrlangeaplsmrqvleamimaheiqgvialensfnrvgldhvllvkvastavcaklmg
adreqllaalshafvdgqalrtyrhapnagsrkswaagdatsrgvrladialrgemgipg
vlsapqwgfydvlfshtskdlatkpedkrrfsfpqgygsyvmenvlfkisfpaefhaqta
aeaavrlhplvkdrlqrisrivitthesairiiskvgplanpadrdhclqymtavplifg
dlvaehyedafhaahplidrlrekmeiveeprysreyleadkrsianavevffddgsstg
qvaveyplghrrrraegipllqekfkanlatrfppqrcqrifdlcshqasleatpvnrfm
dllai