PDB entry 6s4u

View 6s4u on RCSB PDB site
Description: LXRbeta ligand binding domain in comlpex with small molecule inhibitors
Class: nuclear protein
Keywords: liver X receptor beta LXRb LXR beta Nuclear hormone receptor receptor ligand binding domain, nuclear protein
Deposited on 2019-06-28, released 2019-11-27
The last revision prior to the SCOPe 2.08 freeze date was dated 2019-12-18, with a file datestamp of 2019-12-13.
Experiment type: XRAY
Resolution: 2.81 Å
R-factor: N/A
AEROSPACI score: 0.17 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: oxysterols receptor lxr-beta
    Species: Homo sapiens [TaxId:9606]
    Gene: NR1H2, LXRB, NER, UNR
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d6s4ua_
  • Chain 'B':
    Compound: oxysterols receptor lxr-beta
    Species: Homo sapiens [TaxId:9606]
    Gene: NR1H2, LXRB, NER, UNR
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d6s4ub_
  • Chain 'C':
    Compound: oxysterols receptor lxr-beta
    Species: Homo sapiens [TaxId:9606]
    Gene: NR1H2, LXRB, NER, UNR
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d6s4uc_
  • Heterogens: KVK, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >6s4uA (A:)
gvqltaaqelmiqqlvaaqlqcnkrsfsdqpkvtpwplgadpqsrdarqqrfahftelai
isvqeivdfakqvpgflqlgredqiallkastieimlletarrynhetecitflkdftys
kddfhraglqvefinpifefsramrrlglddaeyalliainifsadrpnvqepgrvealq
qpyveallsytrikrpqdqlrfprmlmklvslrtlssvhseqvfalrlqdkklppllsei
wdvhe

    Sequence, based on observed residues (ATOM records): (download) 
    >6s4uA (A:)
qltaaqelmiqqlvaaqlqcnkrsfsdqpkvtpwpqsrdarqqrfahftelaiisvqeiv
dfakqvpgflqlgredqiallkastieimlletarrynhetecitflkdftyskddfhra
glqvefinpifefsramrrlglddaeyalliainifsadrpnvqepgrvealqqpyveal
lsytrikrpqdqlrfprmlmklvslrtlssvhseqvfalrlqdkklppllseiwdv

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >6s4uB (B:)
gvqltaaqelmiqqlvaaqlqcnkrsfsdqpkvtpwplgadpqsrdarqqrfahftelai
isvqeivdfakqvpgflqlgredqiallkastieimlletarrynhetecitflkdftys
kddfhraglqvefinpifefsramrrlglddaeyalliainifsadrpnvqepgrvealq
qpyveallsytrikrpqdqlrfprmlmklvslrtlssvhseqvfalrlqdkklppllsei
wdvhe

    Sequence, based on observed residues (ATOM records): (download) 
    >6s4uB (B:)
qltaaqelmiqqlvaaqlqcnkrsfsdqpkvtpwpdarqqrfahftelaiisvqeivdfa
kqvpgflqlgredqiallkastieimlletarrynhetecitflkdftyskddfhraglq
vefinpifefsramrrlglddaeyalliainifsadrpnvqepgrvealqqpyveallsy
trikrpqdqlrfprmlmklvslrtlssvhseqvfalrlqdkklppllseiwdv

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >6s4uC (C:)
gvqltaaqelmiqqlvaaqlqcnkrsfsdqpkvtpwplgadpqsrdarqqrfahftelai
isvqeivdfakqvpgflqlgredqiallkastieimlletarrynhetecitflkdftys
kddfhraglqvefinpifefsramrrlglddaeyalliainifsadrpnvqepgrvealq
qpyveallsytrikrpqdqlrfprmlmklvslrtlssvhseqvfalrlqdkklppllsei
wdvhe

    Sequence, based on observed residues (ATOM records): (download) 
    >6s4uC (C:)
vqltaaqelmiqqlvaaqlqcnkrsfpkvtpwpqsrdarqqrfahftelaiisvqeivdf
akqvpgflqlgredqiallkastieimlletarrynhetecitflkdftyskddfhragl
qvefinpifefsramrrlglddaeyalliainifsadrpnvqepgrvealqqpyvealls
ytrikrpqdqlrfprmlmklvslrtlssvhseqvfalrlqdkklppllseiwdv