PDB entry 6rv2

View 6rv2 on RCSB PDB site
Description: crystal structure of the human two pore domain potassium ion channel task-1 (k2p3.1) in a closed conformation
Deposited on 2019-05-30, released 2019-08-07
The last revision was dated 2020-07-22, with a file datestamp of 2020-07-17.
Experiment type: XRAY
Resolution: 3 Å
R-factor: N/A
AEROSPACI score: 0.24 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Potassium channel subfamily K member 3
    Species: Homo sapiens [TaxId:9606]
    Gene: KCNK3, TASK, TASK1
    Database cross-references and differences (RAF-indexed):
  • Chain 'B':
    Compound: Potassium channel subfamily K member 3
    Species: Homo sapiens [TaxId:9606]
    Gene: KCNK3, TASK, TASK1
    Database cross-references and differences (RAF-indexed):
    • Uniprot O14649 (0-258)
      • expression tag (259-260)
  • Chain 'C':
    Compound: Potassium channel subfamily K member 3
    Species: Homo sapiens [TaxId:9606]
    Gene: KCNK3, TASK, TASK1
    Database cross-references and differences (RAF-indexed):
  • Chain 'D':
    Compound: Potassium channel subfamily K member 3
    Species: Homo sapiens [TaxId:9606]
    Gene: KCNK3, TASK, TASK1
    Database cross-references and differences (RAF-indexed):
    • Uniprot O14649 (0-258)
      • expression tag (259-260)
  • Heterogens: K, Y01, DMU, PC1, HOH

PDB Chain Sequences:
This PDB entry is not classified in SCOPe 2.08, so the chain sequences below are not included in the ASTRAL sequence sets.

  • Chain 'A':
    Sequence, based on SEQRES records:
    >6rv2A (A:)
mkrqnvrtlalivctftyllvgaavfdalesepelierqrlelrqqelrarynlsqggye
elervvlrlkphkagvqwrfagsfyfaitvittigyghaapstdggkvfcmfyallgipl
tlvmfqslgerintlvryllhrakkglgmrradvsmanmvligffscistlcigaaafsh
yehwtffqayyycfitlttigfgdyvalqkdqalqtqpqyvafsfvyiltgltvigafln
lvvlrfmtmnaedekrdaenlyfq

    Sequence, based on observed residues (ATOM records):
    >6rv2A (A:)
mkrqnvrtlalivctftyllvgaavfdalesepelierqrlelrqqelrarynlsqggye
elervvlrlkphkagvqwrfagsfyfaitvittigyghaapstdggkvfcmfyallgipl
tlvmfqslgerintlvryllhrakkglgadvsmanmvligffscistlcigaaafshyeh
wtffqayyycfitlttigfgdyvalqkdqalqtqpqyvafsfvyiltgltvigaflnlvv
lrfmtmnaedekrd

  • Chain 'B':
    Sequence, based on SEQRES records:
    >6rv2B (B:)
mkrqnvrtlalivctftyllvgaavfdalesepelierqrlelrqqelrarynlsqggye
elervvlrlkphkagvqwrfagsfyfaitvittigyghaapstdggkvfcmfyallgipl
tlvmfqslgerintlvryllhrakkglgmrradvsmanmvligffscistlcigaaafsh
yehwtffqayyycfitlttigfgdyvalqkdqalqtqpqyvafsfvyiltgltvigafln
lvvlrfmtmnaedekrdaenlyfq

    Sequence, based on observed residues (ATOM records):
    >6rv2B (B:)
mkrqnvrtlalivctftyllvgaavfdalesepelierqrlelrqqelrarynlsqggye
elervvlrlkphkagvqwrfagsfyfaitvittigyghaapstdggkvfcmfyallgipl
tlvmfqslgerintlvryllhrakkglgadvsmanmvligffscistlcigaaafshyeh
wtffqayyycfitlttigfgdyvalqkdqalqtqpqyvafsfvyiltgltvigaflnlvv
lrfmtmnaedekrdaenl

  • Chain 'C':
    Sequence, based on SEQRES records:
    >6rv2C (C:)
mkrqnvrtlalivctftyllvgaavfdalesepelierqrlelrqqelrarynlsqggye
elervvlrlkphkagvqwrfagsfyfaitvittigyghaapstdggkvfcmfyallgipl
tlvmfqslgerintlvryllhrakkglgmrradvsmanmvligffscistlcigaaafsh
yehwtffqayyycfitlttigfgdyvalqkdqalqtqpqyvafsfvyiltgltvigafln
lvvlrfmtmnaedekrdaenlyfq

    Sequence, based on observed residues (ATOM records):
    >6rv2C (C:)
mkrqnvrtlalivctftyllvgaavfdalesepelierqrlelrqqelrarynlsqggye
elervvlrlkphkagvqwrfagsfyfaitvittigyghaapstdggkvfcmfyallgipl
tlvmfqslgerintlvryllhrakkglgmrradvsmanmvligffscistlcigaaafsh
yehwtffqayyycfitlttigfgdyvalqkdqalqtqpqyvafsfvyiltgltvigafln
lvvlrfmtmnaedekrd

  • Chain 'D':
    Sequence, based on SEQRES records:
    >6rv2D (D:)
mkrqnvrtlalivctftyllvgaavfdalesepelierqrlelrqqelrarynlsqggye
elervvlrlkphkagvqwrfagsfyfaitvittigyghaapstdggkvfcmfyallgipl
tlvmfqslgerintlvryllhrakkglgmrradvsmanmvligffscistlcigaaafsh
yehwtffqayyycfitlttigfgdyvalqkdqalqtqpqyvafsfvyiltgltvigafln
lvvlrfmtmnaedekrdaenlyfq

    Sequence, based on observed residues (ATOM records):
    >6rv2D (D:)
mkrqnvrtlalivctftyllvgaavfdalesepelierqrlelrqqelrarynlsqggye
elervvlrlkphkagvqwrfagsfyfaitvittigyghaapstdggkvfcmfyallgipl
tlvmfqslgerintlvryllhrakkglgmrradvsmanmvligffscistlcigaaafsh
yehwtffqayyycfitlttigfgdyvalqkdqalqtqpqyvafsfvyiltgltvigafln
lvvlrfmtmnaedekrdaenl