PDB entry 6rod

View 6rod on RCSB PDB site
Description: Alpha-1-antitrypsin (Ser36Arg/Glu78Arg/Glu266Arg) in the native conformation
Class: protein binding
Keywords: Antitrypsin, protease inhibitor, serpin, mutant, deficiency, PROTEIN BINDING, breach region
Deposited on 2019-05-11, released 2020-06-03
The last revision prior to the SCOPe 2.08 freeze date was dated 2020-06-03, with a file datestamp of 2020-05-29.
Experiment type: XRAY
Resolution: 1.85 Å
R-factor: N/A
AEROSPACI score: 0.35 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: alpha-1-antitrypsin
    Species: Homo sapiens [TaxId:9606]
    Gene: SERPINA1, AAT, PI, PRO0684, PRO2209
    Database cross-references and differences (RAF-indexed):
    • Uniprot P01009 (Start-403)
      • engineered mutation (45)
      • engineered mutation (87)
      • engineered mutation (275)
    Domains in SCOPe 2.08: d6roda_
  • Heterogens: HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >6rodA (A:)
mrgshhhhhhtdpqgdaaqktdtshhdqdhptfnkitpnlaefafrlyrqlahqsnstni
ffspvsiatafamlslgtkadthdeilrglnfnlteipeaqihegfqellrtlnqpdsql
qlttgnglflseglklvdkfledvkklyhseaftvnfgdteeakkqindyvekgtqgkiv
dlvkeldrdtvfalvnyiffkgkwerpfevkdteeedfhvdqvttvkvpmmkrlgmfniq
hckklsswvllmkylgnataifflpdegklqhlenrlthdiitkflenedrrsaslhlpk
lsitgtydlksvlgqlgitkvfsngadlsgvteeaplklskavhkavltidekgteaaga
mfleaipmsippevkfnkpfvflmieqntksplfmgkvvnptqk

    Sequence, based on observed residues (ATOM records): (download) 
    >6rodA (A:)
fnkitpnlaefafrlyrqlahqsnstniffspvsiatafamlslgtkadthdeilrglnf
nlteipeaqihegfqellrtlnqpdsqlqlttgnglflseglklvdkfledvkklyhsea
ftvnfgdteeakkqindyvekgtqgkivdlvkeldrdtvfalvnyiffkgkwerpfevkd
teeedfhvdqvttvkvpmmkrlgmfniqhckklsswvllmkylgnataifflpdegklqh
lenrlthdiitkflenedrrsaslhlpklsitgtydlksvlgqlgitkvfsngadlsgvt
eeaplklskavhkavltidekgtmfleaipmsippevkfnkpfvflmieqntksplfmgk
vvnptqk