PDB entry 6rn8

View 6rn8 on RCSB PDB site
Description: RIP2 Kinase Catalytic Domain complex with 2(4[(1,3benzothiazol5yl)amino]6(2methylpropane2sulfonyl)quinazolin7yl)oxy)ethyl phosphate
Class: transferase
Keywords: Kinase, Structure Based drug discovery, TRANSFERASE
Deposited on 2019-05-08, released 2019-07-17
The last revision prior to the SCOPe 2.08 freeze date was dated 2019-08-07, with a file datestamp of 2019-08-02.
Experiment type: XRAY
Resolution: 2.69 Å
R-factor: N/A
AEROSPACI score: 0.18 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: receptor-interacting serine/threonine-protein kinase 2
    Species: Homo sapiens [TaxId:9606]
    Gene: RIPK2, CARDIAK, RICK, RIP2, UNQ277/PRO314/PRO34092
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d6rn8a_
  • Chain 'B':
    Compound: receptor-interacting serine/threonine-protein kinase 2
    Species: Homo sapiens [TaxId:9606]
    Gene: RIPK2, CARDIAK, RICK, RIP2, UNQ277/PRO314/PRO34092
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d6rn8b_
  • Heterogens: K9T, CA, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >6rn8A (A:)
gmngeaicsalptipyhkladlrylsrgasgtvssarhadwrvqvavkhlhihtplldse
rkdvlreaeilhkarfsyilpilgicnepeflgivteympngslnellhrkteypdvawp
lrfrilheialgvnylhnmtppllhhdlktqnilldnefhvkiadfglskwrmmslsqsr
ssksapeggtiiymppenyepgqksrasikhdiysyavitwevlsrkqpfedvtnplqim
ysvsqghrpvineeslpydiphrarmisliesgwaqnpderpsflkclielepvlrtfee
itfleaviqlk

    Sequence, based on observed residues (ATOM records): (download) 
    >6rn8A (A:)
aicsalptipyhkladlrylsrgasgtvssarhadwrvqvavkhlhplldserkdvlrea
eilhkarfsyilpilgicnepeflgivteympngslnellhrkteypdvawplrfrilhe
ialgvnylhnmtppllhhdlktqnilldnefhvkiadfglskwrmgtiiymppenyesik
hdiysyavitwevlsrkqpfedvtnplqimysvsqghrpvineeslpydiphrarmisli
esgwaqnpderpsflkclielepvlrtfeeitfleaviqlk

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >6rn8B (B:)
gmngeaicsalptipyhkladlrylsrgasgtvssarhadwrvqvavkhlhihtplldse
rkdvlreaeilhkarfsyilpilgicnepeflgivteympngslnellhrkteypdvawp
lrfrilheialgvnylhnmtppllhhdlktqnilldnefhvkiadfglskwrmmslsqsr
ssksapeggtiiymppenyepgqksrasikhdiysyavitwevlsrkqpfedvtnplqim
ysvsqghrpvineeslpydiphrarmisliesgwaqnpderpsflkclielepvlrtfee
itfleaviqlk

    Sequence, based on observed residues (ATOM records): (download) 
    >6rn8B (B:)
aicsalptipyhkladlrylsrgagtvssarhadwrvqvavkhlhiplldserkdvlrea
eilhkarfsyilpilgicnepeflgivteympngslnellhrkteypdvawplrfrilhe
ialgvnylhnmtppllhhdlktqnilldnefhvkiadfglskwrmeggtiiymppenyep
sikhdiysyavitwevlsrkqpfedvtnplqimysvsqghrpvineeslpydiphrarmi
sliesgwaqnpderpsflkclielepvlrtfeeitfleaviqlk