PDB entry 6rir

View 6rir on RCSB PDB site
Description: Crystal structure of phosphorylated Rab8a in complex with the Rab-binding domain of RILPL2
Class: signaling protein
Keywords: membrane trafficking, Rab GTPase, effector, SIGNALING PROTEIN
Deposited on 2019-04-25, released 2020-01-29
The last revision prior to the SCOPe 2.08 freeze date was dated 2020-04-15, with a file datestamp of 2020-04-10.
Experiment type: XRAY
Resolution: 1.77 Å
R-factor: N/A
AEROSPACI score: 0.38 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Ras-related protein Rab-8A
    Species: Homo sapiens [TaxId:9606]
    Gene: Rab8a, Mel, Rab8
    Database cross-references and differences (RAF-indexed):
    • Uniprot P61006
      • engineered mutation (69)
    Domains in SCOPe 2.08: d6rira_
  • Chain 'B':
    Compound: Ras-related protein Rab-8A
    Species: Homo sapiens [TaxId:9606]
    Gene: Rab8a, Mel, Rab8
    Database cross-references and differences (RAF-indexed):
    • Uniprot P61006
      • engineered mutation (69)
    Domains in SCOPe 2.08: d6rirb1, d6rirb2
  • Chain 'C':
    Compound: RILP-like protein 2
    Species: Homo sapiens [TaxId:9606]
    Gene: RILPL2, RLP2
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q969X0 (6-End)
      • expression tag (5)
  • Chain 'D':
    Compound: RILP-like protein 2
    Species: Homo sapiens [TaxId:9606]
    Gene: RILPL2, RLP2
    Database cross-references and differences (RAF-indexed):
  • Heterogens: TPO, GTP, MG, GOL, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >6rirA (A:)
gshmaktydylfkllligdsgvgktcvlfrfsedafnstfistigidfkirtieldgkri
klqiwdtaglerfrtittayyrgamgimlvyditneksfdnirnwirnieehasadvekm
ilgnkcdvndkrqvskergeklaldygikfmetsakaninvenafftlardikakmdkkl
egns

    Sequence, based on observed residues (ATOM records): (download) 
    >6rirA (A:)
tydylfkllligdsgvgktcvlfrfsedafnstfistigidfkirtieldgkriklqiwd
taglerfrtittayyrgamgimlvyditneksfdnirnwirnieehasadvekmilgnkc
dvndkrqvskergeklaldygikfmetsakaninvenafftlardikakmdkk

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >6rirB (B:)
gshmaktydylfkllligdsgvgktcvlfrfsedafnstfistigidfkirtieldgkri
klqiwdtaglerfrtittayyrgamgimlvyditneksfdnirnwirnieehasadvekm
ilgnkcdvndkrqvskergeklaldygikfmetsakaninvenafftlardikakmdkkl
egns

    Sequence, based on observed residues (ATOM records): (download) 
    >6rirB (B:)
aktydylfkllligdsgvgktcvlfrfsedafnstfistigidfkirtieldgkriklqi
wdtaglerfrtittayyrgamgimlvyditneksfdnirnwirnieehasadvekmilgn
kcdvndkrqvskergeklaldygikfmetsakaninvenafftlardikakmdkk

  • Chain 'C':
    No sequence available.

  • Chain 'D':
    No sequence available.