PDB entry 6rch

View 6rch on RCSB PDB site
Description: Crystal structure of Casein kinase I isoform delta (CK1 delta) complexed with SR4133 inhibitor
Class: transferase
Keywords: CK1 delta, CK1d, kinase inhibitor, Structural Genomics, Structural Genomics Consortium, SGC, TRANSFERASE
Deposited on 2019-04-11, released 2020-03-25
The last revision prior to the SCOPe 2.08 freeze date was dated 2020-03-25, with a file datestamp of 2020-03-20.
Experiment type: XRAY
Resolution: 1.45 Å
R-factor: N/A
AEROSPACI score: 0.51 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Casein kinase I isoform delta
    Species: Homo sapiens [TaxId:9606]
    Gene: CSNK1D, HCKID
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d6rcha_
  • Chain 'B':
    Compound: Casein kinase I isoform delta
    Species: Homo sapiens [TaxId:9606]
    Gene: CSNK1D, HCKID
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d6rchb_
  • Heterogens: SO4, EDO, NA, K0B, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >6rchA (A:)
smmelrvgnryrlgrkigsgsfgdiylgtdiaageevaiklecvktkhpqlhieskiykm
mqggvgiptirwcgaegdynvmvmellgpsledlfnfcsrkfslktvllladqmisriey
ihsknfihrdvkpdnflmglgkkgnlvyiidfglakkyrdarthqhipyrenknltgtar
yasinthlgieqsrrddleslgyvlmyfnlgslpwqglkaatkrqkyerisekkmstpie
vlckgypsefatylnfcrslrfddkpdysylrqlfrnlfhrqgfsydyvfdwnmlk

    Sequence, based on observed residues (ATOM records): (download) 
    >6rchA (A:)
elrvgnryrlgrkigsgsfgdiylgtdiaageevaiklecvktkhpqlhieskiykmmqg
gvgiptirwcgaegdynvmvmellgpsledlfnfcsrkfslktvllladqmisrieyihs
knfihrdvkpdnflmglgkkgnlvyiidfglakkyrdarthqhipyrenknltgtaryas
inthlgieqsrrddleslgyvlmyfnlgslpwqglkaatkrqkyerisekkmstpievlc
kgypsefatylnfcrslrfddkpdysylrqlfrnlfhrqgfsydyvfdwnmlk

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >6rchB (B:)
smmelrvgnryrlgrkigsgsfgdiylgtdiaageevaiklecvktkhpqlhieskiykm
mqggvgiptirwcgaegdynvmvmellgpsledlfnfcsrkfslktvllladqmisriey
ihsknfihrdvkpdnflmglgkkgnlvyiidfglakkyrdarthqhipyrenknltgtar
yasinthlgieqsrrddleslgyvlmyfnlgslpwqglkaatkrqkyerisekkmstpie
vlckgypsefatylnfcrslrfddkpdysylrqlfrnlfhrqgfsydyvfdwnmlk

    Sequence, based on observed residues (ATOM records): (download) 
    >6rchB (B:)
melrvgnryrlgrkigsgsfgdiylgtdiaageevaiklecvktkhpqlhieskiykmmq
ggvgiptirwcgaegdynvmvmellgpsledlfnfcsrkfslktvllladqmisrieyih
sknfihrdvkpdnflmglgkkgnlvyiidfglakkyrdarthqhipyrenknltgtarya
sinthlgieqsrrddleslgyvlmyfnlgslpwqglkaatkrqkyerisekkmstpievl
ckgypsefatylnfcrslrfddkpdysylrqlfrnlfhrqgfsydyvfdwnml