PDB entry 6ram

View 6ram on RCSB PDB site
Description: heterodimeric abc exporter tmrab under turnover conditions in asymmetric unlocked return conformation with wider opened intracellular gate
Deposited on 2019-04-06, released 2019-07-31
The last revision was dated 2019-12-18, with a file datestamp of 2019-12-13.
Experiment type: EM
Resolution: 3.8 Å
R-factor: N/A
AEROSPACI score: 0.08 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Multidrug resistance ABC transporter ATP-binding and permease protein
    Species: Thermus thermophilus [TaxId:274]
    Gene: TT_C0976
    Database cross-references and differences (RAF-indexed):
  • Chain 'B':
    Compound: Multidrug resistance ABC transporter ATP-binding and permease protein
    Species: Thermus thermophilus [TaxId:274]
    Gene: TT_C0977
    Database cross-references and differences (RAF-indexed):
  • Chain 'C':
    Compound: Nanobody Nb9F10
    Species: Vicugna pacos [TaxId:30538]
    Database cross-references and differences (RAF-indexed):
    • PDB 6RAM
  • Heterogens: ADP, MG, ATP

PDB Chain Sequences:
This PDB entry is not classified in SCOPe 2.08, so the chain sequences below are not included in the ASTRAL sequence sets.

  • Chain 'A':
    Sequence, based on SEQRES records:
    >6ramA (A:)
mtedtyskafdralfarilryvwpyrlqvvlallfllvvtlaaaatplffkwaidlalvp
teprplaerfhlllwislgflavravhfaatygetyliqwvgqrvlfdlrsdlfaklmrl
hpgfydrnpvgrlmtrvtsdvdainqfitgglvgviadlftlvgllgfmlflspkltlvv
llvapvllavttwvrlgmrsayremrlrlarvnaalqenlsgvetiqlfvkerereekfd
rlnrdlfrawveiirwfalffpvvgflgdfavaslvyygggevvrgavslgllvafvdyt
rqlfqplqdlsdkfnlfqgamasaerifgvldteeelkdpedptpirgfrgevefrdvwl
aytpkgveptekdwvlkgvsfrvrpgekvalvgatgagktsvvsliarfydpqrgcvfld
gvdvrryrqeelrrhvgivlqepflfsgtvldnlrlfdpsvpperveevarflgahefil
rlpkgyqtvlgergaglstgekqllalvrallaspdillildeatasvdsetekrlqeal
ykamegrtsliiahrlstirhvdrilvfrkgrlveegsheellakggyyaalyrlqfqea
klggggenlyfqghhhhhhhhhh

    Sequence, based on observed residues (ATOM records):
    >6ramA (A:)
dralfarilryvwpyrlqvvlallfllvvtlaaaatplffkwaidlalvpteprplaerf
hlllwislgflavravhfaatygetyliqwvgqrvlfdlrsdlfaklmrlhpgfydrnpv
grlmtrvtsdvdainqfitgglvgviadlftlvgllgfmlflspkltlvvllvapvllav
ttwvrlgmrsayremrlrlarvnaalqenlsgvetiqlfvkerereekfdrlnrdlfraw
veiirwfalffpvvgflgdfavaslvyygggevvrgavslgllvafvdytrqlfqplqdl
sdkfnlfqgamasaerifgvldteeelkdpedptpirgfrgevefrdvwlaytpkgvept
ekdwvlkgvsfrvrpgekvalvgatgagktsvvsliarfydpqrgcvfldgvdvrryrqe
elrrhvgivlqepflfsgtvldnlrlfdpsvpperveevarflgahefilrlpkgyqtvl
gergaglstgekqllalvrallaspdillildeatasvdsetekrlqealykamegrtsl
iiahrlstirhvdrilvfrkgrlveegsheellakggyyaalyrlqfq

  • Chain 'B':
    Sequence, based on SEQRES records:
    >6ramB (B:)
mtgrsaapllrrlwpyvgryrwrylwavlaglvsifffvltpyflrlavdavqagrgfgv
yalaivasaalsgllsyamrrlavvasrqveydlrrdllhhlltldrdfyhkhrvgdlmn
rlntdlsavremvgpgilmgsrlsflvllaflsmyavnarlafyltlilpgiflamrfll
rlidrryreaqevfdristlaqeafsgirvvkgyalerrmvawfqdlnrlyvekslalar
vegplhallgflmgfafltvlwaggamvvrgelsvgelvqfnaylaqltwpilglgwvma
lyqrgltslrrlfelldekpairdedplplaledlsgevrfegvglkrdgrwllrgltlt
ipegmtlgitgrtgsgksllaalvprlldpsegrvyvgghearriplavlrkavgvapqe
pflfsetileniafgldevdrervewaarlagiheeilafpkgyetvlgergitlsggqr
qrvalaralakrpkililddalsavdaetearilqglktvlgkqttllishrtaalrhad
wiivldggriveegthesllqagglyaemdrlqkevea

    Sequence, based on observed residues (ATOM records):
    >6ramB (B:)
rsaapllrrlwpyvgryrwrylwavlaglvsifffvltpyflrlavdavqagrgfgvyal
aivasaalsgllsyamrrlavvasrqveydlrrdllhhlltldrdfyhkhrvgdlmnrln
tdlsavremvgpgilmgsrlsflvllaflsmyavnarlafyltlilpgiflamrfllrli
drryreaqevfdristlaqeafsgirvvkgyalerrmvawfqdlnrlyvekslalarveg
plhallgflmgfafltvlwaggamvvrgelsvgelvqfnaylaqltwpilglgwvmalyq
rgltslrrlfelldekpairdedplplaledlsgevrfegvglkrdgrwllrgltltipe
gmtlgitgrtgsgksllaalvprlldpsegrvyvgghearriplavlrkavgvapqepfl
fsetileniafgldevdrervewaarlagiheeilafpkgyetvlgergitlsggqrqrv
alaralakrpkililddalsavdaetearilqglktvlgkqttllishrtaalrhadwii
vldggriveegthesllqagglyaemdrlqke

  • Chain 'C':
    Sequence, based on SEQRES records:
    >6ramC (C:)
maqlqlvesggglvqpgdslrlscavsgsaldynaigwfrqapgkeregvaciskitgnt
ayadsvkgrftisrdnakntvhlqmnslkpedtavyycatvtavllpgrcvpgkywgqgt
pvtvsshhhhhhepea

    Sequence, based on observed residues (ATOM records):
    >6ramC (C:)
qlvesggglvqpgdslrlscavsgsaldynaigwfrqapgkeregvaciskitgntayad
svkgrftisrdnakntvhlqmnslkpedtavyycatvtavllpgrcvpgkywgqgtpvtv
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