PDB entry 6rai

View 6rai on RCSB PDB site
Description: Heterodimeric ABC exporter TmrAB in ATP-bound outward-facing occluded conformation
Class: transport protein
Keywords: ATP-binding cassette transporter, membrane protein, heterodimer, exporter, TRANSPORT PROTEIN
Deposited on 2019-04-06, released 2019-07-31
The last revision prior to the SCOPe 2.08 freeze date was dated 2019-12-18, with a file datestamp of 2019-12-13.
Experiment type: EM
Resolution: 2.9 Å
R-factor: N/A
AEROSPACI score: 0.17 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Multidrug resistance ABC transporter ATP-binding and permease protein
    Species: Thermus thermophilus [TaxId:274]
    Gene: TT_C0976
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q72J05
      • engineered mutation (522)
    Domains in SCOPe 2.08: d6raia1, d6raia2
  • Chain 'B':
    Compound: Multidrug resistance ABC transporter ATP-binding and permease protein
    Species: Thermus thermophilus [TaxId:274]
    Gene: TT_C0977
    Database cross-references and differences (RAF-indexed):
  • Chain 'C':
    Compound: Nanobody Nb9F10
    Species: Vicugna pacos [TaxId:30538]
    Database cross-references and differences (RAF-indexed):
    • PDB 6RAI
    Domains in SCOPe 2.08: d6raic_
  • Heterogens: ATP, MG, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >6raiA (A:)
mtedtyskafdralfarilryvwpyrlqvvlallfllvvtlaaaatplffkwaidlalvp
teprplaerfhlllwislgflavravhfaatygetyliqwvgqrvlfdlrsdlfaklmrl
hpgfydrnpvgrlmtrvtsdvdainqfitgglvgviadlftlvgllgfmlflspkltlvv
llvapvllavttwvrlgmrsayremrlrlarvnaalqenlsgvetiqlfvkerereekfd
rlnrdlfrawveiirwfalffpvvgflgdfavaslvyygggevvrgavslgllvafvdyt
rqlfqplqdlsdkfnlfqgamasaerifgvldteeelkdpedptpirgfrgevefrdvwl
aytpkgveptekdwvlkgvsfrvrpgekvalvgatgagktsvvsliarfydpqrgcvfld
gvdvrryrqeelrrhvgivlqepflfsgtvldnlrlfdpsvpperveevarflgahefil
rlpkgyqtvlgergaglstgekqllalvrallaspdillildqatasvdsetekrlqeal
ykamegrtsliiahrlstirhvdrilvfrkgrlveegsheellakggyyaalyrlqfqea
klggggenlyfqghhhhhhhhhh

    Sequence, based on observed residues (ATOM records): (download) 
    >6raiA (A:)
dralfarilryvwpyrlqvvlallfllvvtlaaaatplffkwaidlalvpteprplaerf
hlllwislgflavravhfaatygetyliqwvgqrvlfdlrsdlfaklmrlhpgfydrnpv
grlmtrvtsdvdainqfitgglvgviadlftlvgllgfmlflspkltlvvllvapvllav
ttwvrlgmrsayremrlrlarvnaalqenlsgvetiqlfvkerereekfdrlnrdlfraw
veiirwfalffpvvgflgdfavaslvyygggevvrgavslgllvafvdytrqlfqplqdl
sdkfnlfqgamasaerifgvldteeelkdpedptpirgfrgevefrdvwlaytpkgvept
ekdwvlkgvsfrvrpgekvalvgatgagktsvvsliarfydpqrgcvfldgvdvrryrqe
elrrhvgivlqepflfsgtvldnlrlfdpsvpperveevarflgahefilrlpkgyqtvl
gergaglstgekqllalvrallaspdillildqatasvdsetekrlqealykamegrtsl
iiahrlstirhvdrilvfrkgrlveegsheellakggyyaalyrlqf

  • Chain 'B':
    No sequence available.

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >6raiC (C:)
maqlqlvesggglvqpgdslrlscavsgsaldynaigwfrqapgkeregvaciskitgnt
ayadsvkgrftisrdnakntvhlqmnslkpedtavyycatvtavllpgrcvpgkywgqgt
pvtvsshhhhhhepea

    Sequence, based on observed residues (ATOM records): (download) 
    >6raiC (C:)
qlvesggglvqpgdslrlscavsgsaldynaigwfrqapgkeregvaciskitgntayad
svkgrftisrdnakntvhlqmnslkpedtavyycatvtavllpgrcvpgkywgqgtpvtv
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