PDB entry 6r6e

View 6r6e on RCSB PDB site
Description: Crystal structure of di-phosphorylated human CLK1 in complex with 5-(6,7-dichloro-1-methyl-1H-indol-3-yl)pyrimidin-4-amine
Class: signaling protein
Keywords: splicing, kinase, viral infection, SIGNALING PROTEIN
Deposited on 2019-03-27, released 2020-05-06
The last revision prior to the SCOPe 2.08 freeze date was dated 2020-05-06, with a file datestamp of 2020-05-01.
Experiment type: XRAY
Resolution: 2.25 Å
R-factor: N/A
AEROSPACI score: 0.25 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Dual specificity protein kinase CLK1
    Species: Homo sapiens [TaxId:9606]
    Gene: CLK1, CLK
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d6r6ea_
  • Heterogens: JTQ, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download)
    >6r6eA (A:)
    hlicqsgdvlsaryeivdtlgegafgkvvecidhkaggrhvavkivknvdryceaarsei
    qvlehlnttdpnstfrcvqmlewfehhghicivfellglstydfikengflpfrldhirk
    mayqicksvnflhsnklthtdlkpenilfvqsdyteaynpkikrdertlinpdikvvdfg
    satyddehhstlvstrhyrapevilalgwsqpcdvwsigcilieyylgftvfpthdskeh
    lammerilgplpkhmiqktrkrkyfhhdrldwdehssagryvsrrckplkefmlsqdveh
    erlfdliqkmleydpakritlrealkhpffdllkksi
    

    Sequence, based on observed residues (ATOM records): (download)
    >6r6eA (A:)
    sgdvlsaryeivdtlgegafgkvvecidhkaggrhvavkivknvdryceaarseiqvleh
    lnttdpnstfrcvqmlewfehhghicivfellglstydfikengflpfrldhirkmayqi
    cksvnflhsnklthtdlkpenilfvqsdyteaynpkrdertlinpdikvvdfgsatydde
    hhstlvstrhyrapevilalgwsqpcdvwsigcilieyylgftvfpthdskehlammeri
    lgplpkhmiqktrkrkyfhhdrldwdehssagryvsrrckplkefmlsqdveherlfdli
    qkmleydpakritlrealkhpffdllk