PDB entry 6r6e
View 6r6e on RCSB PDB site
Description: Crystal structure of di-phosphorylated human CLK1 in complex with 5-(6,7-dichloro-1-methyl-1H-indol-3-yl)pyrimidin-4-amine
Class: signaling protein
Keywords: splicing, kinase, viral infection, SIGNALING PROTEIN
Deposited on
2019-03-27, released
2020-05-06
The last revision prior to the SCOPe 2.08 freeze date was dated
2020-05-06, with a file datestamp of
2020-05-01.
Experiment type: XRAY
Resolution: 2.25 Å
R-factor: N/A
AEROSPACI score: 0.25
(click here for full SPACI score report)
Chains and heterogens:
- Chain 'A':
Compound: Dual specificity protein kinase CLK1
Species: Homo sapiens [TaxId:9606]
Gene: CLK1, CLK
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.08: d6r6ea_ - Heterogens: JTQ, HOH
PDB Chain Sequences:
- Chain 'A':
Sequence, based on SEQRES records: (download)
>6r6eA (A:)
hlicqsgdvlsaryeivdtlgegafgkvvecidhkaggrhvavkivknvdryceaarsei
qvlehlnttdpnstfrcvqmlewfehhghicivfellglstydfikengflpfrldhirk
mayqicksvnflhsnklthtdlkpenilfvqsdyteaynpkikrdertlinpdikvvdfg
satyddehhstlvstrhyrapevilalgwsqpcdvwsigcilieyylgftvfpthdskeh
lammerilgplpkhmiqktrkrkyfhhdrldwdehssagryvsrrckplkefmlsqdveh
erlfdliqkmleydpakritlrealkhpffdllkksi
Sequence, based on observed residues (ATOM records): (download)
>6r6eA (A:)
sgdvlsaryeivdtlgegafgkvvecidhkaggrhvavkivknvdryceaarseiqvleh
lnttdpnstfrcvqmlewfehhghicivfellglstydfikengflpfrldhirkmayqi
cksvnflhsnklthtdlkpenilfvqsdyteaynpkrdertlinpdikvvdfgsatydde
hhstlvstrhyrapevilalgwsqpcdvwsigcilieyylgftvfpthdskehlammeri
lgplpkhmiqktrkrkyfhhdrldwdehssagryvsrrckplkefmlsqdveherlfdli
qkmleydpakritlrealkhpffdllk