PDB entry 6r57

View 6r57 on RCSB PDB site
Description: crystal structure of ppep-1(e143a/y178f/e184a) in complex with substrate peptide ac-evnppvp-conh2
Deposited on 2019-03-24, released 2019-06-12
The last revision was dated 2019-08-07, with a file datestamp of 2019-08-02.
Experiment type: XRAY
Resolution: 1.9 Å
R-factor: N/A
AEROSPACI score: 0.35 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: PRO-PRO endopeptidase
    Species: Peptoclostridium difficile [TaxId:1496]
    Gene: zmp1, ppep-1, CD630_28300
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q183R7 (Start-197)
      • engineered mutation (120)
      • engineered mutation (155)
      • engineered mutation (161)
  • Chain 'B':
    Compound: PRO-PRO endopeptidase
    Species: Peptoclostridium difficile [TaxId:1496]
    Gene: zmp1, ppep-1, CD630_28300
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q183R7 (Start-197)
      • engineered mutation (120)
      • engineered mutation (155)
      • engineered mutation (161)
  • Chain 'C':
    Compound: ace-glu-val-asn-pro-pro-val-lpd
    Species: Clostridioides difficile, synthetic [TaxId:1496]
    Database cross-references and differences (RAF-indexed):
    • PDB 6R57 (Start-6)
  • Chain 'D':
    Compound: ace-glu-val-asn-pro-pro-val-lpd
    Species: Clostridioides difficile, synthetic [TaxId:1496]
    Database cross-references and differences (RAF-indexed):
    • PDB 6R57 (Start-6)
  • Heterogens: ZN, HOH

PDB Chain Sequences:
This PDB entry is not classified in SCOPe 2.08, so the chain sequences below are not included in the ASTRAL sequence sets.

  • Chain 'A':
    Sequence, based on SEQRES records:
    >6r57A (A:)
gshmdsttiqqnkdtlsqivvfptgnydkneanamvnrlanidgkylnalkqnnlkikll
sgkltdekeyaylkgvvpkgwegtgktwddvpglggstvalrigfsnkgkghdainlelh
atahaidhivlndisksaqfkqifakegrslgnvnflgvypaeffaesfayyylnqdtns
klksacpqtysflqnlak

    Sequence, based on observed residues (ATOM records):
    >6r57A (A:)
ttiqqnkdtlsqivvfptgnydkneanamvnrlanidgkylnalkqnnlkikllsgkltd
ekeyaylkgvvpkgwegtgktwddvpglggstvalrigfsnkgkghdainlelhatahai
dhivlndisksaqfkqifakegrslgnvnflgvypaeffaesfayyylnqdtnsklksac
pqtysflqnlak

  • Chain 'B':
    Sequence, based on SEQRES records:
    >6r57B (B:)
gshmdsttiqqnkdtlsqivvfptgnydkneanamvnrlanidgkylnalkqnnlkikll
sgkltdekeyaylkgvvpkgwegtgktwddvpglggstvalrigfsnkgkghdainlelh
atahaidhivlndisksaqfkqifakegrslgnvnflgvypaeffaesfayyylnqdtns
klksacpqtysflqnlak

    Sequence, based on observed residues (ATOM records):
    >6r57B (B:)
ttiqqnkdtlsqivvfptgnydkneanamvnrlanidgkylnalkqnnlkikllsgkltd
ekeyaylkgvvpkgwegtgktwddvpglggstvalrigfsnkgkghdainlelhatahai
dhivlndisksaqfkqifakegrslgnvnflgvypaeffaesfayyylnqdtnsklksac
pqtysflqnlak

  • Chain 'C':
    Sequence; same for both SEQRES and ATOM records:
    >6r57C (C:)
evnppvp

  • Chain 'D':
    Sequence; same for both SEQRES and ATOM records:
    >6r57D (D:)
evnppvp