PDB entry 6r49

View 6r49 on RCSB PDB site
Description: Aurora-A in complex with shape-diverse fragment 39
Class: transferase
Keywords: Ser/Thr kinase Allosteric site, TRANSFERASE
Deposited on 2019-03-22, released 2019-05-08
The last revision prior to the SCOPe 2.08 freeze date was dated 2019-07-10, with a file datestamp of 2019-07-05.
Experiment type: XRAY
Resolution: 2.21 Å
R-factor: N/A
AEROSPACI score: 0.27 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Aurora kinase A
    Species: Homo sapiens [TaxId:9606]
    Gene: AURKA, AIK, AIRK1, ARK1, AURA, AYK1, BTAK, IAK1, STK15, STK6
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d6r49a_
  • Heterogens: JSB, ADP, MG, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >6r49A (A:)
gameskkrqwaledfeigrplgkgkfgnvylarekqskfilalkvlfkaqlekagvehql
rreveiqshlrhpnilrlygyfhdatrvylileyaplgtvyrelqklskfdeqrtatyit
elanalsychskrvihrdikpenlllgsagelkiadfgwsvhapssrrttlagtldylpp
emiegrmhdekvdlwslgvlcyeflvgkppfeantyqetykrisrveftfpdfvtegard
lisrllkhnpsqrpmlrevlehpwitansskpsnaqnkesaskqs

    Sequence, based on observed residues (ATOM records): (download) 
    >6r49A (A:)
qwaledfeigrplgkgkfgnvylarekqskfilalkvlfkaqlekagvehqlrreveiqs
hlrhpnilrlygyfhdatrvylileyaplgtvyrelqklskfdeqrtatyitelanalsy
chskrvihrdikpenlllgsagelkiadfgwsvhapssrgtldylppemiegrmhdekvd
lwslgvlcyeflvgkppfeantyqetykrisrveftfpdfvtegardlisrllkhnpsqr
pmlrevlehpwitansskps