PDB entry 6qz7

View 6qz7 on RCSB PDB site
Description: structure of mbp-mcl-1 in complex with compound 8b
Deposited on 2019-03-11, released 2019-08-07
The last revision was dated 2020-07-29, with a file datestamp of 2020-06-29.
Experiment type: XRAY
Resolution: 2.2 Å
R-factor: N/A
AEROSPACI score: 0.35 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Maltose/maltodextrin-binding periplasmic protein,Induced myeloid leukemia cell differentiation protein Mcl-1
    Species: Homo sapiens [TaxId:9606]
    Gene: MCL1, BCL2L3
    Database cross-references and differences (RAF-indexed):
    • Uniprot P0AEY0 (1-366)
      • engineered mutation (239)
      • linker (367-368)
    • Uniprot Q07820 (369-517)
      • engineered mutation (390)
      • engineered mutation (393)
      • engineered mutation (397)
  • Heterogens: JLE, NA, HOH

PDB Chain Sequences:
This PDB entry is not classified in SCOPe 2.08, so the chain sequences below are not included in the ASTRAL sequence sets.

  • Chain 'A':
    Sequence, based on SEQRES records:
    >6qz7A (A:)
mkieegklviwingdkgynglaevgkkfekdtgikvtvehpdkleekfpqvaatgdgpdi
ifwahdrfggyaqsgllaeitpdkafqdklypftwdavryngkliaypiavealsliynk
dllpnppktweeipaldkelkakgksalmfnlqepyftwpliaadggyafkyaagkydik
dvgvdnagakagltflvdliknkhmnadtdysiaeaafnkgetamtingpwawsnidtsa
vnygvtvlptfkgqpskpfvgvlsaginaaspnkelakeflenylltdegleavnkdkpl
gavalksyeeelakdpriaatmenaqkgeimpnipqmsafwyavrtavinaasgrqtvde
alkdaqtgselyrqsleiisrylreqatgaadtapmgasgatsrkaletlrrvgdgvqrn
hetafqgmlrkldikneddvkslsrvmihvfsdgvtnwgrivtlisfgafvakhlktinq
escieplaesitdvlvrtkrdwlvkqrgwdgfveffhv

    Sequence, based on observed residues (ATOM records):
    >6qz7A (A:)
kieegklviwingdkgynglaevgkkfekdtgikvtvehpdkleekfpqvaatgdgpdii
fwahdrfggyaqsgllaeitpdkafqdklypftwdavryngkliaypiavealsliynkd
llpnppktweeipaldkelkakgksalmfnlqepyftwpliaadggyafkyydikdvgvd
nagakagltflvdliknkhmnadtdysiaeaafnkgetamtingpwawsnidtsavnygv
tvlptfkgqpskpfvgvlsaginaaspnkelakeflenylltdegleavnkdkplgaval
ksyeeelakdpriaatmenaqkgeimpnipqmsafwyavrtavinaasgrqtvdealkda
qtgselyrqsleiisrylreqatgaadtapmgasgatsrkaletlrrvgdgvqrnhetaf
qgmlrkldikneddvkslsrvmihvfsdgvtnwgrivtlisfgafvakhlktinqescie
plaesitdvlvrtkrdwlvkqrgwdgfveffhv