PDB entry 6qz5

View 6qz5 on RCSB PDB site
Description: Structure of Mcl-1 in complex with compound 8a
Class: apoptosis
Keywords: Apoptosis-inhibitor complex, Mcl1, Small molecule inhibitor, APOPTOSIS
Deposited on 2019-03-11, released 2019-08-07
The last revision prior to the SCOPe 2.08 freeze date was dated 2019-09-18, with a file datestamp of 2019-09-13.
Experiment type: XRAY
Resolution: 2 Å
R-factor: N/A
AEROSPACI score: 0.31 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Induced myeloid leukemia cell differentiation protein Mcl-1
    Species: Homo sapiens [TaxId:9606]
    Gene: MCL1, BCL2L3
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q07820 (13-End)
      • expression tag (12)
    Domains in SCOPe 2.08: d6qz5a1, d6qz5a2
  • Heterogens: JLE, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >6qz5A (A:)
mhhhhhhlvprgsedelyrqsleiisrylreqatgakdtkpmgrsgatsrkaletlrrvg
dgvqrnhetafqgmlrkldikneddvkslsrvmihvfsdgvtnwgrivtlisfgafvakh
lktinqescieplaesitdvlvrtkrdwlvkqrgwdgfveffhvedlegg

    Sequence, based on observed residues (ATOM records): (download) 
    >6qz5A (A:)
sedelyrqsleiisrylreqatgakdtkpmgrsgatsrkaletlrrvgdgvqrnhetafq
gmlrkldikneddvkslsrvmihvfsdgvtnwgrivtlisfgafvakhlktinqesciep
laesitdvlvrtkrdwlvkqrgwdgfveffh