PDB entry 6qxu

View 6qxu on RCSB PDB site
Description: human tnks1 in complex with 6,8-difluoro-2-[4-(1-hydroxy-1-methyl- ethyl)-phenyl]-3h-quinazolin-4-one
Deposited on 2019-03-08, released 2019-08-14
The last revision was dated 2019-09-25, with a file datestamp of 2019-09-20.
Experiment type: XRAY
Resolution: 1.2 Å
R-factor: N/A
AEROSPACI score: 0.65 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Poly [ADP-ribose] polymerase tankyrase-1
    Species: Homo sapiens [TaxId:9606]
    Gene: TNKS, PARP5A, PARPL, TIN1, TINF1, TNKS1
    Database cross-references and differences (RAF-indexed):
  • Heterogens: BME, JKN, ZN, HOH

PDB Chain Sequences:
This PDB entry is not classified in SCOPe 2.08, so the chain sequences below are not included in the ASTRAL sequence sets.

  • Chain 'A':
    Sequence, based on SEQRES records:
    >6qxuA (A:)
qgtilldlapedkeyqsveeemqstirehrdggnaggifnrynviriqkvvnkklrerfc
hrqkevseenhnhhnermlfhgspfinaiihkgfderhayiggmfgagiyfaenssksnq
yvygigggtgcpthkdrscyichrqmlfcrvtlgksflqfstmkmahappghhsvigrps
vnglayaeyviyrgeqaypeylityqimkpe

    Sequence, based on observed residues (ATOM records):
    >6qxuA (A:)
gtilldlapedkeyqsveeemqstirehrdggnaggifnrynviriqkvvnkklrerfch
rqkevseenhnhhnermlfhgspfinaiihkgfderhayiggmfgagiyfaenssksnqy
vygigggtgcpthkdrscyichrqmlfcrvtlgksflqfstmkmahappghhsvigrpsv
nglayaeyviyrgeqaypeylityqimkp