PDB entry 6qxl

View 6qxl on RCSB PDB site
Description: crystal structure of pyruvate kinase ii (pyka) from pseudomonas aeruginosa in complex with sodium malonate, magnesium and glucose-6- phosphate
Deposited on 2019-03-07, released 2019-09-11
The last revision was dated 2020-07-29, with a file datestamp of 2020-06-29.
Experiment type: XRAY
Resolution: 2.43 Å
R-factor: N/A
AEROSPACI score: 0.31 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: pyruvate kinase
    Species: Pseudomonas aeruginosa [TaxId:287]
    Gene: pykA, pyk, pykA_1, C8257_26620, CAZ10_21690, DZ940_08845, NCTC13719_04679, PAERUG_E15_London_28_01_14_03018, PAMH19_3832, RW109_RW109_05666
    Database cross-references and differences (RAF-indexed):
  • Chain 'B':
    Compound: pyruvate kinase
    Species: Pseudomonas aeruginosa [TaxId:287]
    Gene: pykA, pyk, pykA_1, C8257_26620, CAZ10_21690, DZ940_08845, NCTC13719_04679, PAERUG_E15_London_28_01_14_03018, PAMH19_3832, RW109_RW109_05666
    Database cross-references and differences (RAF-indexed):
  • Chain 'C':
    Compound: pyruvate kinase
    Species: Pseudomonas aeruginosa [TaxId:287]
    Gene: pykA, pyk, pykA_1, C8257_26620, CAZ10_21690, DZ940_08845, NCTC13719_04679, PAERUG_E15_London_28_01_14_03018, PAMH19_3832, RW109_RW109_05666
    Database cross-references and differences (RAF-indexed):
  • Chain 'D':
    Compound: pyruvate kinase
    Species: Pseudomonas aeruginosa [TaxId:287]
    Gene: pykA, pyk, pykA_1, C8257_26620, CAZ10_21690, DZ940_08845, NCTC13719_04679, PAERUG_E15_London_28_01_14_03018, PAMH19_3832, RW109_RW109_05666
    Database cross-references and differences (RAF-indexed):
  • Chain 'E':
    Compound: pyruvate kinase
    Species: Pseudomonas aeruginosa [TaxId:287]
    Gene: pykA, pyk, pykA_1, C8257_26620, CAZ10_21690, DZ940_08845, NCTC13719_04679, PAERUG_E15_London_28_01_14_03018, PAMH19_3832, RW109_RW109_05666
    Database cross-references and differences (RAF-indexed):
  • Chain 'F':
    Compound: pyruvate kinase
    Species: Pseudomonas aeruginosa [TaxId:287]
    Gene: pykA, pyk, pykA_1, C8257_26620, CAZ10_21690, DZ940_08845, NCTC13719_04679, PAERUG_E15_London_28_01_14_03018, PAMH19_3832, RW109_RW109_05666
    Database cross-references and differences (RAF-indexed):
  • Chain 'G':
    Compound: pyruvate kinase
    Species: Pseudomonas aeruginosa [TaxId:287]
    Gene: pykA, pyk, pykA_1, C8257_26620, CAZ10_21690, DZ940_08845, NCTC13719_04679, PAERUG_E15_London_28_01_14_03018, PAMH19_3832, RW109_RW109_05666
    Database cross-references and differences (RAF-indexed):
  • Chain 'H':
    Compound: pyruvate kinase
    Species: Pseudomonas aeruginosa [TaxId:287]
    Gene: pykA, pyk, pykA_1, C8257_26620, CAZ10_21690, DZ940_08845, NCTC13719_04679, PAERUG_E15_London_28_01_14_03018, PAMH19_3832, RW109_RW109_05666
    Database cross-references and differences (RAF-indexed):
  • Chain 'I':
    Compound: pyruvate kinase
    Species: Pseudomonas aeruginosa [TaxId:287]
    Gene: pykA, pyk, pykA_1, C8257_26620, CAZ10_21690, DZ940_08845, NCTC13719_04679, PAERUG_E15_London_28_01_14_03018, PAMH19_3832, RW109_RW109_05666
    Database cross-references and differences (RAF-indexed):
  • Chain 'J':
    Compound: pyruvate kinase
    Species: Pseudomonas aeruginosa [TaxId:287]
    Gene: pykA, pyk, pykA_1, C8257_26620, CAZ10_21690, DZ940_08845, NCTC13719_04679, PAERUG_E15_London_28_01_14_03018, PAMH19_3832, RW109_RW109_05666
    Database cross-references and differences (RAF-indexed):
  • Chain 'K':
    Compound: pyruvate kinase
    Species: Pseudomonas aeruginosa [TaxId:287]
    Gene: pykA, pyk, pykA_1, C8257_26620, CAZ10_21690, DZ940_08845, NCTC13719_04679, PAERUG_E15_London_28_01_14_03018, PAMH19_3832, RW109_RW109_05666
    Database cross-references and differences (RAF-indexed):
  • Chain 'L':
    Compound: pyruvate kinase
    Species: Pseudomonas aeruginosa [TaxId:287]
    Gene: pykA, pyk, pykA_1, C8257_26620, CAZ10_21690, DZ940_08845, NCTC13719_04679, PAERUG_E15_London_28_01_14_03018, PAMH19_3832, RW109_RW109_05666
    Database cross-references and differences (RAF-indexed):
  • Heterogens: G6P, MLI, MG, GOL, HOH

PDB Chain Sequences:
This PDB entry is not classified in SCOPe 2.08, so the chain sequences below are not included in the ASTRAL sequence sets.

  • Chain 'A':
    Sequence; same for both SEQRES and ATOM records:
    >6qxlA (A:)
msvrrtkivatlgpasnspevleqlilagidvarlnfshgtpdehrararlvrelaakhg
rfvallgdlqgpkiriakfankrielqvgdkfrfstshardagtqevvgidypdlvkdcg
vgdelllddgrvvmvveevaadelrcrvliggplsdhkginrrgggltapaltdkdkadi
klaadmdldyvavsfprdakdmeyarrllteaggkawlvakieraeavadddaldglira
sdavmvargdlgveigdaelvgiqkkiilharrnnkvvitatqmmesmihspmptraevs
dvanavldytdavmlsaesaageypveavkamarvcqgaekhptsqksshrlgqtfdrcd
esialasmytanhfpgikaiicltesgftplimsrirssvpiyaysphretqarvamfrg
vetipfdpaalpaekvsqaavdellkrgvvtkgdwviltkgdsytaqggtntmkvlhvgd
llv

  • Chain 'B':
    Sequence; same for both SEQRES and ATOM records:
    >6qxlB (B:)
msvrrtkivatlgpasnspevleqlilagidvarlnfshgtpdehrararlvrelaakhg
rfvallgdlqgpkiriakfankrielqvgdkfrfstshardagtqevvgidypdlvkdcg
vgdelllddgrvvmvveevaadelrcrvliggplsdhkginrrgggltapaltdkdkadi
klaadmdldyvavsfprdakdmeyarrllteaggkawlvakieraeavadddaldglira
sdavmvargdlgveigdaelvgiqkkiilharrnnkvvitatqmmesmihspmptraevs
dvanavldytdavmlsaesaageypveavkamarvcqgaekhptsqksshrlgqtfdrcd
esialasmytanhfpgikaiicltesgftplimsrirssvpiyaysphretqarvamfrg
vetipfdpaalpaekvsqaavdellkrgvvtkgdwviltkgdsytaqggtntmkvlhvgd
llv

  • Chain 'C':
    Sequence; same for both SEQRES and ATOM records:
    >6qxlC (C:)
msvrrtkivatlgpasnspevleqlilagidvarlnfshgtpdehrararlvrelaakhg
rfvallgdlqgpkiriakfankrielqvgdkfrfstshardagtqevvgidypdlvkdcg
vgdelllddgrvvmvveevaadelrcrvliggplsdhkginrrgggltapaltdkdkadi
klaadmdldyvavsfprdakdmeyarrllteaggkawlvakieraeavadddaldglira
sdavmvargdlgveigdaelvgiqkkiilharrnnkvvitatqmmesmihspmptraevs
dvanavldytdavmlsaesaageypveavkamarvcqgaekhptsqksshrlgqtfdrcd
esialasmytanhfpgikaiicltesgftplimsrirssvpiyaysphretqarvamfrg
vetipfdpaalpaekvsqaavdellkrgvvtkgdwviltkgdsytaqggtntmkvlhvgd
llv

  • Chain 'D':
    Sequence; same for both SEQRES and ATOM records:
    >6qxlD (D:)
msvrrtkivatlgpasnspevleqlilagidvarlnfshgtpdehrararlvrelaakhg
rfvallgdlqgpkiriakfankrielqvgdkfrfstshardagtqevvgidypdlvkdcg
vgdelllddgrvvmvveevaadelrcrvliggplsdhkginrrgggltapaltdkdkadi
klaadmdldyvavsfprdakdmeyarrllteaggkawlvakieraeavadddaldglira
sdavmvargdlgveigdaelvgiqkkiilharrnnkvvitatqmmesmihspmptraevs
dvanavldytdavmlsaesaageypveavkamarvcqgaekhptsqksshrlgqtfdrcd
esialasmytanhfpgikaiicltesgftplimsrirssvpiyaysphretqarvamfrg
vetipfdpaalpaekvsqaavdellkrgvvtkgdwviltkgdsytaqggtntmkvlhvgd
llv

  • Chain 'E':
    Sequence; same for both SEQRES and ATOM records:
    >6qxlE (E:)
msvrrtkivatlgpasnspevleqlilagidvarlnfshgtpdehrararlvrelaakhg
rfvallgdlqgpkiriakfankrielqvgdkfrfstshardagtqevvgidypdlvkdcg
vgdelllddgrvvmvveevaadelrcrvliggplsdhkginrrgggltapaltdkdkadi
klaadmdldyvavsfprdakdmeyarrllteaggkawlvakieraeavadddaldglira
sdavmvargdlgveigdaelvgiqkkiilharrnnkvvitatqmmesmihspmptraevs
dvanavldytdavmlsaesaageypveavkamarvcqgaekhptsqksshrlgqtfdrcd
esialasmytanhfpgikaiicltesgftplimsrirssvpiyaysphretqarvamfrg
vetipfdpaalpaekvsqaavdellkrgvvtkgdwviltkgdsytaqggtntmkvlhvgd
llv

  • Chain 'F':
    Sequence; same for both SEQRES and ATOM records:
    >6qxlF (F:)
msvrrtkivatlgpasnspevleqlilagidvarlnfshgtpdehrararlvrelaakhg
rfvallgdlqgpkiriakfankrielqvgdkfrfstshardagtqevvgidypdlvkdcg
vgdelllddgrvvmvveevaadelrcrvliggplsdhkginrrgggltapaltdkdkadi
klaadmdldyvavsfprdakdmeyarrllteaggkawlvakieraeavadddaldglira
sdavmvargdlgveigdaelvgiqkkiilharrnnkvvitatqmmesmihspmptraevs
dvanavldytdavmlsaesaageypveavkamarvcqgaekhptsqksshrlgqtfdrcd
esialasmytanhfpgikaiicltesgftplimsrirssvpiyaysphretqarvamfrg
vetipfdpaalpaekvsqaavdellkrgvvtkgdwviltkgdsytaqggtntmkvlhvgd
llv

  • Chain 'G':
    Sequence; same for both SEQRES and ATOM records:
    >6qxlG (G:)
msvrrtkivatlgpasnspevleqlilagidvarlnfshgtpdehrararlvrelaakhg
rfvallgdlqgpkiriakfankrielqvgdkfrfstshardagtqevvgidypdlvkdcg
vgdelllddgrvvmvveevaadelrcrvliggplsdhkginrrgggltapaltdkdkadi
klaadmdldyvavsfprdakdmeyarrllteaggkawlvakieraeavadddaldglira
sdavmvargdlgveigdaelvgiqkkiilharrnnkvvitatqmmesmihspmptraevs
dvanavldytdavmlsaesaageypveavkamarvcqgaekhptsqksshrlgqtfdrcd
esialasmytanhfpgikaiicltesgftplimsrirssvpiyaysphretqarvamfrg
vetipfdpaalpaekvsqaavdellkrgvvtkgdwviltkgdsytaqggtntmkvlhvgd
llv

  • Chain 'H':
    Sequence; same for both SEQRES and ATOM records:
    >6qxlH (H:)
msvrrtkivatlgpasnspevleqlilagidvarlnfshgtpdehrararlvrelaakhg
rfvallgdlqgpkiriakfankrielqvgdkfrfstshardagtqevvgidypdlvkdcg
vgdelllddgrvvmvveevaadelrcrvliggplsdhkginrrgggltapaltdkdkadi
klaadmdldyvavsfprdakdmeyarrllteaggkawlvakieraeavadddaldglira
sdavmvargdlgveigdaelvgiqkkiilharrnnkvvitatqmmesmihspmptraevs
dvanavldytdavmlsaesaageypveavkamarvcqgaekhptsqksshrlgqtfdrcd
esialasmytanhfpgikaiicltesgftplimsrirssvpiyaysphretqarvamfrg
vetipfdpaalpaekvsqaavdellkrgvvtkgdwviltkgdsytaqggtntmkvlhvgd
llv

  • Chain 'I':
    Sequence; same for both SEQRES and ATOM records:
    >6qxlI (I:)
msvrrtkivatlgpasnspevleqlilagidvarlnfshgtpdehrararlvrelaakhg
rfvallgdlqgpkiriakfankrielqvgdkfrfstshardagtqevvgidypdlvkdcg
vgdelllddgrvvmvveevaadelrcrvliggplsdhkginrrgggltapaltdkdkadi
klaadmdldyvavsfprdakdmeyarrllteaggkawlvakieraeavadddaldglira
sdavmvargdlgveigdaelvgiqkkiilharrnnkvvitatqmmesmihspmptraevs
dvanavldytdavmlsaesaageypveavkamarvcqgaekhptsqksshrlgqtfdrcd
esialasmytanhfpgikaiicltesgftplimsrirssvpiyaysphretqarvamfrg
vetipfdpaalpaekvsqaavdellkrgvvtkgdwviltkgdsytaqggtntmkvlhvgd
llv

  • Chain 'J':
    Sequence, based on SEQRES records:
    >6qxlJ (J:)
msvrrtkivatlgpasnspevleqlilagidvarlnfshgtpdehrararlvrelaakhg
rfvallgdlqgpkiriakfankrielqvgdkfrfstshardagtqevvgidypdlvkdcg
vgdelllddgrvvmvveevaadelrcrvliggplsdhkginrrgggltapaltdkdkadi
klaadmdldyvavsfprdakdmeyarrllteaggkawlvakieraeavadddaldglira
sdavmvargdlgveigdaelvgiqkkiilharrnnkvvitatqmmesmihspmptraevs
dvanavldytdavmlsaesaageypveavkamarvcqgaekhptsqksshrlgqtfdrcd
esialasmytanhfpgikaiicltesgftplimsrirssvpiyaysphretqarvamfrg
vetipfdpaalpaekvsqaavdellkrgvvtkgdwviltkgdsytaqggtntmkvlhvgd
llv

    Sequence, based on observed residues (ATOM records):
    >6qxlJ (J:)
msvrrtkivatlgpasnspevleqlilagidvarlnfshgtpdehrararlvrelaakhg
rfvallgdlqgpkiriahkginrrgggltapaltdkdkadiklaadmdldyvavsfprda
kdmeyarrllteaggkawlvakieraeavadddaldglirasdavmvargdlgveigdae
lvgiqkkiilharrnnkvvitatqmmesmihspmptraevsdvanavldytdavmlsaes
aageypveavkamarvcqgaekhptsqksshrlgqtfdrcdesialasmytanhfpgika
iicltesgftplimsrirssvpiyaysphretqarvamfrgvetipfdpaalpaekvsqa
avdellkrgvvtkgdwviltkgdsytaqggtntmkvlhvgdllv

  • Chain 'K':
    Sequence, based on SEQRES records:
    >6qxlK (K:)
msvrrtkivatlgpasnspevleqlilagidvarlnfshgtpdehrararlvrelaakhg
rfvallgdlqgpkiriakfankrielqvgdkfrfstshardagtqevvgidypdlvkdcg
vgdelllddgrvvmvveevaadelrcrvliggplsdhkginrrgggltapaltdkdkadi
klaadmdldyvavsfprdakdmeyarrllteaggkawlvakieraeavadddaldglira
sdavmvargdlgveigdaelvgiqkkiilharrnnkvvitatqmmesmihspmptraevs
dvanavldytdavmlsaesaageypveavkamarvcqgaekhptsqksshrlgqtfdrcd
esialasmytanhfpgikaiicltesgftplimsrirssvpiyaysphretqarvamfrg
vetipfdpaalpaekvsqaavdellkrgvvtkgdwviltkgdsytaqggtntmkvlhvgd
llv

    Sequence, based on observed residues (ATOM records):
    >6qxlK (K:)
msvrrtkivatlgpasnspevleqlilagidvarlnfshgtpdehrararlvrelaakhg
rfvallgdlqgpkiriakfankrielqvgdkfrfstshardagtqevvgidypdlvkdcg
vgdelllddgrvvmvveevaadelrcrvliggplsdhkginrrgggltapaltdkdkadi
klaadmdldyvavsfprdakmeyarrllteaggkawlvakieraeavadddaldgliras
davmvargdlgveigdaelvgiqkkiilharrnnkvvitatqmmesmihspmptraevsd
vanavldytdavmlsaesaageypveavkamarvcqgaekhptsqksshrlgqtfdrcde
sialasmytanhfpgikaiicltesgftplimsrirssvpiyaysphretqarvamfrgv
etipfdpaalpaekvsqaavdellkrgvvtkgdwviltkgdsytaqggtntmkvlhvgdl
lv

  • Chain 'L':
    Sequence; same for both SEQRES and ATOM records:
    >6qxlL (L:)
msvrrtkivatlgpasnspevleqlilagidvarlnfshgtpdehrararlvrelaakhg
rfvallgdlqgpkiriakfankrielqvgdkfrfstshardagtqevvgidypdlvkdcg
vgdelllddgrvvmvveevaadelrcrvliggplsdhkginrrgggltapaltdkdkadi
klaadmdldyvavsfprdakdmeyarrllteaggkawlvakieraeavadddaldglira
sdavmvargdlgveigdaelvgiqkkiilharrnnkvvitatqmmesmihspmptraevs
dvanavldytdavmlsaesaageypveavkamarvcqgaekhptsqksshrlgqtfdrcd
esialasmytanhfpgikaiicltesgftplimsrirssvpiyaysphretqarvamfrg
vetipfdpaalpaekvsqaavdellkrgvvtkgdwviltkgdsytaqggtntmkvlhvgd
llv