PDB entry 6qxa

View 6qxa on RCSB PDB site
Description: structure of membrane bound pyrophosphatase from thermotoga maritima in complex with imidodiphosphate and n-[(2-amino-6-benzothiazolyl) methyl]-1h-indole-2-carboxamide (atc)
Deposited on 2019-03-07, released 2019-04-10
The last revision was dated 2019-06-05, with a file datestamp of 2019-05-30.
Experiment type: XRAY
Resolution: 3.41 Å
R-factor: N/A
AEROSPACI score: 0.1 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: k(+)-stimulated pyrophosphate-energized sodium pump
    Species: THERMOTOGA MARITIMA MSB8 [TaxId:243274]
    Gene: hppA, TM_0174
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q9S5X0 (10-734)
      • conflict (361)
      • conflict (403)
  • Chain 'B':
    Compound: k(+)-stimulated pyrophosphate-energized sodium pump
    Species: THERMOTOGA MARITIMA MSB8 [TaxId:243274]
    Gene: hppA, TM_0174
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q9S5X0 (10-734)
      • conflict (361)
      • conflict (403)
  • Chain 'C':
    Compound: k(+)-stimulated pyrophosphate-energized sodium pump
    Species: THERMOTOGA MARITIMA MSB8 [TaxId:243274]
    Gene: hppA, TM_0174
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q9S5X0 (10-734)
      • conflict (361)
      • conflict (403)
  • Chain 'D':
    Compound: k(+)-stimulated pyrophosphate-energized sodium pump
    Species: THERMOTOGA MARITIMA MSB8 [TaxId:243274]
    Gene: hppA, TM_0174
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q9S5X0 (10-734)
      • conflict (361)
      • conflict (403)
  • Heterogens: MG, 2PN, NA, K, GQB, D1D, HOH

PDB Chain Sequences:
This PDB entry is not classified in SCOPe 2.08, so the chain sequences below are not included in the ASTRAL sequence sets.

  • Chain 'A':
    Sequence, based on SEQRES records:
    >6qxaA (A:)
mrgshhhhhhyvaalffliplvalgfaaanfaavvrkpegtermkeissyirsgadsfla
hetkaifkvaiviaillmifttwqtgvafllgavmsasagivgmkmatranvrvaeaart
tkkigpalkvayqggsvmglsvggfallglvlvylifgkwmgqvdnlniytnwlginfvp
famtvsgyalgcsiiamfdrvgggvytkaadmaadlvgktelnlpeddprnpatiadnvg
dnvgdvaglgadllesfvgaivssiilasymfpiyvqkigenlvhqvpketiqalisypi
ffalvglgcsmlgilyvivkkpsdnpqrelnislwtsalltvvltafltyfylkdlqgld
vlgfrfgaispwfsaiigifsgiligfwaeyytsyrykptqflgkssiegtgmvisngls
lgmksvfpptltlvlgilfadyfaglygvaiaalgmlsfvatsvsvdsygpiadnaggis
emceldpevrkitdhldavgnttaaigkgfaigsaifaalslfasymfsqispsdigkpp
slvlllnmldarviagallgaaityyfsgylisavtkaamkmvdeirrqareipgllegk
akpdynrcieitsdnalkqmgypafiailtplvtgfllgaefvggvligtvlsgamlail
tansggawdnakkyleagnlegygkgsephkalvigdtvgdplkdtvgpsldilikimsv
vsviavsifkhvhlf

    Sequence, based on observed residues (ATOM records):
    >6qxaA (A:)
yvaalffliplvalgfaaanfaavvrkpegtermkeissyirsgadsflahetkaifkva
iviaillmifttwqtgvafllgavmsasagivgmkmatranvrvaeaarttkkigpalkv
ayqggsvmglsvggfallglvlvylifgkwmgqvdnlniytnwlginfvpfamtvsgyal
gcsiiamfdrvgggvytkaadmaadlvgktelnlpeddprnpatiadnvgdnvgdvaglg
adllesfvgaivssiilasymfpiyvqkigenlvhqvpketiqalisypiffalvglgcs
mlgilyvivkkpsdnpqrelnislwtsalltvvltafltyfylkdlqgldvlgfrfgais
pwfsaiigifsgiligfwaeyytsyrykptqflgkssiegtgmvisnglslgmksvfppt
ltlvlgilfadyfaglygvaiaalgmlsfvatsvsvdsygpiadnaggisemceldpevr
kitdhldavgnttaaigkgfaigsaifaalslfasymfsqispsdigkppslvlllnmld
arviagallgaaityyfsgylisavtkaamkmvdeirrqareipgllegkakpdynrcie
itsdnalkqmgypafiailtplvtgfllgaefvggvligtvlsgamlailtansggawdn
akkyleagnlegygkgsephkalvigdtvgdplkdtvgpsldilikimsvvsviavsifk
hvhlf

  • Chain 'B':
    Sequence, based on SEQRES records:
    >6qxaB (B:)
mrgshhhhhhyvaalffliplvalgfaaanfaavvrkpegtermkeissyirsgadsfla
hetkaifkvaiviaillmifttwqtgvafllgavmsasagivgmkmatranvrvaeaart
tkkigpalkvayqggsvmglsvggfallglvlvylifgkwmgqvdnlniytnwlginfvp
famtvsgyalgcsiiamfdrvgggvytkaadmaadlvgktelnlpeddprnpatiadnvg
dnvgdvaglgadllesfvgaivssiilasymfpiyvqkigenlvhqvpketiqalisypi
ffalvglgcsmlgilyvivkkpsdnpqrelnislwtsalltvvltafltyfylkdlqgld
vlgfrfgaispwfsaiigifsgiligfwaeyytsyrykptqflgkssiegtgmvisngls
lgmksvfpptltlvlgilfadyfaglygvaiaalgmlsfvatsvsvdsygpiadnaggis
emceldpevrkitdhldavgnttaaigkgfaigsaifaalslfasymfsqispsdigkpp
slvlllnmldarviagallgaaityyfsgylisavtkaamkmvdeirrqareipgllegk
akpdynrcieitsdnalkqmgypafiailtplvtgfllgaefvggvligtvlsgamlail
tansggawdnakkyleagnlegygkgsephkalvigdtvgdplkdtvgpsldilikimsv
vsviavsifkhvhlf

    Sequence, based on observed residues (ATOM records):
    >6qxaB (B:)
yvaalffliplvalgfaaanfaavvrkpegtermkeissyirsgadsflahetkaifkva
iviaillmifttwqtgvafllgavmsasagivgmkmatranvrvaeaarttkkigpalkv
ayqggsvmglsvggfallglvlvylifgkwmgqvdnlniytnwlginfvpfamtvsgyal
gcsiiamfdrvgggvytkaadmaadlvgktelnlpeddprnpatiadnvgdnvgdvaglg
adllesfvgaivssiilasymfpiyvqvhqvpketiqalisypiffalvglgcsmlgily
vivkkpsdnpqrelnislwtsalltvvltafltyfylkldvlgfrfgaispwfsaiigif
sgiligfwaeyytsyrykptqflgkssiegtgmvisnglslgmksvfpptltlvlgilfa
dyfaglygvaiaalgmlsfvatsvsvdsygpiadnaggisemceldpevrkitdhldavg
nttaaigkgfaigsaifaalslfasymfsqispsdigkppslvlllnmldarviagallg
aaityyfsgylisavtkaamkmvdeirrqareipgllegkakpdynrcieitsdnalkqm
gypafiailtplvtgfllgaefvggvligtvlsgamlailtansggawdnakkyleagnl
egygkgsephkalvigdtvgdplkdtvgpsldilikimsvvsviavsifkhvhlf

  • Chain 'C':
    Sequence, based on SEQRES records:
    >6qxaC (C:)
mrgshhhhhhyvaalffliplvalgfaaanfaavvrkpegtermkeissyirsgadsfla
hetkaifkvaiviaillmifttwqtgvafllgavmsasagivgmkmatranvrvaeaart
tkkigpalkvayqggsvmglsvggfallglvlvylifgkwmgqvdnlniytnwlginfvp
famtvsgyalgcsiiamfdrvgggvytkaadmaadlvgktelnlpeddprnpatiadnvg
dnvgdvaglgadllesfvgaivssiilasymfpiyvqkigenlvhqvpketiqalisypi
ffalvglgcsmlgilyvivkkpsdnpqrelnislwtsalltvvltafltyfylkdlqgld
vlgfrfgaispwfsaiigifsgiligfwaeyytsyrykptqflgkssiegtgmvisngls
lgmksvfpptltlvlgilfadyfaglygvaiaalgmlsfvatsvsvdsygpiadnaggis
emceldpevrkitdhldavgnttaaigkgfaigsaifaalslfasymfsqispsdigkpp
slvlllnmldarviagallgaaityyfsgylisavtkaamkmvdeirrqareipgllegk
akpdynrcieitsdnalkqmgypafiailtplvtgfllgaefvggvligtvlsgamlail
tansggawdnakkyleagnlegygkgsephkalvigdtvgdplkdtvgpsldilikimsv
vsviavsifkhvhlf

    Sequence, based on observed residues (ATOM records):
    >6qxaC (C:)
yvaalffliplvalgfaaanfaavvrkpegtermkeissyirsgadsflahetkaifkva
iviaillmifttwqtgvafllgavmsasagivgmkmatranvrvaeaarttkkigpalkv
ayqggsvmglsvggfallglvlvylifgkwmgqvdnlniytnwlginfvpfamtvsgyal
gcsiiamfdrvgggvytkaadmaadlvgktelnlpeddprnpatiadnvgdnvgdvaglg
adllesfvgaivssiilasymfpiyvqkigenlvhqvpketiqalisypiffalvglgcs
mlgilyvivkkpsdnpqrelnislwtsalltvvltafltyfylkdlqgldvlgfrfgais
pwfsaiigifsgiligfwaeyytsyrykptqflgkssiegtgmvisnglslgmksvfppt
ltlvlgilfadyfaglygvaiaalgmlsfvatsvsvdsygpiadnaggisemceldpevr
kitdhldavgnttaaigkgfaigsaifaalslfasymfsqispsdigkppslvlllnmld
arviagallgaaityyfsgylisavtkaamkmvdeirrqareipgllegkakpdynrcie
itsdnalkqmgypafiailtplvtgfllgaefvggvligtvlsgamlailtansggawdn
akkyleagnlegygkgsephkalvigdtvgdplkdtvgpsldilikimsvvsviavsifk
hvhlf

  • Chain 'D':
    Sequence, based on SEQRES records:
    >6qxaD (D:)
mrgshhhhhhyvaalffliplvalgfaaanfaavvrkpegtermkeissyirsgadsfla
hetkaifkvaiviaillmifttwqtgvafllgavmsasagivgmkmatranvrvaeaart
tkkigpalkvayqggsvmglsvggfallglvlvylifgkwmgqvdnlniytnwlginfvp
famtvsgyalgcsiiamfdrvgggvytkaadmaadlvgktelnlpeddprnpatiadnvg
dnvgdvaglgadllesfvgaivssiilasymfpiyvqkigenlvhqvpketiqalisypi
ffalvglgcsmlgilyvivkkpsdnpqrelnislwtsalltvvltafltyfylkdlqgld
vlgfrfgaispwfsaiigifsgiligfwaeyytsyrykptqflgkssiegtgmvisngls
lgmksvfpptltlvlgilfadyfaglygvaiaalgmlsfvatsvsvdsygpiadnaggis
emceldpevrkitdhldavgnttaaigkgfaigsaifaalslfasymfsqispsdigkpp
slvlllnmldarviagallgaaityyfsgylisavtkaamkmvdeirrqareipgllegk
akpdynrcieitsdnalkqmgypafiailtplvtgfllgaefvggvligtvlsgamlail
tansggawdnakkyleagnlegygkgsephkalvigdtvgdplkdtvgpsldilikimsv
vsviavsifkhvhlf

    Sequence, based on observed residues (ATOM records):
    >6qxaD (D:)
yvaalffliplvalgfaaanfaavvrkpegtermkeissyirsgadsflahetkaifkva
iviaillmifttwqtgvafllgavmsasagivgmkmatranvrvaeaarttkkigpalkv
ayqggsvmglsvggfallglvlvylifgkwmgqvdnlniytnwlginfvpfamtvsgyal
gcsiiamfdrvgggvytkaadmaadlvgktelnlpeddprnpatiadnvgdnvgdvaglg
adllesfvgaivssiilasymfpiyvqvhqvpketiqalisypiffalvglgcsmlgily
vivkkpsdnpqrelnislwtsalltvvltafltyfylkdlqgldvlgfrfgaispwfsai
igifsgiligfwaeyytsyrykptqflgkssiegtgmvisnglslgmksvfpptltlvlg
ilfadyfaglygvaiaalgmlsfvatsvsvdsygpiadnaggisemceldpevrkitdhl
davgnttaaigkgfaigsaifaalslfasymfsqispsdigkppslvlllnmldarviag
allgaaityyfsgylisavtkaamkmvdeirrqareipgllegkakpdynrcieitsdna
lkqmgypafiailtplvtgfllgaefvggvligtvlsgamlailtansggawdnakkyle
agnlegygkgsephkalvigdtvgdplkdtvgpsldilikimsvvsviavsifkhvhlf