PDB entry 6qx8

View 6qx8 on RCSB PDB site
Description: influenza a virus (a/nt/60/1968) polymerase dimer of heterotrimer in complex with 5' crna promoter
Deposited on 2019-03-07, released 2019-09-04
The last revision was dated 2020-11-18, with a file datestamp of 2020-11-13.
Experiment type: EM
Resolution: 4.07 Å
R-factor: N/A
AEROSPACI score: 0.1 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Polymerase acidic protein
    Species: Influenza A virus (strain A/Northern Territory/60/1968 H3N2) [TaxId:384505]
    Gene: PA
    Database cross-references and differences (RAF-indexed):
  • Chain 'B':
    Compound: RNA-directed RNA polymerase catalytic subunit
    Species: Influenza A virus (strain A/Northern Territory/60/1968 H3N2) [TaxId:384505]
    Gene: Pb1
    Database cross-references and differences (RAF-indexed):
    • Uniprot P03432 (0-End)
      • conflict (576)
  • Chain 'C':
    Compound: Polymerase basic protein 2
    Species: Influenza A virus (strain A/Northern Territory/60/1968 H3N2) [TaxId:384505]
    Gene: pb2
    Database cross-references and differences (RAF-indexed):
  • Chain 'D':
    Compound: RNA (5'-r(p*ap*gp*cp*ap*ap*ap*ap*gp*cp*ap*gp*a)-3')
    Species: Influenza A virus (A/nt/60/1968(H3N2)), synthetic [TaxId:384505]
  • Chain 'E':
    Compound: Polymerase acidic protein
    Species: Influenza A virus (strain A/Northern Territory/60/1968 H3N2) [TaxId:384505]
    Gene: PA
    Database cross-references and differences (RAF-indexed):
  • Chain 'F':
    Compound: RNA-directed RNA polymerase catalytic subunit
    Species: Influenza A virus (strain A/Northern Territory/60/1968 H3N2) [TaxId:384505]
    Gene: Pb1
    Database cross-references and differences (RAF-indexed):
    • Uniprot P03432 (0-End)
      • conflict (576)
  • Chain 'G':
    Compound: Polymerase basic protein 2
    Species: Influenza A virus (strain A/Northern Territory/60/1968 H3N2) [TaxId:384505]
    Gene: pb2
    Database cross-references and differences (RAF-indexed):
  • Chain 'H':
    Compound: RNA (5'-r(p*ap*gp*cp*ap*ap*ap*ap*gp*cp*ap*gp*a)-3')
    Species: Influenza A virus (A/nt/60/1968(H3N2)), synthetic [TaxId:384505]

PDB Chain Sequences:
This PDB entry is not classified in SCOPe 2.08, so the chain sequences below are not included in the ASTRAL sequence sets.

  • Chain 'A':
    Sequence, based on SEQRES records:
    >6qx8A (A:)
medfvrqcfnpmivelaekamkeygedlkietnkfaaicthlevcfmysdfhfineqges
ivvelddpnallkhrfeiiegrdrtmawtvvnsicnttgaekpkflpdlydykenrfiei
gvtrrevhiyylekankiksenthihifsftgeematkadytldeesrariktrlftirq
emanrglwdsfrqsergeetieerfeitgtmrrladqslppnfsclenfrayvdgfepng
yiegklsqmskevnakiepflkttprpirlpdgppcfqrskfllmdalklsiedpshege
giplydaikcmrtffgwkepyivkphekginpnyllswkqvlaelqdieneekiprtknm
kktsqlkwalgenmapekvdfdncrdvsdlkqydsdepelrslsswiqnefnkaceltds
twieldeigedvapieyiasmrrnyftaevshcrateyimkgvyintallnascaamddf
qlipmiskcrtkegrrktnlygfiikgrshlrndtdvvnfvsmefsltdprlephkweky
cvleigdmllrsaigqmsrpmflyvrtngtskikmkwgmemrrcllqslqqiesmieaes
svkekdmtkeffenksetwpigespkgvedgsigkvcrtllaksvfnslyaspqlegfsa
esrklllvvqalrdnlepgtfdleglyeaieeclindpwvllnaswfnsflthalr

    Sequence, based on observed residues (ATOM records):
    >6qx8A (A:)
erfeitgtmrrladqslppnfsclenfrayvdgfepngyiegklsqmskevnakiepflk
ttprpirlpdgppcfqrskfllmdalklsiedpshegegiplydaikcmrtffgwkepyi
vkphekginpnyllswkqvlaelqdieneekiprtknmkktsqlkwalgenmapekvdfd
ncrdvsdlkqydsdepelrslsswiqnefnkaceltdstwieldeigedvapieyiasmr
rnyftaevshcrateyimkgvyintallnascaamddfqlipmiskcrtkegrrktnlyg
fiikgrshlrndtdvvnfvsmefsltdprlephkwekycvleigdmllrsaigqmsrpmf
lyvrtngtskikmkwgmemrrcllqslqqiesmieaessvkekdmtkeffenksetwpig
espkgvedgsigkvcrtllaksvfnslyaspqlegfsaesrklllvvqalrdnlepgtfd
leglyeaieeclindpwvllnaswfnsflthalr

  • Chain 'B':
    Sequence, based on SEQRES records:
    >6qx8B (B:)
mdvnptllflkvpaqnaisttfpytgdppyshgtgtgytmdtvnrthqysekgkwttnte
tgapqlnpidgplpednepsgyaqtdcvleamafleeshpgifenscletmevvqqtrvd
rltqgrqtydwtlnrnqpaatalantievfrsngltanesgrlidflkdvmesmdkeeme
itthfqrkrrvrdnmtkkmvtqrtigkkkqrvnkrsyliraltlntmtkdaergklkrra
iatpgmqirgfvyfvetlarsicekleqsglpvggnekkaklanvvrkmmtnsqdtelsf
titgdntkwnenqnprmflamityitknqpewfrnvlsiapimfsnkmarlgkgymfesk
smklrtqipaemlasidlkyfnestrkkiekirpllidgtaslspgmmmgmfnmlstvlg
vsilnlgqkrytkttywwdglqssddfalivnapnhegiqagvdrfyrtcklvginmskk
ksyinrtgtfeftsffyrygfvanfsmelpsfgvsginesadmsigvtviknnminndlg
pataqmalqlfikdyrytyrchrgdtqiqtrrsfelkklweqtrskagllvsdggpnlyn
irnlhipevclkwelmdedyqgrlcnplnpfvshkeiesvnnavvmpahgpaksmeydav
atthswipkrnrsilntsqrgiledeqmyqkccnlfekffpsssyrrpvgissmveamvs
raridaridfesgrikkeefaeimkicstieelrrqk

    Sequence, based on observed residues (ATOM records):
    >6qx8B (B:)
mdvnptllflkvpaqnaisttfpytgdppyshgtgtgytmdtvnrthqysekgkwttnte
tgapqlnpidgplpednepsgyaqtdcvleamafleeshpgifenscletmevvqqtrvd
rltqgrqtydwtlnrnqpaatalantievfrsngltanesgrlidflkdvmesmdkeemr
vnkrsyliraltlntmtkdaergklkrraiatpgmqirgfvyfvetlarsicekleqsgl
pvggnekkaklanvvrkmmtnsqdtelsftitgdntkwnenqnprmflamityitknqpe
wfrnvlsiapimfsnkmarlgkgymfesksmklrtqipaemlasidlkyfnestrkkiek
irpllidgtaslspgmmmgmfnmlstvlgvsilnlgqkrytkttywwdglqssddfaliv
napnhegiqagvdrfyrtcklvginmskkksyinrtgtfeftsffyrygfvanfsmelps
fgvsginesadmsigvtviknnminndlgpataqmalqlfikdyrytyrchrgdtqiqtr
rsfelkklweqtrskagllvsdggpnlynirnlhipevclkwelmdedyqgrlcnplnpf
vtthswipkrn

  • Chain 'C':
    Sequence, based on SEQRES records:
    >6qx8C (C:)
merikelrnlmsqsrtreiltkttvdhmaiikkytsgrqeknpslrmkwmmamkypitad
kritemvperneqgqtlwskmsdagsdrvmvsplavtwwnrngpmtstvhypkvyktyfe
kverlkhgtfgpvhfrnqvkirrrvdinpghadlsakeaqdvimevvfpnevgariltse
sqltitkekkeelqdckisplmvaymlerelvrktrflpvaggtssvyievlhltqgtcw
eqmytpggevrnddvdqsliiaarnivrraavsadplasllemchstqiggtrmvdilrq
npteeqavdickaamglrisssfsfggftfkrtsgssikreeelltgnlqtlkirvhdgy
eeftmvgkratailrkatrrlvqlivsgrdeqsvaeaiivamvfsqedcmikavrgdlnf
vnranqrlnpmhqllrhfqkdakvlfqnwgiehidnvmgmigvlpdmtpstemsmrgirv
skmgvdeysstervvvsidrflrvrdqrgnvllspeevsetqgtekltitysssmmwein
gpesvlvntyqwiirnwetvkiqwsqnptmlynkmefepfqslvpkairgqysgfvrtlf
qqmrdvlgtfdttqiikllpfaaappkqsrmqfssltvnvrgsgmrilvrgnspafnynk
ttkrltilgkdagtliedpdegtsgvesavlrgflilgkedrrygpalsinelsnlakge
kanvligqgdvvlvmkrkrdssiltdsqtatkrirmain

    Sequence, based on observed residues (ATOM records):
    >6qx8C (C:)
kypitadkritemvperneqgqtlwskmrvmvsplavtwwnrngpmtstvhypkvyktyf
ekverlk

  • Chain 'D':
    No sequence available.

  • Chain 'E':
    Sequence, based on SEQRES records:
    >6qx8E (E:)
medfvrqcfnpmivelaekamkeygedlkietnkfaaicthlevcfmysdfhfineqges
ivvelddpnallkhrfeiiegrdrtmawtvvnsicnttgaekpkflpdlydykenrfiei
gvtrrevhiyylekankiksenthihifsftgeematkadytldeesrariktrlftirq
emanrglwdsfrqsergeetieerfeitgtmrrladqslppnfsclenfrayvdgfepng
yiegklsqmskevnakiepflkttprpirlpdgppcfqrskfllmdalklsiedpshege
giplydaikcmrtffgwkepyivkphekginpnyllswkqvlaelqdieneekiprtknm
kktsqlkwalgenmapekvdfdncrdvsdlkqydsdepelrslsswiqnefnkaceltds
twieldeigedvapieyiasmrrnyftaevshcrateyimkgvyintallnascaamddf
qlipmiskcrtkegrrktnlygfiikgrshlrndtdvvnfvsmefsltdprlephkweky
cvleigdmllrsaigqmsrpmflyvrtngtskikmkwgmemrrcllqslqqiesmieaes
svkekdmtkeffenksetwpigespkgvedgsigkvcrtllaksvfnslyaspqlegfsa
esrklllvvqalrdnlepgtfdleglyeaieeclindpwvllnaswfnsflthalr

    Sequence, based on observed residues (ATOM records):
    >6qx8E (E:)
erfeitgtmrrladqslppnfsclenfrayvdgfepngyiegklsqmskevnakiepflk
ttprpirlpdgppcfqrskfllmdalklsiedpshegegiplydaikcmrtffgwkepyi
vkphekginpnyllswkqvlaelqdieneekiprtknmkktsqlkwalgenmapekvdfd
ncrdvsdlkqydsdepelrslsswiqnefnkaceltdstwieldeigedvapieyiasmr
rnyftaevshcrateyimkgvyintallnascaamddfqlipmiskcrtkegrrktnlyg
fiikgrshlrndtdvvnfvsmefsltdprlephkwekycvleigdmllrsaigqmsrpmf
lyvrtngtskikmkwgmemrrcllqslqqiesmieaessvkekdmtkeffenksetwpig
espkgvedgsigkvcrtllaksvfnslyaspqlegfsaesrklllvvqalrdnlepgtfd
leglyeaieeclindpwvllnaswfnsflthalr

  • Chain 'F':
    Sequence, based on SEQRES records:
    >6qx8F (F:)
mdvnptllflkvpaqnaisttfpytgdppyshgtgtgytmdtvnrthqysekgkwttnte
tgapqlnpidgplpednepsgyaqtdcvleamafleeshpgifenscletmevvqqtrvd
rltqgrqtydwtlnrnqpaatalantievfrsngltanesgrlidflkdvmesmdkeeme
itthfqrkrrvrdnmtkkmvtqrtigkkkqrvnkrsyliraltlntmtkdaergklkrra
iatpgmqirgfvyfvetlarsicekleqsglpvggnekkaklanvvrkmmtnsqdtelsf
titgdntkwnenqnprmflamityitknqpewfrnvlsiapimfsnkmarlgkgymfesk
smklrtqipaemlasidlkyfnestrkkiekirpllidgtaslspgmmmgmfnmlstvlg
vsilnlgqkrytkttywwdglqssddfalivnapnhegiqagvdrfyrtcklvginmskk
ksyinrtgtfeftsffyrygfvanfsmelpsfgvsginesadmsigvtviknnminndlg
pataqmalqlfikdyrytyrchrgdtqiqtrrsfelkklweqtrskagllvsdggpnlyn
irnlhipevclkwelmdedyqgrlcnplnpfvshkeiesvnnavvmpahgpaksmeydav
atthswipkrnrsilntsqrgiledeqmyqkccnlfekffpsssyrrpvgissmveamvs
raridaridfesgrikkeefaeimkicstieelrrqk

    Sequence, based on observed residues (ATOM records):
    >6qx8F (F:)
mdvnptllflkvpaqnaisttfpytgdppyshgtgtgytmdtvnrthqysekgkwttnte
tgapqlnpidgplpednepsgyaqtdcvleamafleeshpgifenscletmevvqqtrvd
rltqgrqtydwtlnrnqpaatalantievfrsngltanesgrlidflkdvmesmdkeemr
vnkrsyliraltlntmtkdaergklkrraiatpgmqirgfvyfvetlarsicekleqsgl
pvggnekkaklanvvrkmmtnsqdtelsftitgdntkwnenqnprmflamityitknqpe
wfrnvlsiapimfsnkmarlgkgymfesksmklrtqipaemlasidlkyfnestrkkiek
irpllidgtaslspgmmmgmfnmlstvlgvsilnlgqkrytkttywwdglqssddfaliv
napnhegiqagvdrfyrtcklvginmskkksyinrtgtfeftsffyrygfvanfsmelps
fgvsginesadmsigvtviknnminndlgpataqmalqlfikdyrytyrchrgdtqiqtr
rsfelkklweqtrskagllvsdggpnlynirnlhipevclkwelmdedyqgrlcnplnpf
vtthswipkrn

  • Chain 'G':
    Sequence, based on SEQRES records:
    >6qx8G (G:)
merikelrnlmsqsrtreiltkttvdhmaiikkytsgrqeknpslrmkwmmamkypitad
kritemvperneqgqtlwskmsdagsdrvmvsplavtwwnrngpmtstvhypkvyktyfe
kverlkhgtfgpvhfrnqvkirrrvdinpghadlsakeaqdvimevvfpnevgariltse
sqltitkekkeelqdckisplmvaymlerelvrktrflpvaggtssvyievlhltqgtcw
eqmytpggevrnddvdqsliiaarnivrraavsadplasllemchstqiggtrmvdilrq
npteeqavdickaamglrisssfsfggftfkrtsgssikreeelltgnlqtlkirvhdgy
eeftmvgkratailrkatrrlvqlivsgrdeqsvaeaiivamvfsqedcmikavrgdlnf
vnranqrlnpmhqllrhfqkdakvlfqnwgiehidnvmgmigvlpdmtpstemsmrgirv
skmgvdeysstervvvsidrflrvrdqrgnvllspeevsetqgtekltitysssmmwein
gpesvlvntyqwiirnwetvkiqwsqnptmlynkmefepfqslvpkairgqysgfvrtlf
qqmrdvlgtfdttqiikllpfaaappkqsrmqfssltvnvrgsgmrilvrgnspafnynk
ttkrltilgkdagtliedpdegtsgvesavlrgflilgkedrrygpalsinelsnlakge
kanvligqgdvvlvmkrkrdssiltdsqtatkrirmain

    Sequence, based on observed residues (ATOM records):
    >6qx8G (G:)
kypitadkritemvperneqgqtlwskmrvmvsplavtwwnrngpmtstvhypkvyktyf
ekverlk

  • Chain 'H':
    No sequence available.