PDB entry 6quu
View 6quu on RCSB PDB site
Description: Crystal Structure of KRAS-G12D in complex with GMP-PCP
Class: oncoprotein
Keywords: PPI, KRAS, GTPase, cancer, ONCOPROTEIN
Deposited on
2019-02-28, released
2019-07-31
The last revision prior to the SCOPe 2.08 freeze date was dated
2019-09-25, with a file datestamp of
2019-09-20.
Experiment type: XRAY
Resolution: 1.48 Å
R-factor: N/A
AEROSPACI score: 0.49
(click here for full SPACI score report)
Chains and heterogens:
- Chain 'A':
Compound: GTPase KRas
Species: Homo sapiens [TaxId:9606]
Gene: KRAS, KRAS2, RASK2
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.08: d6quua_ - Chain 'B':
Compound: GTPase KRas
Species: Homo sapiens [TaxId:9606]
Gene: KRAS, KRAS2, RASK2
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.08: d6quub_ - Heterogens: GCP, MG, HOH
PDB Chain Sequences:
- Chain 'A':
Sequence, based on SEQRES records: (download)
>6quuA (A:)
mhhhhhhssgrenlyfqgmteyklvvvgadgvgksaltiqliqnhfvdeydptiedsyrk
qvvidgetclldildtagqeeysamrdqymrtgegflcvfainntksfedihhyreqikr
vkdsedvpmvlvgnkcdlpsrtvdtkqaqdlarsygipfietsaktrqgvddafytlvre
irkhkek
Sequence, based on observed residues (ATOM records): (download)
>6quuA (A:)
mteyklvvvgadgvgksaltiqliqnhfvdeydptiedsyrkqvvidgetclldildtag
qeeysamrdqymrtgegflcvfainntksfedihhyreqikrvkdsedvpmvlvgnkcdl
psrtvdtkqaqdlarsygipfietsaktrqgvddafytlvreirkhk
- Chain 'B':
Sequence, based on SEQRES records: (download)
>6quuB (B:)
mhhhhhhssgrenlyfqgmteyklvvvgadgvgksaltiqliqnhfvdeydptiedsyrk
qvvidgetclldildtagqeeysamrdqymrtgegflcvfainntksfedihhyreqikr
vkdsedvpmvlvgnkcdlpsrtvdtkqaqdlarsygipfietsaktrqgvddafytlvre
irkhkek
Sequence, based on observed residues (ATOM records): (download)
>6quuB (B:)
mteyklvvvgadgvgksaltiqliqnhfvdeydptiedsyrkqvvidgetclldildtag
qeeysamrdqymrtgegflcvfainntksfedihhyreqikrvkdsedvpmvlvgnkcdl
psrtvdtkqaqdlarsygipfietsaktrqgvddafytlvreirkhk