PDB entry 6qtk

View 6qtk on RCSB PDB site
Description: 2.31a structure of gepotidacin with s.aureus dna gyrase and doubly nicked dna
Deposited on 2019-02-25, released 2019-03-13
The last revision was dated 2019-04-24, with a file datestamp of 2019-04-19.
Experiment type: XRAY
Resolution: 2.31 Å
R-factor: N/A
AEROSPACI score: 0.25 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: DNA gyrase subunit A
    Species: Staphylococcus aureus [TaxId:1280]
    Gene: gyrA, SA0006
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q99XG5 (Start-489)
      • conflict (121)
  • Chain 'B':
    Compound: DNA gyrase subunit b
    Species: Staphylococcus aureus (strain N315) [TaxId:158879]
    Gene: gyrB, SA0005
    Database cross-references and differences (RAF-indexed):
    • Uniprot P66937
      • conflict (135-136)
  • Chain 'C':
    Compound: DNA gyrase subunit A
    Species: Staphylococcus aureus [TaxId:1280]
    Gene: gyrA, SA0006
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q99XG5
      • conflict (121)
  • Chain 'D':
    Compound: DNA gyrase subunit b
    Species: Staphylococcus aureus (strain N315) [TaxId:158879]
    Gene: gyrB, SA0005
    Database cross-references and differences (RAF-indexed):
    • Uniprot P66937
      • conflict (135-136)
  • Chain 'E':
    Compound: DNA (5'-d(*ap*gp*cp*cp*gp*tp*ap*g*gp*gp*tp*ap*cp*cp*tp*ap*cp*gp*gp*cp*t)-3')
    Species: synthetic construct, synthetic [TaxId:32630]
  • Chain 'F':
    Compound: DNA (5'-d(*ap*gp*cp*cp*gp*tp*ap*g*gp*gp*tp*ap*cp*cp*tp*ap*cp*gp*gp*cp*t)-3')
    Species: synthetic construct, synthetic [TaxId:32630]
  • Heterogens: JHN, MN, GOL, NA, HOH

PDB Chain Sequences:
This PDB entry is not classified in SCOPe 2.08, so the chain sequences below are not included in the ASTRAL sequence sets.

  • Chain 'A':
    Sequence, based on SEQRES records:
    >6qtkA (A:)
aelpqsrinernitsemresfldyamsvivaralpdvrdglkpvhrrilyglneqgmtpd
ksykksarivgdvmgkyhphgdssiyeamvrmaqdfsyryplvdgqgnfgsmdgdgaaam
rftearmtkitlellrdinkdtidfidnydgnerepsvlparfpnllangasgiavgmat
nipphnltelingvlslsknpdisiaelmediegpdfptaglilgksgirrayetgrgsi
qmrsravieergggrqrivvteipfqvnkarmiekiaelvrdkkidgitdlrdetslrtg
vrvvidvrkdanasvilnnlykqtplqtsfgvnmialvngrpklinlkealvhylehqkt
vvrrrtqynlrkakdrahileglrialdhideiistiresdtdkvameslqqrfklsekq
aqaildmrlrrltglerdkieaeynellnyiseletiladeevllqlvrdelteirdrfg
ddrrteiqlg

    Sequence, based on observed residues (ATOM records):
    >6qtkA (A:)
rinernitsemresfldyamsvivaralpdvrdglkpvhrrilyglneqgmtpdksykks
arivgdvmgkyhphgdssiyeamvrmaqdfsyryplvdgqgnfgsmdgdgaaamrftear
mtkitlellrdinkdtidfidnydgnerepsvlparfpnllangasgiavgmatnipphn
ltelingvlslsknpdisiaelmediegpdfptaglilgksgirrayetgrgsiqmrsra
vieergggrqrivvteipfqvnkarmiekiaelvrdkkidgitdlrdetslrtgvrvvid
vrkdanasvilnnlykqtplqtsfgvnmialvngrpklinlkealvhylehqktvvrrrt
qynlrkakdrahileglrialdhideiistiresdtdkvameslqqrfklsekqaqaild
mrlrrltglerdkieaeynellnyiseletiladeevllqlvrdelteirdrfgddrrte
iqlg

  • Chain 'B':
    Sequence, based on SEQRES records:
    >6qtkB (B:)
mdvaslpgkladcsskspeeceiflvegdsaggstksgrdsrtqailplrgkilnvekar
ldrilnnneirqmitafgtgiggdfdlakaryhkivimtdadvdgahirtllltffyrfm
rplieagyvyiaqpptgykglgemnadqlwettmnpehrallqvkledaieadqtfemlm
gdvvenrrqfiednavyanldf

    Sequence, based on observed residues (ATOM records):
    >6qtkB (B:)
pgkladcsskspeeceiflvegdsaggstksgrdsrtqailplrgkilnvekarldriln
nneirqmitafgtgiggdfdlakaryhkivimtdadvdgahirtllltffyrfmrpliea
gyvyiaqpptgykglgemnadqlwettmnpehrallqvkledaieadqtfemlmgdvven
rrqfiednavya

  • Chain 'C':
    Sequence, based on SEQRES records:
    >6qtkC (C:)
aelpqsrinernitsemresfldyamsvivaralpdvrdglkpvhrrilyglneqgmtpd
ksykksarivgdvmgkyhphgdssiyeamvrmaqdfsyryplvdgqgnfgsmdgdgaaam
rftearmtkitlellrdinkdtidfidnydgnerepsvlparfpnllangasgiavgmat
nipphnltelingvlslsknpdisiaelmediegpdfptaglilgksgirrayetgrgsi
qmrsravieergggrqrivvteipfqvnkarmiekiaelvrdkkidgitdlrdetslrtg
vrvvidvrkdanasvilnnlykqtplqtsfgvnmialvngrpklinlkealvhylehqkt
vvrrrtqynlrkakdrahileglrialdhideiistiresdtdkvameslqqrfklsekq
aqaildmrlrrltglerdkieaeynellnyiseletiladeevllqlvrdelteirdrfg
ddrrteiqlg

    Sequence, based on observed residues (ATOM records):
    >6qtkC (C:)
inernitsemresfldyamsvivaralpdvrdglkpvhrrilyglneqgmtpdksykksa
rivgdvmgkyhphgdssiyeamvrmaqdfsyryplvdgqgnfgsmdgdgaaamrftearm
tkitlellrdinkdtidfidnydgnerepsvlparfpnllangasgiavgmatnipphnl
telingvlslsknpdisiaelmediegpdfptaglilgksgirrayetgrgsiqmrsrav
ieergggrqrivvteipfqvnkarmiekiaelvrdkkidgitdlrdetslrtgvrvvidv
rkdanasvilnnlykqtplqtsfgvnmialvngrpklinlkealvhylehqktvvrrrtq
ynlrkakdrahileglrialdhideiistiresdtdkvameslqqrfklsekqaqaildm
rlrrltglerdkieaeynellnyiseletiladeevllqlvrdelteirdrfgddrrtei
ql

  • Chain 'D':
    Sequence, based on SEQRES records:
    >6qtkD (D:)
mdvaslpgkladcsskspeeceiflvegdsaggstksgrdsrtqailplrgkilnvekar
ldrilnnneirqmitafgtgiggdfdlakaryhkivimtdadvdgahirtllltffyrfm
rplieagyvyiaqpptgykglgemnadqlwettmnpehrallqvkledaieadqtfemlm
gdvvenrrqfiednavyanldf

    Sequence, based on observed residues (ATOM records):
    >6qtkD (D:)
pgkladcsskspeeceiflvegdsaggstksgrdsrtqailplrgkilnvekarldriln
nneirqmitafgtgiggdfdlakaryhkivimtdadvdgahirtllltffyrfmrpliea
gyvyiaqpptgykglgemnadqlwettmnpehrallqvkledaieadqtfemlmgdvven
rrqfiednavya

  • Chain 'E':
    No sequence available.

  • Chain 'F':
    No sequence available.