PDB entry 6qrf

View 6qrf on RCSB PDB site
Description: Crystal structure of TrmD, a tRNA-(N1G37) methyltransferase, from Mycobacterium abscessus in complex with inhibitor
Class: transferase
Keywords: TrmD, tRNA methyltransferase, SPOUT methyltransferase, TRANSFERASE
Deposited on 2019-02-19, released 2019-09-18
The last revision prior to the SCOPe 2.08 freeze date was dated 2019-09-18, with a file datestamp of 2019-09-13.
Experiment type: XRAY
Resolution: 1.86 Å
R-factor: N/A
AEROSPACI score: 0.35 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: tRNA (guanine-N(1)-)-methyltransferase
    Species: Mycobacterium abscessus [TaxId:36809]
    Gene: trmD, MAB_3226c
    Database cross-references and differences (RAF-indexed):
    • Uniprot B1MDI3 (2-End)
      • expression tag (1)
    Domains in SCOPe 2.08: d6qrfa1, d6qrfa2
  • Chain 'B':
    Compound: tRNA (guanine-N(1)-)-methyltransferase
    Species: Mycobacterium abscessus [TaxId:36809]
    Gene: trmD, MAB_3226c
    Database cross-references and differences (RAF-indexed):
    • Uniprot B1MDI3 (2-End)
      • expression tag (1)
    Domains in SCOPe 2.08: d6qrfb1, d6qrfb2
  • Heterogens: JF5, SO4, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >6qrfA (A:)
gsmkidvvtifpeylqpvrqslpgkaidaglvdvavhdlrrwthdvhksvddspygggpg
mvmkptvwgdaldeictsetllvvptpagypftqetawqwstedhlviacgryegidqrv
addaatrmrvrevsigdyvlnggeaaalviieavlrlvpgvlgnalsaqedshsegmasl
legpsytrppswrgmdvppvllsgdhakiaawraeqsrqrtierrpdllgfdsptgehgg
dgls

    Sequence, based on observed residues (ATOM records): (download) 
    >6qrfA (A:)
smkidvvtifpeylqpvrqslpgkaidaglvdvavhdlrrwthdvhksvddspygggpgm
vmkptvwgdaldeictsetllvvptpagypftqetawqwstedhlviacgryegidqrva
ddaatrmrvrevsigdyvlnggeaaalviieavlrlvpgvlgsllegpsytrppswrgmd
vppvllsgdhakiaawraeqsrqrtierrpdll

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >6qrfB (B:)
gsmkidvvtifpeylqpvrqslpgkaidaglvdvavhdlrrwthdvhksvddspygggpg
mvmkptvwgdaldeictsetllvvptpagypftqetawqwstedhlviacgryegidqrv
addaatrmrvrevsigdyvlnggeaaalviieavlrlvpgvlgnalsaqedshsegmasl
legpsytrppswrgmdvppvllsgdhakiaawraeqsrqrtierrpdllgfdsptgehgg
dgls

    Sequence, based on observed residues (ATOM records): (download) 
    >6qrfB (B:)
smkidvvtifpeylqpvdaglvdvavhdlrrwtksvddspygggpgmvmkptvwgdalde
ictsetllvvptpagypftqetawqwstedhlviacgryegidqrvaddaatrmrvrevs
igdyvlnggeaaalviieavlrlvpgvasllegpsytrppswrgmdvppvllsgdhakia
awraeqsrqrtierrpdllgfdsp