PDB entry 6qpw

View 6qpw on RCSB PDB site
Description: structural basis of cohesin ring opening
Deposited on 2019-02-15, released 2020-02-05
The last revision was dated 2020-03-18, with a file datestamp of 2020-03-13.
Experiment type: EM
Resolution: 3.3 Å
R-factor: N/A
AEROSPACI score: 0.1 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Structural maintenance of chromosomes protein,Structural maintenance of chromosomes protein
    Species: Chaetomium thermophilum var. thermophilum DSM 1495 [TaxId:759272]
    Gene: CTHT_0066330
    Database cross-references and differences (RAF-indexed):
  • Chain 'B':
    Compound: sister chromatid cohesion protein 1
    Species: SACCHAROMYCES CEREVISIAE S288C [TaxId:559292]
    Gene: MCD1, PDS3, RHC21, SCC1, YDL003W, YD8119.04
    Database cross-references and differences (RAF-indexed):
  • Chain 'C':
    Compound: Structural maintenance of chromosomes protein 3,Structural maintenance of chromosomes protein 3
    Species: SACCHAROMYCES CEREVISIAE S288C [TaxId:559292]
    Gene: SMC3, YJL074C, J1049
    Database cross-references and differences (RAF-indexed):
    • Uniprot P47037 (2-End)
    • Uniprot P47037
      • engineered mutation (463)
      • engineered mutation (508)
  • Chain 'E':
    Compound: Sister chromatid cohesion protein 1,Structural maintenance of chromosomes protein
    Species: Chaetomium thermophilum var. thermophilum DSM 1495 [TaxId:759272]
    Gene: CTHT_0066330
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q12158
    • Uniprot G0SGH3 (Start-365)
      • engineered mutation (261)
      • engineered mutation (302)
      • expression tag (366-367)
  • Heterogens: AGS, MG

PDB Chain Sequences:
This PDB entry is not classified in SCOPe 2.08, so the chain sequences below are not included in the ASTRAL sequence sets.

  • Chain 'A':
    Sequence, based on SEQRES records:
    >6qpwA (A:)
mgklirlelfnfksykghhtllfgdsyftsiigpngsgksnsmdaisfvlgiksshlrss
nlrdliyrgrvmktskiqddgttapatngdvngyengdagddedtsqrtsrndpktawvm
avyeddagelhrwkrtitangtseyrindrvvnaqqynealekenilikarnflvfqgdv
eaiasqspqdltrlieqisgsleykeeyerleeevrqateeqayklqrrraanseikqym
eq

    Sequence, based on observed residues (ATOM records):
    >6qpwA (A:)
gklirlelfnfksykghhtllfgdsyftsiigpngsgksnsmdaisfvlgiksnlrdliy
rgrktawvmavyeddagelhrwkrtitangtseyrindrvvnaqqynealekenilikar
nflvfqgdveaiasqspqdltrlieqisgsleykeeyerleeevrqateeqayklqrrra
ans

  • Chain 'B':
    Sequence, based on SEQRES records:
    >6qpwB (B:)
maskaivqmakilrkelseekeviftdvlksqantepenitkreasrgffdilslategc
iglsqteafgnikidakpalferfi

    Sequence, based on observed residues (ATOM records):
    >6qpwB (B:)
kaivqmakilrkelseekeviftdvlksqantepenitkreasrgffdilslategcigl
sqteafgnikidakpalferf

  • Chain 'C':
    Sequence, based on SEQRES records:
    >6qpwC (C:)
mayikrviikgfktyrnetiidnfsphqnviigsngsgksnffaairfvlsddysnlkre
erqglihqgsggsvmsasveivfhdpdhsmilpsgvlsrgddevtirrtvglkkddyqln
drnvtkgdivrmletagfsmnnpynivpqgkivaltnakdkerlqlledvvgaksfevkl
kaslkkmeeteqkkiqinkemgelnsklsemeqerkelekynelernrkiyqftlydrel
nevinqmerldgdynntvyssesskhptslvprgsditsdqllqrlndmnteisglknvn
krafenfkkfnerrkdlaeraseldeskdsiqdlivklkqqkvnavdstfqkvsenfeav
ferlvprgtakliihrkndnandhdesidvdmdaesnesqngkdseimytgvsisvsfns
kqneqlhveqlsggqktvcaialilaiqmvdpasfylfdeidacldkqyrtavatllkel
sknaqficttfrtdmlqvadkffrvkyeckistvievnreeaigfirgsnkfaev

    Sequence, based on observed residues (ATOM records):
    >6qpwC (C:)
yikrviikgfktyrnetiidnfsphqnviigsngsgksnffaairfvlsddysnlkreer
qglihqgsggsvmsasveivfhdpdhsmilpsgvlsrgddevtirrtvglkkddyqlndr
nvtkgdivrmletagfsmnnpynivpqgkivaltnakdkerlqlledvvgaksfevklka
slkkmeeteqkkiqinkemgelndlaeraseldeskdsiqdlivklkqqkvnavdstfqk
vsenfeavferlvprgtakliihisvsfnskqneqlhveqlsggqktvcaialilaiqmv
dpasfylfdeidacldkqyrtavatllkelsknaqficttfrtdmlqvadkffrvkyeck
istvievnreeaigfir

  • Chain 'E':
    Sequence, based on SEQRES records:
    >6qpwE (E:)
mvtenpqrltvlrlatnkgplaqiwlasnmsniprgsviqthiaesakeiakasgsddes
gdneyitlrtsgellqgivrvyskqatflltdikdtltkismlfktsqkmtstvnrlntv
trvhqlmledavterevlvtpgleflddttipvglmaqenpnlramdrldhvrkqleqte
qefeaskaklrqaresfqavkqkrlelfnkafthiqeqithvykeltrseayplggqayl
dieedtdtpflsgvkyhamppckrfrdmehlsggektmaalallfaihsyqpspffvlde
vdcaldnanvekikkyirehagpgmqfivislkpalfqasesligvyrdqeantsrtltl
dlrkyrhhhhhh

    Sequence, based on observed residues (ATOM records):
    >6qpwE (E:)
hvrkqleqteqefeaskaklrqaresfqavkqkrlelfnkafthiqeqithvykeltrse
ayplggqayldieedtdtpflsgvkyhamppckrfrdmehlsggektmaalallfaihsy
qpspffvldevdcaldnanvekikkyirehagpgmqfivislkpalfqasesligvyrdq
eantsrtltldlrkyrhh