PDB entry 6qns

View 6qns on RCSB PDB site
Description: crystal structure of the binding domain of botulinum neurotoxin type b mutant i1248w/v1249w in complex with human synaptotagmin 1 and gd1a receptors
Deposited on 2019-02-12, released 2020-02-26
The last revision was dated 2020-07-29, with a file datestamp of 2020-06-29.
Experiment type: XRAY
Resolution: 2.4 Å
R-factor: N/A
AEROSPACI score: 0.31 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: botulinum neurotoxin type b
    Species: Clostridium botulinum [TaxId:1491]
    Gene: botB
    Database cross-references and differences (RAF-indexed):
    • Uniprot P10844 (Start-441)
      • engineered mutation (398-399)
  • Chain 'S':
    Compound: Synaptotagmin-1
    Species: HOMO SAPIENS, synthetic [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
  • Heterogens: BGC, GAL, NGA, SIA, HOH

PDB Chain Sequences:
This PDB entry is not classified in SCOPe 2.08, so the chain sequences below are not included in the ASTRAL sequence sets.

  • Chain 'A':
    Sequence, based on SEQRES records:
    >6qnsA (A:)
gshmasmnseilnniilnlrykdnnlidlsgygakvevydgvelndknqfkltssanski
rvtqnqniifnsvfldfsvsfwiripkykndgiqnyihneytiincmknnsgwkisirgn
riiwtlidingktksvffeynirediseyinrwffvtitnnlnnakiyingklesntdik
direviangeiifkldgdidrtqfiwmkyfsifntelsqsnieerykiqsyseylkdfwg
nplmynkeyymfnagnknsyiklkkdspvgeiltrskynqnskyinyrdlyigekfiirr
ksnsqsinddivrkedyiyldffnlnqewrvytykyfkkeeeklflapisdsdefyntiq
ikeydeqptyscqllfkkdeestdeigligihrfyesgwwfeeykdyfciskwylkevkr
kpynlklgcnwqfipkdegwte

    Sequence, based on observed residues (ATOM records):
    >6qnsA (A:)
nniilnlrykdnnlidlsgygakvevydgvelndknqfkltssanskirvtqnqniifns
vfldfsvsfwiripkykndgiqnyihneytiincmknnsgwkisirgnriiwtlidingk
tksvffeynirediseyinrwffvtitnnlnnakiyingklesntdikdireviangeii
fkldgdidrtqfiwmkyfsifntelsqsnieerykiqsyseylkdfwgnplmynkeyymf
nagnknsyiklkkdspvgeiltrskynqnskyinyrdlyigekfiirrksnsqsinddiv
rkedyiyldffnlnqewrvytykyfkkeeeklflapisdsdefyntiqikeydeqptysc
qllfkkdeestdeigligihrfyesgwwfeeykdyfciskwylkevkrkpynlklgcnwq
fipkdegwte

  • Chain 'S':
    Sequence, based on SEQRES records:
    >6qnsS (S:)
gegkedafsklkekfmnelhk

    Sequence, based on observed residues (ATOM records):
    >6qnsS (S:)
edafsklkekfmnelh