PDB entry 6qho

View 6qho on RCSB PDB site
Description: Dual specificity mitogen-activated protein kinase kinase 7 in complex with pyrazolopyrimidine 1a
Class: transferase
Keywords: Protein Kinase, Kinase, MKK7, TRANSFERASE
Deposited on 2019-01-17, released 2019-05-22
The last revision prior to the SCOPe 2.08 freeze date was dated 2019-06-26, with a file datestamp of 2019-06-21.
Experiment type: XRAY
Resolution: 2.7 Å
R-factor: N/A
AEROSPACI score: 0.17 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Dual specificity mitogen-activated protein kinase kinase 7
    Species: Homo sapiens [TaxId:9606]
    Gene: MAP2K7, JNKK2, MEK7, MKK7, PRKMK7, SKK4
    Database cross-references and differences (RAF-indexed):
    • Uniprot O14733 (20-End)
      • expression tag (11-19)
    Domains in SCOPe 2.08: d6qhoa1, d6qhoa2
  • Heterogens: J3H, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >6qhoA (A:)
mghhhhhhsakqtgyltiggqryqaeindlenlgemgsgtcgqvwkmrfrktghviavkq
mrrsgnkeenkrilmdldvvlkshdcpyivqcfgtfitntdvfiamelmgtcaeklkkrm
qgpiperilgkmtvaivkalyylkekhgvihrdvkpsnilldergqiklcdfgisgrlvd
skaktrsagcaaymaperidppdptkpdydiradvwslgislvelatgqfpykncktdfe
vltkvlqeeppllpghmgfsgdfqsfvkdcltkdhrkrpkynkllehsfikryetlevdv
aswfkdvmaktesprtsg

    Sequence, based on observed residues (ATOM records): (download) 
    >6qhoA (A:)
qtgyltiggqryqaeindlenlgemgsgtcgqvwkmrfrktghviavkqmrrsgnkeenk
rilmdldvvlkshdcpyivqcfgtfitntdvfiamelmgtcaeklkkrmqgpiperilgk
mtvaivkalyylkekhgvihrdvkpsnilldergqiklcdfgisgrymaperidpradvw
slgislvelatgqfpykncktdfevltkvlqeeppllpghmgfsgdfqsfvkdcltkdhr
krpkynkllehsfikryetlevdvaswfkdvmakt