PDB entry 6qh4

View 6qh4 on RCSB PDB site
Description: Crystal structure of human Methylmalonyl-CoA epimerase (MCEE) p.Arg143Cys variant
Class: isomerase
Keywords: Methylmalonyl-CoA epimerase, mitochondrial, ISOMERASE
Deposited on 2019-01-15, released 2019-02-27
The last revision prior to the SCOPe 2.08 freeze date was dated 2019-11-20, with a file datestamp of 2019-11-15.
Experiment type: XRAY
Resolution: 1.92 Å
R-factor: N/A
AEROSPACI score: 0.33 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Methylmalonyl-CoA epimerase, mitochondrial
    Species: Homo sapiens [TaxId:9606]
    Gene: MCEE
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q96PE7 (23-154)
      • expression tag (21-22)
      • variant (82)
    Domains in SCOPe 2.08: d6qh4a1, d6qh4a2
  • Chain 'B':
    Compound: Methylmalonyl-CoA epimerase, mitochondrial
    Species: Homo sapiens [TaxId:9606]
    Gene: MCEE
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q96PE7 (23-154)
      • expression tag (22)
      • variant (82)
      • engineered mutation (121)
    Domains in SCOPe 2.08: d6qh4b1, d6qh4b2
  • Chain 'C':
    Compound: Methylmalonyl-CoA epimerase, mitochondrial
    Species: Homo sapiens [TaxId:9606]
    Gene: MCEE
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q96PE7 (23-154)
      • expression tag (15-22)
      • variant (82)
      • engineered mutation (121)
    Domains in SCOPe 2.08: d6qh4c1, d6qh4c2
  • Chain 'D':
    Compound: Methylmalonyl-CoA epimerase, mitochondrial
    Species: Homo sapiens [TaxId:9606]
    Gene: MCEE
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q96PE7 (23-154)
      • expression tag (21-22)
      • variant (82)
      • engineered mutation (121)
    Domains in SCOPe 2.08: d6qh4d1, d6qh4d2
  • Heterogens: CO, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >6qh4A (A:)
mhhhhhhssgvdlgtenlyfqsmlgrlnhvaiavpdlekaaafyknilgaqvseavplpe
hgvsvvfvnlgntkmellhplgldspiagflqknkaggmhhicievdninaavmdlkkkk
icslseevkigahgkpviflhpkdcggvlveleqa

    Sequence, based on observed residues (ATOM records): (download) 
    >6qh4A (A:)
smlgrlnhvaiavpdlekaaafyknilgaqvseavplpehgvsvvfvnlgntkmellhpl
gldspiagflqknkaggmhhicievdninaavmdlkkkkilsevkigahgkpviflhpkd
cggvlveleqa

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >6qh4B (B:)
mhhhhhhssgvdlgtenlyfqsmlgrlnhvaiavpdlekaaafyknilgaqvseavplpe
hgvsvvfvnlgntkmellhplgldspiagflqknkaggmhhicievdninaavmdlkkkk
icslseevkigahgkpviflhpkdcggvlveleqa

    Sequence, based on observed residues (ATOM records): (download) 
    >6qh4B (B:)
mlgrlnhvaiavpdlekaaafyknilgaqvseavplpehgvsvvfvnlgntkmellhplg
ldspiagflqknkaggmhhicievdninaavmdlkkkkicslevkigahgkpviflhpkd
cggvlveleqa

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >6qh4C (C:)
mhhhhhhssgvdlgtenlyfqsmlgrlnhvaiavpdlekaaafyknilgaqvseavplpe
hgvsvvfvnlgntkmellhplgldspiagflqknkaggmhhicievdninaavmdlkkkk
icslseevkigahgkpviflhpkdcggvlveleqa

    Sequence, based on observed residues (ATOM records): (download) 
    >6qh4C (C:)
enlyfqsmlgrlnhvaiavpdlekaaafyknilgaqvseavplpehgvsvvfvnlgntkm
ellhplgldspiagflqknkaggmhhicievdninaavmdlkkkkicslsvkigahgkpv
iflhpkdcggvlveleqa

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >6qh4D (D:)
mhhhhhhssgvdlgtenlyfqsmlgrlnhvaiavpdlekaaafyknilgaqvseavplpe
hgvsvvfvnlgntkmellhplgldspiagflqknkaggmhhicievdninaavmdlkkkk
icslseevkigahgkpviflhpkdcggvlveleqa

    Sequence, based on observed residues (ATOM records): (download) 
    >6qh4D (D:)
smlgrlnhvaiavpdlekaaafyknilgaqvseavplpehgvsvvfvnlgntkmellhpl
gldspiagflqknkaggmhhicievdninaavmdlkkkkicslseevkigahgkpviflh
pkdcggvlveleqa