PDB entry 6qgo

View 6qgo on RCSB PDB site
Description: Crystal structure of APT1 S119A mutant bound to palmitic acid.
Class: hydrolase
Keywords: acyl-protein thioesterase, palmitic acid, Depalmitoylation, HYDROLASE
Deposited on 2019-01-12, released 2020-02-05
The last revision prior to the SCOPe 2.08 freeze date was dated 2021-03-31, with a file datestamp of 2021-03-26.
Experiment type: XRAY
Resolution: 2.6 Å
R-factor: N/A
AEROSPACI score: 0.25 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'B':
    Compound: Acyl-protein thioesterase 1
    Species: Homo sapiens [TaxId:9606]
    Gene: LYPLA1, APT1, LPL1
    Database cross-references and differences (RAF-indexed):
    • Uniprot O75608
      • engineered mutation (121)
    Domains in SCOPe 2.08: d6qgob_
  • Chain 'C':
    Compound: Acyl-protein thioesterase 1
    Species: Homo sapiens [TaxId:9606]
    Gene: LYPLA1, APT1, LPL1
    Database cross-references and differences (RAF-indexed):
    • Uniprot O75608
      • engineered mutation (121)
    Domains in SCOPe 2.08: d6qgoc_
  • Heterogens: PLM, HOH

PDB Chain Sequences:

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >6qgoB (B:)
gsrmcgnnmstplpaivpaarkataaviflhglgdtghgwaeafagirsshikyicphap
vrpvtlnmnvampswfdiiglspdsqedesgikqaaenikalidqevkngipsnriilgg
faqggalslytalttqqklagvtalscwlplrasfpqgpigganrdisilqchgdcdplv
plmfgsltveklktlvnpanvtfktyegmmhsscqqemmdvkqfidkllppid

    Sequence, based on observed residues (ATOM records): (download) 
    >6qgoB (B:)
plpaivpaarkataaviflhglgdtghgwaeafagirsshikyicphapvrpvtlnmnva
mpswfdiiglspdsqedesgikqaaenikalidqevkngipsnriilggfaqggalslyt
alttqqklagvtalscwlplrasfpqgpigganrdisilqchgdcdplvplmfgsltvek
lktlvnpanvtfktyegmmhsscqqemmdvkqfidkllppi

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >6qgoC (C:)
gsrmcgnnmstplpaivpaarkataaviflhglgdtghgwaeafagirsshikyicphap
vrpvtlnmnvampswfdiiglspdsqedesgikqaaenikalidqevkngipsnriilgg
faqggalslytalttqqklagvtalscwlplrasfpqgpigganrdisilqchgdcdplv
plmfgsltveklktlvnpanvtfktyegmmhsscqqemmdvkqfidkllppid

    Sequence, based on observed residues (ATOM records): (download) 
    >6qgoC (C:)
stplpaivpaarkataaviflhglgdtghgwaeafagirsshikyicphapvrpvtlnmn
vampswfdiiglspdsqedesgikqaaenikalidqevkngipsnriilggfaqggalsl
ytalttqqklagvtalscwlplrasfpqgpigganrdisilqchgdcdplvplmfgsltv
eklktlvnpanvtfktyegmmhsscqqemmdvkqfidkllppi