PDB entry 6qgn

View 6qgn on RCSB PDB site
Description: Crystal structure of APT1 bound to 2-Bromopalmitate
Class: hydrolase
Keywords: acyl-protein thioesterase 2-bromopalmitate Depalmitoylation, HYDROLASE
Deposited on 2019-01-12, released 2020-02-05
The last revision prior to the SCOPe 2.08 freeze date was dated 2021-03-31, with a file datestamp of 2021-03-26.
Experiment type: XRAY
Resolution: 2.1 Å
R-factor: N/A
AEROSPACI score: 0.36 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Acyl-protein thioesterase 1
    Species: Homo sapiens [TaxId:9606]
    Gene: LYPLA1, APT1, LPL1
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d6qgna_
  • Chain 'B':
    Compound: Acyl-protein thioesterase 1
    Species: Homo sapiens [TaxId:9606]
    Gene: LYPLA1, APT1, LPL1
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d6qgnb_
  • Chain 'C':
    Compound: Acyl-protein thioesterase 1
    Species: Homo sapiens [TaxId:9606]
    Gene: LYPLA1, APT1, LPL1
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d6qgnc_
  • Chain 'D':
    Compound: Acyl-protein thioesterase 1
    Species: Homo sapiens [TaxId:9606]
    Gene: LYPLA1, APT1, LPL1
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d6qgnd_
  • Heterogens: J1W, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >6qgnA (A:)
gsrmsgnnmstplpaivpaarkataaviflhglgdtghgwaeafagirsshikyicphap
vrpvtlnmnvampswfdiiglspdsqedesgikqaaenikalidqevkngipsnriilgg
fsqggalslytalttqqklagvtalscwlplrasfpqgpigganrdisilqchgdcdplv
plmfgsltveklktlvnpanvtfktyegmmhsscqqemmdvkqfidkllppid

    Sequence, based on observed residues (ATOM records): (download) 
    >6qgnA (A:)
tplpaivpaarkataaviflhglgdtghgwaeafagirsshikyicphapvrpvtlnmnv
ampswfdiiglspdsqedesgikqaaenikalidqevkngipsnriilggfsqggalsly
talttqqklagvtalscwlplrasfpqgpigganrdisilqchgdcdplvplmfgsltve
klktlvnpanvtfktyegmmhsscqqemmdvkqfidkllppid

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >6qgnB (B:)
gsrmsgnnmstplpaivpaarkataaviflhglgdtghgwaeafagirsshikyicphap
vrpvtlnmnvampswfdiiglspdsqedesgikqaaenikalidqevkngipsnriilgg
fsqggalslytalttqqklagvtalscwlplrasfpqgpigganrdisilqchgdcdplv
plmfgsltveklktlvnpanvtfktyegmmhsscqqemmdvkqfidkllppid

    Sequence, based on observed residues (ATOM records): (download) 
    >6qgnB (B:)
tplpaivpaarkataaviflhglgdtghgwaeafagirsshikyicphapvrpvtlnmnv
ampswfdiiglspdsqedesgikqaaenikalidqevkngipsnriilggfsqggalsly
talttqqklagvtalscwlplrasfpqgpigganrdisilqchgdcdplvplmfgsltve
klktlvnpanvtfktyegmmhsscqqemmdvkqfidkllppid

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >6qgnC (C:)
gsrmsgnnmstplpaivpaarkataaviflhglgdtghgwaeafagirsshikyicphap
vrpvtlnmnvampswfdiiglspdsqedesgikqaaenikalidqevkngipsnriilgg
fsqggalslytalttqqklagvtalscwlplrasfpqgpigganrdisilqchgdcdplv
plmfgsltveklktlvnpanvtfktyegmmhsscqqemmdvkqfidkllppid

    Sequence, based on observed residues (ATOM records): (download) 
    >6qgnC (C:)
tplpaivpaarkataaviflhglgdtghgwaeafagirsshikyicphapvrpvtlnmnv
ampswfdiiglspdsqedesgikqaaenikalidqevkngipsnriilggfsqggalsly
talttqqklagvtalscwlplrasfpqgpigganrdisilqchgdcdplvplmfgsltve
klktlvnpanvtfktyegmmhsscqqemmdvkqfidkllppid

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >6qgnD (D:)
gsrmsgnnmstplpaivpaarkataaviflhglgdtghgwaeafagirsshikyicphap
vrpvtlnmnvampswfdiiglspdsqedesgikqaaenikalidqevkngipsnriilgg
fsqggalslytalttqqklagvtalscwlplrasfpqgpigganrdisilqchgdcdplv
plmfgsltveklktlvnpanvtfktyegmmhsscqqemmdvkqfidkllppid

    Sequence, based on observed residues (ATOM records): (download) 
    >6qgnD (D:)
tplpaivpaarkataaviflhglgdtghgwaeafagirsshikyicphapvrpvtlnmnv
ampswfdiiglspdsqedesgikqaaenikalidqevkngipsnriilggfsqggalsly
talttqqklagvtalscwlplrasfpqgpigganrdisilqchgdcdplvplmfgsltve
klktlvnpanvtfktyegmmhsscqqemmdvkqfidkllppid