PDB entry 6qgg

View 6qgg on RCSB PDB site
Description: Structure of human Bcl-2 in complex with analogue of ABT-737
Class: apoptosis
Keywords: apoptosis, bcl2, abt-737
Deposited on 2019-01-11, released 2019-06-12
The last revision prior to the SCOPe 2.08 freeze date was dated 2019-09-11, with a file datestamp of 2019-09-06.
Experiment type: XRAY
Resolution: 1.5 Å
R-factor: N/A
AEROSPACI score: 0.49 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Apoptosis regulator Bcl-2,Bcl-2-like protein 1,Apoptosis regulator Bcl-2,Bcl-2-like protein 1
    Species: Homo sapiens [TaxId:9606]
    Gene: BCL2L1, BCL2L, BCLX
    Database cross-references and differences (RAF-indexed):
    • Uniprot P10415 (3-End)
      • expression tag (1-2)
      • engineered mutation (13)
    • Uniprot Q07817 (Start-42)
    • Uniprot P10415 (43-154)
      • engineered mutation (46)
      • engineered mutation (57)
      • engineered mutation (75)
      • engineered mutation (78-80)
      • engineered mutation (119)
      • engineered mutation (126)
      • engineered mutation (129-130)
      • engineered mutation (134)
    • Uniprot Q07817
    Domains in SCOPe 2.08: d6qgga1, d6qgga2
  • Heterogens: J1H, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >6qggA (A:)
msqdnreivmkyisyklsqrgyewdagdveenrteapegtesevvhqtlrqagddfslry
rrdfaemssqlhltpgtayasfatvveelfrdgvnwgrivaffefggvmcvesvnremsv
lvdniaawmatylndhlhtwiqdnggwdafvelygnnaaaesrkgqerflehhhhhh

    Sequence, based on observed residues (ATOM records): (download) 
    >6qggA (A:)
sqdnreivmkyisyklsqrgyewdtesevvhqtlrqagddfslryrrdfaemssqlhltp
gtayasfatvveelfrdgvnwgrivaffefggvmcvesvnremsvlvdniaawmatylnd
hlhtwiqdnggwdafvelyg