PDB entry 6qfq

View 6qfq on RCSB PDB site
Description: Structure of human Mcl-1 in complex with indole acid inhibitor
Class: apoptosis
Keywords: APOPTOSIS, MCL1, BCL2, small molecule inhibitor
Deposited on 2019-01-10, released 2019-06-12
The last revision prior to the SCOPe 2.07 freeze date was dated 2019-06-12, with a file datestamp of 2019-06-07.
Experiment type: XRAY
Resolution: 1.6 Å
R-factor: N/A
AEROSPACI score: 0.44 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Induced myeloid leukemia cell differentiation protein Mcl-1
    Species: Homo sapiens [TaxId:9606]
    Gene: MCL1, BCL2L3
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d6qfqa_
  • Heterogens: J3E, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >6qfqA (A:)
mhhhhhhlvprgsedelyrqsleiisrylreqatgakdtkpmgrsgatsrkaletlrrvg
dgvqrnhetafqgmlrkldikneddvkslsrvmihvfsdgvtnwgrivtlisfgafvakh
lktinqescieplaesitdvlvrtkrdwlvkqrgwdgfveffhvedlegg

    Sequence, based on observed residues (ATOM records): (download) 
    >6qfqA (A:)
delyrqsleiisrylreqatgakdtkpmgrsgatsrkaletlrrvgdgvqrnhetafqgm
lrkldikneddvkslsrvmihvfsdgvtnwgrivtlisfgafvakhlktinqesciepla
esitdvlvrtkrdwlvkqrgwdgfveffhv