PDB entry 6qeg

View 6qeg on RCSB PDB site
Description: crystal structure of human methionine aminopeptidase-2 in complex with an inhibitor 2-oxo-1-phenyl-pyrrolidine-3-carboxylic acid (2- thiophen-2-yl-ethyl)-amide
Deposited on 2019-01-07, released 2019-05-01
The last revision was dated 2019-06-05, with a file datestamp of 2019-05-30.
Experiment type: XRAY
Resolution: 2.08 Å
R-factor: N/A
AEROSPACI score: 0.29 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Methionine aminopeptidase 2
    Species: Homo sapiens [TaxId:9606]
    Gene: METAP2, MNPEP, P67EIF2
    Database cross-references and differences (RAF-indexed):
  • Heterogens: GOL, K4K, MN, HOH

PDB Chain Sequences:
This PDB entry is not classified in SCOPe 2.08, so the chain sequences below are not included in the ASTRAL sequence sets.

  • Chain 'A':
    Sequence, based on SEQRES records:
    >6qegA (A:)
    mgpkvqtdppsvpicdlypngvfpkgqeceypptqdgrtaawrttseekkaldqaseeiw
    ndfreaaeahrqvrkyvmswikpgmtmieicekledcsrklikenglnaglafptgcsln
    ncaahytpnagdttvlqyddickidfgthisgriidcaftvtfnpkydtllkavkdatnt
    gikcagidvrlcdvgeaiqevmesyeveidgktyqvkpirnlnghsigqyrihagktvpi
    vkggeatrmeegevyaietfgstgkgvvhddmecshymknfdvghvpirlprtkhllnvi
    nenfgtlafcrrwldrlgeskylmalknlcdlgivdpypplcdikgsytaqfehtillrp
    tckevvsrgddyhhhhhh
    

    Sequence, based on observed residues (ATOM records):
    >6qegA (A:)
    vqtdppsvpicdlypngvfpkgqeceypptqdgrtaawrttseekkaldqaseeiwndfr
    eaaeahrqvrkyvmswikpgmtmieicekledcsrklikenglnaglafptgcslnncaa
    hytpnagdttvlqyddickidfgthisgriidcaftvtfnpkydtllkavkdatntgikc
    agidvrlcdvgeaiqevmesyeveidgktyqvkpirnlnghsigqyrihagktvpivkgg
    eatrmeegevyaietfgstgkgvvhddmecshymknfdvghvpirlprtkhllnvinenf
    gtlafcrrwldrlgeskylmalknlcdlgivdpypplcdikgsytaqfehtillrptcke
    vvsr