PDB entry 6qce

View 6qce on RCSB PDB site
Description: human sirt6 in complex with adp-ribose and the activator isoquercetin
Deposited on 2018-12-27, released 2019-12-25
The last revision was dated 2019-12-25, with a file datestamp of 2019-12-20.
Experiment type: XRAY
Resolution: 1.9 Å
R-factor: N/A
AEROSPACI score: 0.34 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: nad-dependent protein deacetylase sirtuin-6
    Species: Homo sapiens [TaxId:9606]
    Gene: SIRT6, SIR2L6
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q8N6T7 (6-End)
      • expression tag (3-5)
  • Chain 'B':
    Compound: nad-dependent protein deacetylase sirtuin-6
    Species: Homo sapiens [TaxId:9606]
    Gene: SIRT6, SIR2L6
    Database cross-references and differences (RAF-indexed):
  • Heterogens: AR6, ZN, SO4, HW2, EDO, HOH

PDB Chain Sequences:
This PDB entry is not classified in SCOPe 2.08, so the chain sequences below are not included in the ASTRAL sequence sets.

  • Chain 'A':
    Sequence, based on SEQRES records:
    >6qceA (A:)
gidpftadkgkcglpeifdppeelerkvwelarlvwqsssvvfhtgagistasgipdfrg
phgvwtmeerglapkfdttfesarptqthmalvqlervgllrflvsqnvdglhvrsgfpr
dklaelhgnmfveecakcktqyvrdtvvgtmglkatgrlctvakarglracrgelrdtil
dwedslpdrdlaladeasrnadlsitlgtslqirpsgnlplatkrrggrlvivnlqptkh
drhadlrihgyvdevmtrlmkhlgleipawdgprvleralpplprpptpklepkeesptr
in

    Sequence, based on observed residues (ATOM records):
    >6qceA (A:)
pftadkgkcglpeifdppeelerkvwelarlvwqsssvvfhtgagistasgipdfrgphg
vwtmeerglapkfdttfesarptqthmalvqlervgllrflvsqnvdglhvrsgfprdkl
aelhgnmfveecakcktqyvrdtvvgtmglkatgrlctvacrgelrdtildwedslpdrd
laladeasrnadlsitlgtslqirpsgnlplatkrrggrlvivnlqptkhdrhadlrihg
yvdevmtrlmkhlgleipawdgprvleralpplprpptpkle

  • Chain 'B':
    Sequence, based on SEQRES records:
    >6qceB (B:)
gidpftadkgkcglpeifdppeelerkvwelarlvwqsssvvfhtgagistasgipdfrg
phgvwtmeerglapkfdttfesarptqthmalvqlervgllrflvsqnvdglhvrsgfpr
dklaelhgnmfveecakcktqyvrdtvvgtmglkatgrlctvakarglracrgelrdtil
dwedslpdrdlaladeasrnadlsitlgtslqirpsgnlplatkrrggrlvivnlqptkh
drhadlrihgyvdevmtrlmkhlgleipawdgprvleralpplprpptpklepkeesptr
in

    Sequence, based on observed residues (ATOM records):
    >6qceB (B:)
kgkcglpeifdppeelerkvwelarlvwqsssvvfhtgagistasgipdfrgphgvwtme
erglapkfdttfesarptqthmalvqlervgllrflvsqnvdglhvrsgfprdklaelhg
nmfveecakcktqyvrdtvvgtmglkatgrlctvacrgelrdtildwedslpdrdlalad
easrnadlsitlgtslqirpsgnlplatkrrggrlvivnlqptkhdrhadlrihgyvdev
mtrlmkhlgleipawdgprvleralpplprpptpkle