PDB entry 6qbc

View 6qbc on RCSB PDB site
Description: structure of anti-Mcl1 Fab
Class: apoptosis
Keywords: Mcl1, Fab, AZD5991, APOPTOSIS
Deposited on 2018-12-20, released 2019-11-06
The last revision prior to the SCOPe 2.08 freeze date was dated 2019-11-13, with a file datestamp of 2019-11-08.
Experiment type: XRAY
Resolution: 1.56 Å
R-factor: N/A
AEROSPACI score: 0.45 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'H':
    Compound: Anti-Mcl1 Fab Heavy Chain
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 6QBC (0-End)
    Domains in SCOPe 2.08: d6qbch_
  • Chain 'L':
    Compound: Anti-Mcl1 Fab Light Chain
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 6QBC
    Domains in SCOPe 2.08: d6qbcl1, d6qbcl2
  • Heterogens: HOH

PDB Chain Sequences:

  • Chain 'H':
    Sequence, based on SEQRES records: (download) 
    >6qbcH (H:)
qvtlkesggglvkpggslrlscaasgftfssysmnwvrqapgkglewvssisssssyiyy
adsvkgrftisrdnaknslylqmnslraedtavyycarqvgatwafdiwgqgtlvtvsaa
kttppsvyplapgsaaqtnsmvtlgclvkgyfpepvtvtwnsgslssgvhtfpavlqsdl
ytlsssvtvpssprpsetvtcnvahpasstkvdkkivprdcaaaenlyfq

    Sequence, based on observed residues (ATOM records): (download) 
    >6qbcH (H:)
qvtlkesggglvkpggslrlscaasgftfssysmnwvrqapgkglewvssisssssyiyy
adsvkgrftisrdnaknslylqmnslraedtavyycarqvgatwafdiwgqgtlvtvsaa
kttppsvyplapnsmvtlgclvkgyfpepvtvtwnsgslssgvhtfpavlqsdlytlsss
vtvtvtcnvahpasstkvdkkivp

  • Chain 'L':
    Sequence, based on SEQRES records: (download) 
    >6qbcL (L:)
qsvltqppsasgtpgqrvtiscsgsssnigsntvnwyqqlpgtapklliysnnqrpsgvp
drfsgsksgtsaslaisglqsedeadyycaawddslnawvfgggtkltvlgesegqpkss
psvtlfppsseeletnkatlvctitdfypgvvtvdwkvdgtpvtqgmettqpskqsnnky
massyltltarawerhssyscqvtheghtvekslsradcs

    Sequence, based on observed residues (ATOM records): (download) 
    >6qbcL (L:)
vltqppsasgtpgqrvtiscsgsssnigsntvnwyqqlpgtapklliysnnqrpsgvpdr
fsgsksgtsaslaisglqsedeadyycaawddslnawvfgggtkltvlgqpksspsvtlf
ppsseeletnkatlvctitdfypgvvtvdwkvdgtpvtqgmettqpskqsnnkymassyl
tltarawerhssyscqvtheghtvekslsr