PDB entry 6qat

View 6qat on RCSB PDB site
Description: Crystal structure of ULK2 in complexed with hesperadin
Class: transferase
Keywords: ULK2, autophagy, kinase, inhibitor complex, Structural Genomics, Structural Genomics Consortium, SGC, TRANSFERASE
Deposited on 2018-12-19, released 2019-02-27
The last revision prior to the SCOPe 2.08 freeze date was dated 2019-03-20, with a file datestamp of 2019-03-15.
Experiment type: XRAY
Resolution: 2.77 Å
R-factor: N/A
AEROSPACI score: 0.17 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Serine/threonine-protein kinase ULK2
    Species: Homo sapiens [TaxId:9606]
    Gene: ULK2, KIAA0623
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d6qata_
  • Chain 'B':
    Compound: Serine/threonine-protein kinase ULK2
    Species: Homo sapiens [TaxId:9606]
    Gene: ULK2, KIAA0623
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q8IYT8 (4-End)
      • expression tag (0-3)
    Domains in SCOPe 2.08: d6qatb1, d6qatb2
  • Chain 'C':
    Compound: Serine/threonine-protein kinase ULK2
    Species: Homo sapiens [TaxId:9606]
    Gene: ULK2, KIAA0623
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q8IYT8 (4-End)
      • expression tag (3)
    Domains in SCOPe 2.08: d6qatc1, d6qatc2
  • Chain 'D':
    Compound: Serine/threonine-protein kinase ULK2
    Species: Homo sapiens [TaxId:9606]
    Gene: ULK2, KIAA0623
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d6qatd_
  • Heterogens: FE7, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >6qatA (A:)
gggsmevvgdfeyskrdlvghgafavvfrgrhrqktdwevaiksinkknlsksqillgke
ikilkelqhenivalydvqelpnsvflvmeycnggdladylqakgtlsedtirvflhqia
aamrilhskgiihrdlkpqnillsyanrrkssvsgirikiadfgfarylhsnmmaadlcg
spmymapevimsqhydakadlwsigtviyqclvgkppfqanspqdlrmfyeknrslmpsi
pretspylanlllgllqrnqkdrmdfeaffshpfleqgpv

    Sequence, based on observed residues (ATOM records): (download) 
    >6qatA (A:)
mevvgdfeyskrdlvghgafavvfrgrhrqktdwevaiksinkknlsksqillgkeikil
kelqhenivalydvqelpnsvflvmeycnggdladylqakgtlsedtirvflhqiaaamr
ilhskgiihrdlkpqnillsyanvsgirikiadfgfarylhspmymapevimsqhydaka
dlwsigtviyqclvgkppfqanspqdlrmfyeknrslmpsipretspylanlllgllqrn
qkdrmdfeaffshpfleqg

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >6qatB (B:)
gggsmevvgdfeyskrdlvghgafavvfrgrhrqktdwevaiksinkknlsksqillgke
ikilkelqhenivalydvqelpnsvflvmeycnggdladylqakgtlsedtirvflhqia
aamrilhskgiihrdlkpqnillsyanrrkssvsgirikiadfgfarylhsnmmaadlcg
spmymapevimsqhydakadlwsigtviyqclvgkppfqanspqdlrmfyeknrslmpsi
pretspylanlllgllqrnqkdrmdfeaffshpfleqgpv

    Sequence, based on observed residues (ATOM records): (download) 
    >6qatB (B:)
gggsmevvgdfeyskrdlvghgafavvfrgrhrqktdwevaiksinkknlsksqillgke
ikilkelqhenivalydvqelpnsvflvmeycnggdladylqakgtlsedtirvflhqia
aamrilhskgiihrdlkpqnillsyanvsgirikiadfgfarylhspmymapevimsqhy
dakadlwsigtviyqclvgkppfmpsipretspylanlllgllqrnqkdrmdfeaffshp
fleqg

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >6qatC (C:)
gggsmevvgdfeyskrdlvghgafavvfrgrhrqktdwevaiksinkknlsksqillgke
ikilkelqhenivalydvqelpnsvflvmeycnggdladylqakgtlsedtirvflhqia
aamrilhskgiihrdlkpqnillsyanrrkssvsgirikiadfgfarylhsnmmaadlcg
spmymapevimsqhydakadlwsigtviyqclvgkppfqanspqdlrmfyeknrslmpsi
pretspylanlllgllqrnqkdrmdfeaffshpfleqgpv

    Sequence, based on observed residues (ATOM records): (download) 
    >6qatC (C:)
smevvgdfeyskrdlvghgafavvfrgrhrqktdwevaiksinkknlsksqillgkeiki
lkelqhenivalydvqelpnsvflvmeycnggdladylqakgtlsedtirvflhqiaaam
rilhskgiihrdlkpqnillsyasgirikiadfgfarylhspmymapevimsqhydakad
lwsigtviyqclvgkppfqanspqdlrmfyeknrslmpsipretspylanlllgllqrnq
kdrmdfeaffshpfleq

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >6qatD (D:)
gggsmevvgdfeyskrdlvghgafavvfrgrhrqktdwevaiksinkknlsksqillgke
ikilkelqhenivalydvqelpnsvflvmeycnggdladylqakgtlsedtirvflhqia
aamrilhskgiihrdlkpqnillsyanrrkssvsgirikiadfgfarylhsnmmaadlcg
spmymapevimsqhydakadlwsigtviyqclvgkppfqanspqdlrmfyeknrslmpsi
pretspylanlllgllqrnqkdrmdfeaffshpfleqgpv

    Sequence, based on observed residues (ATOM records): (download) 
    >6qatD (D:)
mevvgdfeyskrdlvghgafavvfrgrhrqktdwevaiksinkknlsksqillgkeikil
kelqhenivalydvqelpnsvflvmeycnggdladylqakgtlsedtirvflhqiaaamr
ilhskgiihrdlkpqnillsyavsgirikiadfgfarylpmymapevimsqhydakadlw
sigtviyqclvgkppfqanspqdlrmfyeknrslmpsipretspylanlllgllqrnqkd
rmdfeaffshpf