SCOPe 2.08: Structural Classification of Proteins

PDB entry 6qap

View 6qap on RCSB PDB site
Description: Structure of the human aldehyde dehydrogenase 9A1 in C2 space group
Class: oxidoreductase
Keywords: Oxidoreductase
Deposited on 2018-12-19, released 2019-04-10
The last revision prior to the SCOPe 2.08 freeze date was dated 2019-05-08, with a file datestamp of 2019-05-03.
Experiment type: XRAY
Resolution: 2.3 Å
R-factor: N/A
AEROSPACI score: 0.24 (click here for full SPACI score report)

Chains and heterogens:

Chain 'A':
Compound: 4-trimethylaminobutyraldehyde dehydrogenase
Species: Homo sapiens [TaxId:9606]
Gene: ALDH9A1, ALDH4, ALDH7, ALDH9
Database cross-references and differences (RAF-indexed):
- Uniprot P49189 (14-507)
  - expression tag (13)
Domains in SCOPe 2.08: d6qapa1, d6qapa2
Chain 'B':
Compound: 4-trimethylaminobutyraldehyde dehydrogenase
Species: Homo sapiens [TaxId:9606]
Gene: ALDH9A1, ALDH4, ALDH7, ALDH9
Database cross-references and differences (RAF-indexed):
- Uniprot P49189 (14-507)
  - expression tag (13)
Domains in SCOPe 2.08: d6qapb1, d6qapb2
Chain 'C':
Compound: 4-trimethylaminobutyraldehyde dehydrogenase
Species: Homo sapiens [TaxId:9606]
Gene: ALDH9A1, ALDH4, ALDH7, ALDH9
Database cross-references and differences (RAF-indexed):
- Uniprot P49189 (14-507)
  - expression tag (13)
Domains in SCOPe 2.08: d6qapc1, d6qapc2
Chain 'D':
Compound: 4-trimethylaminobutyraldehyde dehydrogenase
Species: Homo sapiens [TaxId:9606]
Gene: ALDH9A1, ALDH4, ALDH7, ALDH9
Database cross-references and differences (RAF-indexed):
- Uniprot P49189 (14-507)
  - expression tag (13)
Domains in SCOPe 2.08: d6qapd1, d6qapd2
Heterogens: EDO, PEG, NA, HOH

PDB Chain Sequences:

Chain 'A':
Sequence, based on SEQRES records: (download)

>6qapA (A:)
mgsshhhhhhsqdpmstgtfvvsqplnyrggarvepadasgtekafepatgrviatftcs
gekevnlavqnakaafkiwsqksgmercrilleaariireredeiatmecinngksifea
rldidiswqcleyyaglaasmagehiqlpggsfgytrreplgvcvgigawnypfqiaswk
sapalacgnamvfkpspftpvsalllaeiyseagvppglfnvvqggaatgqflcqhpdva
kvsftgsvptgmkimemsakgikpvtlelggkspliifsdcdmnnavkgalmanfltqgq
vccngtrvfvqkeildkfteevvkqtqrikigdplledtrmgplinrphlervlgfvkva
keqgakvlcggdiyvpedpklkdgyymrpcvltncrddmtcvkeeifgpvmsilsfdtea
evlerandttfglaagvftrdiqrahrvvaelqagtcfinnynvspvelpfggykksgfg
rengrvtieyysqlktvcvemgdvesaf

Sequence, based on observed residues (ATOM records): (download)

>6qapA (A:)
pmstgtfvvsqplnyrggarvepadasgtekafepatgrviatftcsgekevnlavqnak
aafkiwsqksgmercrilleaariireredeiatmecinngksifearldidiswqcley
yaglaasmagehiqlpggsfgytrreplgvcvgigawnypfqiaswksapalacgnamvf
kpspftpvsalllaeiyseagvppglfnvvqggaatgqflcqhpdvakvsftgkspliif
sdcdmnnavkgalmanfltqgqvccngtrvfvqkeildkfteevvkqtqrikigdplled
trmgplinrphlervlgfvkvakeqgakvlcggdiyvpedpklkdgyymrpcvltncrdd
mtcvkeeifgpvmsilsfdteaevlerandttfglaagvftrdiqrahrvvaelqagtcf
innynvspvelpfggykksgfgrengrvtieyysqlktvcvemgdvesaf

Chain 'B':
Sequence, based on SEQRES records: (download)

>6qapB (B:)
mgsshhhhhhsqdpmstgtfvvsqplnyrggarvepadasgtekafepatgrviatftcs
gekevnlavqnakaafkiwsqksgmercrilleaariireredeiatmecinngksifea
rldidiswqcleyyaglaasmagehiqlpggsfgytrreplgvcvgigawnypfqiaswk
sapalacgnamvfkpspftpvsalllaeiyseagvppglfnvvqggaatgqflcqhpdva
kvsftgsvptgmkimemsakgikpvtlelggkspliifsdcdmnnavkgalmanfltqgq
vccngtrvfvqkeildkfteevvkqtqrikigdplledtrmgplinrphlervlgfvkva
keqgakvlcggdiyvpedpklkdgyymrpcvltncrddmtcvkeeifgpvmsilsfdtea
evlerandttfglaagvftrdiqrahrvvaelqagtcfinnynvspvelpfggykksgfg
rengrvtieyysqlktvcvemgdvesaf

Sequence, based on observed residues (ATOM records): (download)

>6qapB (B:)
pmstgtfvvsqplnyrggarvepadasgtekafepatgrviatftcsgekevnlavqnak
aafkiwsqksgmercrilleaariireredeiatmecinngksifearldidiswqcley
yaglaasmagehiqlpggsfgytrreplgvcvgigawnypfqiaswksapalacgnamvf
kpspftpvsalllaeiyseagvppglfnvvqggaatgqflcqhpdvakvsftgkspliif
sdcdmnnavkgalmanfltqgqvccngtrvfvqkeildkfteevvkqtqrikigdplled
trmgplinrphlervlgfvkvakeqgakvlcggdiyvpedpklkdgyymrpcvltncrdd
mtcvkeeifgpvmsilsfdteaevlerandttfglaagvftrdiqrahrvvaelqagtcf
innynvspvelpfggykksgfgrengrvtieyysqlktvcvemgdvesaf

Chain 'C':
Sequence, based on SEQRES records: (download)

>6qapC (C:)
mgsshhhhhhsqdpmstgtfvvsqplnyrggarvepadasgtekafepatgrviatftcs
gekevnlavqnakaafkiwsqksgmercrilleaariireredeiatmecinngksifea
rldidiswqcleyyaglaasmagehiqlpggsfgytrreplgvcvgigawnypfqiaswk
sapalacgnamvfkpspftpvsalllaeiyseagvppglfnvvqggaatgqflcqhpdva
kvsftgsvptgmkimemsakgikpvtlelggkspliifsdcdmnnavkgalmanfltqgq
vccngtrvfvqkeildkfteevvkqtqrikigdplledtrmgplinrphlervlgfvkva
keqgakvlcggdiyvpedpklkdgyymrpcvltncrddmtcvkeeifgpvmsilsfdtea
evlerandttfglaagvftrdiqrahrvvaelqagtcfinnynvspvelpfggykksgfg
rengrvtieyysqlktvcvemgdvesaf

Sequence, based on observed residues (ATOM records): (download)

>6qapC (C:)
pmstgtfvvsqplnyrggarvepadasgtekafepatgrviatftcsgekevnlavqnak
aafkiwsqksgmercrilleaariireredeiatmecinngksifearldidiswqcley
yaglaasmagehiqlpggsfgytrreplgvcvgigawnypfqiaswksapalacgnamvf
kpspftpvsalllaeiyseagvppglfnvvqggaatgqflcqhpdvakvsftggksplii
fsdcdmnnavkgalmanfltqgqvccngtrvfvqkeildkfteevvkqtqrikigdplle
dtrmgplinrphlervlgfvkvakeqgakvlcggdiyvpedpklkdgyymrpcvltncrd
dmtcvkeeifgpvmsilsfdteaevlerandttfglaagvftrdiqrahrvvaelqagtc
finnynvspvelpfggykksgfgrengrvtieyysqlktvcvemgdvesaf

Chain 'D':
Sequence, based on SEQRES records: (download)

>6qapD (D:)
mgsshhhhhhsqdpmstgtfvvsqplnyrggarvepadasgtekafepatgrviatftcs
gekevnlavqnakaafkiwsqksgmercrilleaariireredeiatmecinngksifea
rldidiswqcleyyaglaasmagehiqlpggsfgytrreplgvcvgigawnypfqiaswk
sapalacgnamvfkpspftpvsalllaeiyseagvppglfnvvqggaatgqflcqhpdva
kvsftgsvptgmkimemsakgikpvtlelggkspliifsdcdmnnavkgalmanfltqgq
vccngtrvfvqkeildkfteevvkqtqrikigdplledtrmgplinrphlervlgfvkva
keqgakvlcggdiyvpedpklkdgyymrpcvltncrddmtcvkeeifgpvmsilsfdtea
evlerandttfglaagvftrdiqrahrvvaelqagtcfinnynvspvelpfggykksgfg
rengrvtieyysqlktvcvemgdvesaf

Sequence, based on observed residues (ATOM records): (download)

>6qapD (D:)
pmstgtfvvsqplnyrggarvepadasgtekafepatgrviatftcsgekevnlavqnak
aafkiwsqksgmercrilleaariireredeiatmecinngksifearldidiswqcley
yaglaasmagehiqlpggsfgytrreplgvcvgigawnypfqiaswksapalacgnamvf
kpspftpvsalllaeiyseagvppglfnvvqggaatgqflcqhpdvakvsftggksplii
fsdcdmnnavkgalmanfltqgqvccngtrvfvqkeildkfteevvkqtqrikigdplle
dtrmgplinrphlervlgfvkvakeqgakvlcggdiyvpedpklkdgyymrpcvltncrd
dmtcvkeeifgpvmsilsfdteaevlerandttfglaagvftrdiqrahrvvaelqagtc
finnynvspvelpfggykksgfgrengrvtieyysqlktvcvemgdvesaf