PDB entry 6q9z

View 6q9z on RCSB PDB site
Description: crystal structure of the pathological g167r variant of calcium-free human gelsolin,
Deposited on 2018-12-18, released 2019-11-27
The last revision was dated 2020-02-05, with a file datestamp of 2020-01-31.
Experiment type: XRAY
Resolution: 3.8 Å
R-factor: N/A
AEROSPACI score: 0.06 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: gelsolin
    Species: Homo sapiens [TaxId:9606]
    Gene: GSN
    Database cross-references and differences (RAF-indexed):
    • Uniprot P06396
      • engineered mutation (189)
  • Chain 'B':
    Compound: gelsolin
    Species: Homo sapiens [TaxId:9606]
    Gene: GSN
    Database cross-references and differences (RAF-indexed):
    • Uniprot P06396
      • engineered mutation (189)
  • Heterogens: SO4, GOL, HOH

PDB Chain Sequences:
This PDB entry is not classified in SCOPe 2.08, so the chain sequences below are not included in the ASTRAL sequence sets.

  • Chain 'A':
    Sequence, based on SEQRES records:
    >6q9zA (A:)
mgsshhhhhhssglvprgshmasatasrgasqagapqgrvpearpnsmvvehpeflkagk
epglqiwrvekfdlvpvptnlygdfftgdayvilktvqlrngnlqydlhywlgnecsqde
sgaaaiftvqlddylngravqhrevqgfesatflgyfksglkykkggvasgfkhvvpnev
vvqrlfqvkrrrvvratevpvswesfnngdcfildlgnnihqwcgsnsnryerlkatqvs
kgirdnersgrarvhvseegtepeamlqvlgpkpalpagtedtakedaanrklaklykvs
ngagtmsvslvadenpfaqgalksedcfildhgkdgkifvwkgkqanteerkaalktasd
fitkmdypkqtqvsvlpeggetplfkqffknwrdpdqtdglglsylsshianvervpfda
atlhtstamaaqhgmdddgtgqkqiwriegsnkvpvdpatygqfyggdsyiilynyrhgg
rqgqiiynwqgaqstqdevaasailtaqldeelggtpvqsrvvqgkepahlmslfggkpm
iiykggtsreggqtapastrlfqvransagatravevlpkagalnsndafvlktpsaayl
wvgtgaseaektgaqellrvlraqpvqvaegsepdgfwealggkaayrtsprlkdkkmda
hpprlfacsnkigrfvieevpgelmqedlatddvmlldtwdqvfvwvgkdsqeeekteal
tsakryietdpanrdrrtpitvvkqgfeppsfvgwflgwdddywsvdpldramaelaa

    Sequence, based on observed residues (ATOM records):
    >6q9zA (A:)
hpeflkagkepglqiwrvekfdlvpvptnlygdfftgdayvilktvqlrngnlqydlhyw
lgnecsqdesgaaaiftvqlddylngravqhrevqgfesatflgyfksglkykkggvasg
fkhvvpvvqrlfqvkrrrvvratevpvswesfnngdcfildlgnnihqwcgsnsnryerl
katqvskgirdnersgrarvhvseegtepeamlqvlgpkpalpagtedaanrklaklykv
sngtmsvslvadenpfaqgalksedcfildhgkdgkifvwkgkqanteerkaalktasdf
itkmdypkqtqvsvlpeggetplfkqffknwrdpdqtdglglsylsshianvervpfdaa
tlhtstamaaqhgmdddgtgqkqiwriegsnkvpvdpatygqfyggdsyiilynyrhggr
qgqiiynwqgaqstqdevaasailtaqldeelggtpvqsrvvqgkepahlmslfggkpmi
iykggtsreggqtapastrlfqvransagatravevlpkagalnsndafvtpsaaylwvg
tgaseaektgaqellrvlqpvqvaegsepdgfweaaayrtsprlkdkkmdahpprlfacs
nkigrfvieevpgelmqedlatddvmlldtwdqvfvwvgkdsqeeektealtsakryiet
dpanrdrrtpitvvkqgfeppsfvgwflgwdddywsvdpldramaela

  • Chain 'B':
    Sequence, based on SEQRES records:
    >6q9zB (B:)
mgsshhhhhhssglvprgshmasatasrgasqagapqgrvpearpnsmvvehpeflkagk
epglqiwrvekfdlvpvptnlygdfftgdayvilktvqlrngnlqydlhywlgnecsqde
sgaaaiftvqlddylngravqhrevqgfesatflgyfksglkykkggvasgfkhvvpnev
vvqrlfqvkrrrvvratevpvswesfnngdcfildlgnnihqwcgsnsnryerlkatqvs
kgirdnersgrarvhvseegtepeamlqvlgpkpalpagtedtakedaanrklaklykvs
ngagtmsvslvadenpfaqgalksedcfildhgkdgkifvwkgkqanteerkaalktasd
fitkmdypkqtqvsvlpeggetplfkqffknwrdpdqtdglglsylsshianvervpfda
atlhtstamaaqhgmdddgtgqkqiwriegsnkvpvdpatygqfyggdsyiilynyrhgg
rqgqiiynwqgaqstqdevaasailtaqldeelggtpvqsrvvqgkepahlmslfggkpm
iiykggtsreggqtapastrlfqvransagatravevlpkagalnsndafvlktpsaayl
wvgtgaseaektgaqellrvlraqpvqvaegsepdgfwealggkaayrtsprlkdkkmda
hpprlfacsnkigrfvieevpgelmqedlatddvmlldtwdqvfvwvgkdsqeeekteal
tsakryietdpanrdrrtpitvvkqgfeppsfvgwflgwdddywsvdpldramaelaa

    Sequence, based on observed residues (ATOM records):
    >6q9zB (B:)
hpeflkagkepglqiwrvekfdlvpvptnlygdfftgdayvilktvqlrngnlqydlhyw
lgnecsqdesgaaaiftvqlddylngravqhrevqgfesatflgyfksglkykkggvasg
fkhvvpnevvvqrlfqvkrrrvvratevpvswesfnngdcfildlgnnihqwcgsnsnry
erlkatqvskgirdnersgrarvhvseegtepeamlqvlgpkpalpagtdaanrklakly
kvsngagtmsvslvadenpfaqgalksedcfildhgkdgkifvwkgkqanteerkaalkt
asdfitkmdypkqtqvsvlpeggetplfkqffknwrdpdlglsylsshianvervpfdaa
tlhtstamaaqhgmdddgtgqkqiwriegsnkvpvdpatygqfyggdsyiilynyrhggr
qgqiiynwqgaqstqdevaasailtaqldeelggtpvqsrvvqgkepahlmslfggkpmi
iykggtsreggqtapastrlfqvransagatravevlpkagalnsndafvlktpsaaylw
vgtgaseaektgaqellrvlraqpvqvaegsepdgfwealggkaayrtsprlkdkkmdah
pprlfacsnkigrfvieevpgelmqedlatddvmlldtwdqvfvwvgkdsqeeektealt
sakryietdpanrdrrtpitvvkqgfeppsfvgwflgwdddywsvdpldramaela