PDB entry 6q84

View 6q84 on RCSB PDB site
Description: crystal structure of rangtp-pdr6-eif5a export complex
Deposited on 2018-12-14, released 2019-05-01
The last revision was dated 2019-06-12, with a file datestamp of 2019-06-07.
Experiment type: XRAY
Resolution: 3.7 Å
R-factor: N/A
AEROSPACI score: 0.08 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Importin beta-like protein KAP122
    Species: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) [TaxId:559292]
    Gene: KAP122, PDR6, YGL016W
    Database cross-references and differences (RAF-indexed):
  • Chain 'B':
    Compound: GTP-binding nuclear protein ran
    Species: Homo sapiens [TaxId:9606]
    Gene: RAN, ARA24, OK/SW-cl.81
    Database cross-references and differences (RAF-indexed):
    • Uniprot P62826
      • engineered mutation (64)
  • Chain 'C':
    Compound: Eukaryotic translation initiation factor 5A-1
    Species: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) [TaxId:559292]
    Gene: HYP2, TIF51A, YEL034W, SYGP-ORF21
    Database cross-references and differences (RAF-indexed):
  • Chain 'D':
    Compound: Importin beta-like protein KAP122
    Species: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) [TaxId:559292]
    Gene: KAP122, PDR6, YGL016W
    Database cross-references and differences (RAF-indexed):
  • Chain 'E':
    Compound: GTP-binding nuclear protein ran
    Species: Homo sapiens [TaxId:9606]
    Gene: RAN, ARA24, OK/SW-cl.81
    Database cross-references and differences (RAF-indexed):
    • Uniprot P62826
      • engineered mutation (64)
  • Chain 'F':
    Compound: Eukaryotic translation initiation factor 5A-1
    Species: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) [TaxId:559292]
    Gene: HYP2, TIF51A, YEL034W, SYGP-ORF21
    Database cross-references and differences (RAF-indexed):
  • Heterogens: GTP, MG

PDB Chain Sequences:
This PDB entry is not classified in SCOPe 2.08, so the chain sequences below are not included in the ASTRAL sequence sets.

  • Chain 'A':
    Sequence, based on SEQRES records:
    >6q84A (A:)
ssihevvalieelysphpkhdvnqiqqslqsiqkseqgfhlanellsddkysanvkyfga
ltltvqlntrgendyetlwnvfrsnllyltkfstlyvsnpnmygqsliiikklmsnlsli
ftkindpqlnnagnenmikqwnnpintfiqlmsvqnqninadqllldsincsltyeqlsq
fvslsqkhnelaltftevivedltkfqtkrhsmsqihevvhehlyistmalinlnltaqa
vfnptvfdcitawinyisltrsvsssgrmdlseifqnlidlmyqstegsdgyenaekilt
ifgnvfandpllmsydlrqqieciflgvvrpdsgitdisnknswmlqymnylvtndffse
lkelaicivdflqintlsvcnklftniqaadngqvqdeyiqeyikvllqmtnfpltpvlq
effsvrmvdfwldlsdaytnlasetlrpnsielstqifqqliniylpkislsvkqriiee
egestsvnefedfrnavsdlaqslwsilgndnltnvlidgmgqmpaasdetliikdtdvl
frietmcfvlntilvdmtlsespwiknivdankffnqnvisvfqtgfqtsastkvsqilk
ldfvrtsttligtlagyfkqepfqlnpyvealfqglhtctnftskneqekisndklevmv
iktvstlcetcreeltpylmhfisflntvimpdsnvshftrtklvrsigyvvqcqvsngp
eeqakyilqltnllsgsiehclassvqlqeqqdyincllyciselatsliqpteiienda
llqrlsefqsfwssdplqirskimctidkvldnsiycknsafveigclivgkglnlpdge
pyflkynmsevmnfvlrhvpncelatclpyfvylleklisefrkeltpqefdfmfekill
vyydayiindpdllqmtigfvnnvldvkpglaigskhwtsfilpqflklipsrekftiva
vakfwtklinnkkynqeelttvrqqvssiggdlvyqimyglfhtqrsdlnsytdllralv
akfpiearewlvavlpqicnnpaghekfinkllitrgsraagnvilqwwldcttlpnyqg

    Sequence, based on observed residues (ATOM records):
    >6q84A (A:)
sihevvalieelysphpkhdvnqiqqslqsiqkseqgfhlanellsddkysanvkyfgal
tltvqlntlwnvfrsnllyltkfstlyvsnpnmygqsliiikklmsnlsliftkindpqn
mikqwnnpintfiqlmsvadqllldsincsltyeqlsqfvslsqkhnelaltftevived
ltkfqtkrhsmsqihevvhehlyistmalinlnltaqavfnptvfdcitawinyisltrr
mdlseifqnlidlmyqstegsdgyenaekiltifgnvfandpllmsydlrqqieciflgn
swmlqymnylvtndffselkelaicivdflqintlsvcnklftniqaadngqvqdeyiqe
yikvllqmtnfpltpvlqeffsvrmvdfwldlsdaytnlasetlrpnsielstqifqqli
niylpkislsvkqriieeegestsvnefedfrnavsdlaqslwsilgndnltnvlidgmg
qmpaasdetliikdtdvlfrietmcfvlntilvdmtlsespwiknivdankffnqnvisv
fqtgfqtsastkvsqilkldfvrtsttligtlagyfkqepfqlnpyvealfqglhtctnf
tskneqekisndklevmviktvstlcetcreeltpylmhfisflntvimpdsnvshftrt
klvrsigyvvqcqvsngpeeqakyilqltnllsgsiehclassvqlqeqqdyincllyci
selatsliqptelsefqsfwssdplqirskimctidkvldnsiycknsafveigclivgk
glnlpdgepyflkynmsevmnfvlrhvpncelatclpyfvylleklisefrkeltpqefd
fmfekillvyydayiindpdllqmtigfvnnvldvkpglaigskhwtsfilpqflklips
rekftivavakfwtklinnkkynqeelttvrqqvssiggdlvyqimyglfhtqrsdlnsy
tdllralvakfpiearewlvavlpqiaghekfinkllitrgsraagnvilqwwldcttl

  • Chain 'B':
    Sequence, based on SEQRES records:
    >6q84B (B:)
gepqvqfklvlvgdggtgkttfvkrhltgefekkyvatlgvevhplvfhtnrgpikfnvw
dtaglekfgglrdgyyiqaqcaiimfdvtsrvtyknvpnwhrdlvrvcenipivlcgnkv
dikdrkvkaksivfhrkknlqyydisaksnynfekpflwlarkligdpnlefvamp

    Sequence, based on observed residues (ATOM records):
    >6q84B (B:)
qvqfklvlvgdggtgkttfvkrhltgefekkyvatlgvevhplvfhtnrgpikfnvwdta
glekfgglrdgyyiqaqcaiimfdvtsrvtyknvpnwhrdlvrvcenipivlcgnkvdik
drkvkaksivfhrkknlqyydisaksnynfekpflwlarkligdpnlefva

  • Chain 'C':
    Sequence, based on SEQRES records:
    >6q84C (C:)
satypmqcsalrkngfvviksrpckivdmstsktgkhghakvhlvaidiftgkkledlsp
sthnmevpvvkrneyqlldiddgflslmnmdgdtkddvkapegelgdslqtafdegkdlm
vtiisamgeeaaisfkeaartd

    Sequence, based on observed residues (ATOM records):
    >6q84C (C:)
atypmqcsalrkngfvviksrpckivdmstsktgkhghakvhlvaidiftgkkledlsps
thnmevpvvkrneyqlldiddgflslmnmdgdtkddvkapegelgdslqtafdegkdlmv
tiisamgeeaaisfkea

  • Chain 'D':
    Sequence, based on SEQRES records:
    >6q84D (D:)
ssihevvalieelysphpkhdvnqiqqslqsiqkseqgfhlanellsddkysanvkyfga
ltltvqlntrgendyetlwnvfrsnllyltkfstlyvsnpnmygqsliiikklmsnlsli
ftkindpqlnnagnenmikqwnnpintfiqlmsvqnqninadqllldsincsltyeqlsq
fvslsqkhnelaltftevivedltkfqtkrhsmsqihevvhehlyistmalinlnltaqa
vfnptvfdcitawinyisltrsvsssgrmdlseifqnlidlmyqstegsdgyenaekilt
ifgnvfandpllmsydlrqqieciflgvvrpdsgitdisnknswmlqymnylvtndffse
lkelaicivdflqintlsvcnklftniqaadngqvqdeyiqeyikvllqmtnfpltpvlq
effsvrmvdfwldlsdaytnlasetlrpnsielstqifqqliniylpkislsvkqriiee
egestsvnefedfrnavsdlaqslwsilgndnltnvlidgmgqmpaasdetliikdtdvl
frietmcfvlntilvdmtlsespwiknivdankffnqnvisvfqtgfqtsastkvsqilk
ldfvrtsttligtlagyfkqepfqlnpyvealfqglhtctnftskneqekisndklevmv
iktvstlcetcreeltpylmhfisflntvimpdsnvshftrtklvrsigyvvqcqvsngp
eeqakyilqltnllsgsiehclassvqlqeqqdyincllyciselatsliqpteiienda
llqrlsefqsfwssdplqirskimctidkvldnsiycknsafveigclivgkglnlpdge
pyflkynmsevmnfvlrhvpncelatclpyfvylleklisefrkeltpqefdfmfekill
vyydayiindpdllqmtigfvnnvldvkpglaigskhwtsfilpqflklipsrekftiva
vakfwtklinnkkynqeelttvrqqvssiggdlvyqimyglfhtqrsdlnsytdllralv
akfpiearewlvavlpqicnnpaghekfinkllitrgsraagnvilqwwldcttlpnyqg

    Sequence, based on observed residues (ATOM records):
    >6q84D (D:)
sihevvalieelysphpkhdvnqiqqslqsiqkseqgfhlanellsddkysanvkyfgal
tltvqlntlwnvfrsnllyltkfstlyvsnpnmygqsliiikklmsnlsliftkindpqq
wnnpintfiqlmsvadqllldsincsltyeqlsqfvslsqkhnelaltftevivedltkf
qtkrhsmsqihevvhehlyistmalinlnltaqavfnptvfdcitawinyisltrsvsss
grmdlseifqnlidlmyqstegsdgyenaekiltifgnvfandpllmsydlrqqiecifl
gnswmlqymnylvtndffselkelaicivdflqintlsvcnklftqvqdeyiqeyikvll
qmtnfpltpvlqeffsvrmvdfwldlsdaytnlasetlrpnsielstqifqqliniylpk
islsvkqriieeegestsvnefedfrnavsdlaqslwsilgndnltnvlidgmgqmpaas
detliikdtdvlfrietmcfvlntilvdmtlsespwiknivdankffnqnvisvfqtgfq
tsastkvsqilkldfvrtsttligtlagyfkqepfqlnpyvealfqglhtctnftskneq
ekisndklevmviktvstlcetcreeltpylmhfisflntvimpdsnvshftrtklvrsi
gyvvqcqvsngpeeqakyilqltnllsgsiehclassvqlqeqqdyincllyciselats
liqptellqrlsefqsfwssdplqirskimctidkvldnsiycknsafveigclivgkgl
nlpdgepyflkynmsevmnfvlrhvpncelatclpyfvylleklisefrkeltpqefdfm
fekillvyydayiindpdllqmtigfvnnvldvkpglaigskhwtsfilpqflklipsre
kftivavakfwtklinnkkynqeelttvrqqvssiggdlvyqimyglfhtqrsdlnsytd
llralvakfpiearewlvavlpqiaghekfinkllitrgsraagnvilqwwldcttl

  • Chain 'E':
    Sequence, based on SEQRES records:
    >6q84E (E:)
gepqvqfklvlvgdggtgkttfvkrhltgefekkyvatlgvevhplvfhtnrgpikfnvw
dtaglekfgglrdgyyiqaqcaiimfdvtsrvtyknvpnwhrdlvrvcenipivlcgnkv
dikdrkvkaksivfhrkknlqyydisaksnynfekpflwlarkligdpnlefvamp

    Sequence, based on observed residues (ATOM records):
    >6q84E (E:)
qvqfklvlvgdggtgkttfvkrhltgefekkyvatlgvevhplvfhtnrgpikfnvwdta
glekfgglrdgyyiqaqcaiimfdvtsrvtyknvpnwhrdlvrvcenipivlcgnkvdik
drkvkaksivfhrkknlqyydisaksnynfekpflwlarkligdpnlefva

  • Chain 'F':
    Sequence, based on SEQRES records:
    >6q84F (F:)
satypmqcsalrkngfvviksrpckivdmstsktgkhghakvhlvaidiftgkkledlsp
sthnmevpvvkrneyqlldiddgflslmnmdgdtkddvkapegelgdslqtafdegkdlm
vtiisamgeeaaisfkeaartd

    Sequence, based on observed residues (ATOM records):
    >6q84F (F:)
typmqcsalrkngfvviksrpckivdmstvhlvaidiftgkkledlspsthnmevpvvkr
neyqlldiddgflslmnmdgdtkddvkapegelgdslqtafdegkdlmvtiisamgeeaa
isfkea