PDB entry 6q7c

View 6q7c on RCSB PDB site
Description: Crystal Structure of Ephrin A2 (EphA2) Receptor Protein Kinase with the NVP-BHG712 derivative ATDL11
Class: transferase
Keywords: Inhibitor, Complex, Protein Tyrosine Kinase, Transferase
Deposited on 2018-12-13, released 2020-01-15
The last revision prior to the SCOPe 2.08 freeze date was dated 2020-01-15, with a file datestamp of 2020-01-10.
Experiment type: XRAY
Resolution: 1.05 Å
R-factor: N/A
AEROSPACI score: 0.77 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Ephrin type-A receptor 2
    Species: Homo sapiens [TaxId:9606]
    Gene: EPHA2, ECK
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d6q7ca_
  • Heterogens: HOK, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >6q7cA (A:)
gdpnqavlkftteihpscvtrqkvigagefgevykgmlktssgkkevpvaiktlkagyte
kqrvdflgeagimgqfshhniirlegviskykpmmiiteymengaldkflrekdgefsvl
qlvgmlrgiaagmkylanmnyvhrdlaarnilvnsnlvckvsdfglsrvleddpeatytt
sggkipirwtapeaisyrkftsasdvwsfgivmwevmtygerpywelsnhevmkaindgf
rlptpmdcpsaiyqlmmqcwqqerarrpkfadivsildklirapdslktladfdprvsir
lpstsg

    Sequence, based on observed residues (ATOM records): (download) 
    >6q7cA (A:)
qavlkftteihpscvtrqkvigafgevykgmlktkevpvaiktlkagytekqrvdflgea
gimgqfshhniirlegviskykpmmiiteymengaldkflrekdgefsvlqlvgmlrgia
agmkylanmnyvhrdlaarnilvnsnlvckvsdfglsgkipirwtapeaisyrkftsasd
vwsfgivmwevmtygerpywelsnhevmkaindgfrlptpmdcpsaiyqlmmqcwqqera
rrpkfadivsildklirapdslktladfdprvsirlp