PDB entry 6q4e

View 6q4e on RCSB PDB site
Description: CDK2 in complex with FragLite33
Class: cell cycle
Keywords: Fragment, FragLite, CDK2, inhibitor, CELL CYCLE
Deposited on 2018-12-05, released 2019-03-20
The last revision prior to the SCOPe 2.08 freeze date was dated 2019-04-24, with a file datestamp of 2019-04-19.
Experiment type: XRAY
Resolution: 1.06 Å
R-factor: N/A
AEROSPACI score: 0.76 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: cyclin-dependent kinase 2
    Species: Homo sapiens [TaxId:9606]
    Gene: CDK2, CDKN2
    Database cross-references and differences (RAF-indexed):
    • Uniprot P24941 (8-305)
      • expression tag (7)
    Domains in SCOPe 2.08: d6q4ea1, d6q4ea2
  • Heterogens: HH5, DMS, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >6q4eA (A:)
gplgspefmenfqkvekigegtygvvykarnkltgevvalkkirldtetegvpstairei
sllkelnhpnivklldvihtenklylvfeflhqdlkkfmdasaltgiplpliksylfqll
qglafchshrvlhrdlkpqnllintegaikladfglarafgvpvrtythevvtlwyrape
illgckyystavdiwslgcifaemvtrralfpgdseidqlfrifrtlgtpdevvwpgvts
mpdykpsfpkwarqdfskvvppldedgrsllsqmlhydpnkrisakaalahpffqdvtkp
vphlrl

    Sequence, based on observed residues (ATOM records): (download) 
    >6q4eA (A:)
fmenfqkvekigegtygvvykarnkltgevvalkkirlpstaireisllkelnhpnivkl
ldvihtenklylvfeflhqdlkkfmdasaltgiplpliksylfqllqglafchshrvlhr
dlkpqnllintegaikladfglarafgevvtlwyrapeillgckyystavdiwslgcifa
emvtrralfpgdseidqlfrifrtlgtpdevvwpgvtsmpdykpsfpkwarqdfskvvpp
ldedgrsllsqmlhydpnkrisakaalahpffqdvtkpvphlrl