PDB entry 6q3w

View 6q3w on RCSB PDB site
Description: Structure of human galactokinase 1 bound with Ethyl 1-(2-pyrazinyl)-4-piperidinecarboxylate
Class: transferase
Keywords: GALK1, fragment, fragment-bound, galactokinase 1, sugar kinase, TRANSFERASE
Deposited on 2018-12-04, released 2019-01-23
The last revision prior to the SCOPe 2.08 freeze date was dated 2020-07-29, with a file datestamp of 2020-06-29.
Experiment type: XRAY
Resolution: 1.96 Å
R-factor: N/A
AEROSPACI score: 0.4 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Galactokinase
    Species: Homo sapiens [TaxId:9606]
    Gene: GALK1, GALK
    Database cross-references and differences (RAF-indexed):
    • Uniprot P51570 (0-390)
      • conflict (250-251)
    Domains in SCOPe 2.08: d6q3wa1, d6q3wa2
  • Chain 'B':
    Compound: Galactokinase
    Species: Homo sapiens [TaxId:9606]
    Gene: GALK1, GALK
    Database cross-references and differences (RAF-indexed):
    • Uniprot P51570 (0-390)
      • conflict (250-251)
    Domains in SCOPe 2.08: d6q3wb1, d6q3wb2
  • Chain 'C':
    Compound: Galactokinase
    Species: Homo sapiens [TaxId:9606]
    Gene: GALK1, GALK
    Database cross-references and differences (RAF-indexed):
    • Uniprot P51570 (0-390)
      • conflict (250-251)
    Domains in SCOPe 2.08: d6q3wc1, d6q3wc2
  • Chain 'D':
    Compound: Galactokinase
    Species: Homo sapiens [TaxId:9606]
    Gene: GALK1, GALK
    Database cross-references and differences (RAF-indexed):
    • Uniprot P51570 (Start-390)
      • conflict (250-251)
    Domains in SCOPe 2.08: d6q3wd1, d6q3wd2
  • Heterogens: GAL, HFK, HGE, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >6q3wA (A:)
aalrqpqvaellaearrafreefgaepelavsapgrvnligehtdynqglvlpmalelmt
vlvgsprkdglvsllttsegadepqrlqfplptaqrslepgtprwanyvkgviqyypaap
lpgfsavvvssvplggglsssaslevatytflqqlcpdsgtiaaraqvcqqaehsfagmp
cgimdqfislmgqkghallidcrsletslvplsdpklavlitnsnvrhslasseypvrrr
qceevaralgaaslrevqleeleaardlvskegfrrarhvvgeirrtaqaaaalrrgdyr
afgrlmveshrslrddyevscpeldqlveaalavpgvygsrmtgggfggctvtlleasaa
phamrhiqehyggtatfylsqaadgakvlcl

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >6q3wB (B:)
aalrqpqvaellaearrafreefgaepelavsapgrvnligehtdynqglvlpmalelmt
vlvgsprkdglvsllttsegadepqrlqfplptaqrslepgtprwanyvkgviqyypaap
lpgfsavvvssvplggglsssaslevatytflqqlcpdsgtiaaraqvcqqaehsfagmp
cgimdqfislmgqkghallidcrsletslvplsdpklavlitnsnvrhslasseypvrrr
qceevaralgaaslrevqleeleaardlvskegfrrarhvvgeirrtaqaaaalrrgdyr
afgrlmveshrslrddyevscpeldqlveaalavpgvygsrmtgggfggctvtlleasaa
phamrhiqehyggtatfylsqaadgakvlcl

    Sequence, based on observed residues (ATOM records): (download) 
    >6q3wB (B:)
aalrqpqvaellaearrafreefgaepelavsapgrvnligehtdynqglvlpmalelmt
vlvgsprglvsllttsegadepqrlqfplptaqrslepgtprwanyvkgviqyypaaplp
gfsavvvssvplggglsssaslevatytflqqlcpdsgtiaaraqvcqqaehsfagmpcg
imdqfislmgqkghallidcrsletslvplsdpklavlitnsnvrhseypvrrrqceeva
ralgaaslrevqleeleaardlvskegfrrarhvvgeirrtaqaaaalrrgdyrafgrlm
veshrslrddyevscpeldqlveaalavpgvygsrmtgggfggctvtlleasaaphamrh
iqehyggtatfylsqaadgakvlcl

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >6q3wC (C:)
aalrqpqvaellaearrafreefgaepelavsapgrvnligehtdynqglvlpmalelmt
vlvgsprkdglvsllttsegadepqrlqfplptaqrslepgtprwanyvkgviqyypaap
lpgfsavvvssvplggglsssaslevatytflqqlcpdsgtiaaraqvcqqaehsfagmp
cgimdqfislmgqkghallidcrsletslvplsdpklavlitnsnvrhslasseypvrrr
qceevaralgaaslrevqleeleaardlvskegfrrarhvvgeirrtaqaaaalrrgdyr
afgrlmveshrslrddyevscpeldqlveaalavpgvygsrmtgggfggctvtlleasaa
phamrhiqehyggtatfylsqaadgakvlcl

    Sequence, based on observed residues (ATOM records): (download) 
    >6q3wC (C:)
aalrqpqvaellaearrafreefgaepelavsapgrvnligehtdynqglvlpmalelmt
vlvgsprkdglvsllttsegadepqrlqfplptaqrslepgtprwanyvkgviqyypaap
lpgfsavvvssvplggglsssaslevatytflqqlcpdsgtiaaraqvcqqaehsfagmp
cgimdqfislmgqkghallidcrsletslvplsdpklavlitnsnvrhslasseypvrrr
qceevaralgaaslrevqleeleaardlvskefrrarhvvgeirrtaqaaaalrrgdyra
fgrlmveshrslrddyevscpeldqlveaalavpgvygsrmtgggfggctvtlleasaap
hamrhiqehyggtatfylsqaadgakvlcl

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >6q3wD (D:)
aalrqpqvaellaearrafreefgaepelavsapgrvnligehtdynqglvlpmalelmt
vlvgsprkdglvsllttsegadepqrlqfplptaqrslepgtprwanyvkgviqyypaap
lpgfsavvvssvplggglsssaslevatytflqqlcpdsgtiaaraqvcqqaehsfagmp
cgimdqfislmgqkghallidcrsletslvplsdpklavlitnsnvrhslasseypvrrr
qceevaralgaaslrevqleeleaardlvskegfrrarhvvgeirrtaqaaaalrrgdyr
afgrlmveshrslrddyevscpeldqlveaalavpgvygsrmtgggfggctvtlleasaa
phamrhiqehyggtatfylsqaadgakvlcl

    Sequence, based on observed residues (ATOM records): (download) 
    >6q3wD (D:)
qvaellaeepelavsapgrvnligehtdynqglvlpmalelmtvlvgspglvsllttqrl
qfplptaqrslepgtprwanyvkgviqyypaaplpgfsavvvssvplggglsssasleva
tytflqqlcpdsgtiaaraqvcqqaehsfmdqfislmgqkghallidcrsletslvplsd
pklavlitnsnvrhslasseypvrrrqceevaralgaaslrevqleeleaardlvskegf
rrarhvvgeirrtaqaaaalrrgdyrafgrlmveshrslrddyevscpeldqlveaalav
pgvygsrmtgggfggctvtlleasaaphamrhiqehyggtatfylsqaadgakvlcl