PDB entry 6q35

View 6q35 on RCSB PDB site
Description: Crystal structure of GES-5 beta-lactamase in complex with boronic inhibitor cpd 3
Class: hydrolase
Keywords: beta-lactamase; bacterial resistance; acyclic boronic inhibitors, HYDROLASE
Deposited on 2018-12-03, released 2019-04-24
The last revision prior to the SCOPe 2.08 freeze date was dated 2019-05-01, with a file datestamp of 2019-04-26.
Experiment type: XRAY
Resolution: 1.4 Å
R-factor: N/A
AEROSPACI score: 0.53 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Beta-lactamase
    Species: Klebsiella pneumoniae [TaxId:573]
    Gene: blaGES-5, pGES-GZ_027
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d6q35a_
  • Chain 'B':
    Compound: Beta-lactamase
    Species: Klebsiella pneumoniae [TaxId:573]
    Gene: blaGES-5, pGES-GZ_027
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d6q35b_
  • Heterogens: EDO, HD5, DMS, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >6q35A (A:)
asekltfktdleklerekaaqigvaivdpqgeivaghrmaqrfamcstfkfplaalvfer
idsgtergdrklsygpdmivewspaterflasghmtvleaaqaavqlsdngatnlllrei
ggpaamtqyfrkigdsvsrldrkepemsdntpgdlrdtttpiamartvakvlyggaltst
sthtierwlignqtgdatlragfpkdwvvgektgtcanggrndigffkaqerdyavavyt
tapklsaverdelvasvgqvitqlilstdk

    Sequence, based on observed residues (ATOM records): (download) 
    >6q35A (A:)
sekltfktdleklerekaaqigvaivdpqgeivaghrmaqrfamcstfkfplaalvferi
dsgtergdrklsygpdmivewspaterflasghmtvleaaqaavqlsdngatnlllreig
gpaamtqyfrkigdsvsrldrkepemsdntpgdlrdtttpiamartvakvlyggaltsts
thtierwlignqtgdatlragfpkdwvvgektgtcanggrndigffkaqerdyavavytt
apklsaverdelvasvgqvitqlilst

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >6q35B (B:)
asekltfktdleklerekaaqigvaivdpqgeivaghrmaqrfamcstfkfplaalvfer
idsgtergdrklsygpdmivewspaterflasghmtvleaaqaavqlsdngatnlllrei
ggpaamtqyfrkigdsvsrldrkepemsdntpgdlrdtttpiamartvakvlyggaltst
sthtierwlignqtgdatlragfpkdwvvgektgtcanggrndigffkaqerdyavavyt
tapklsaverdelvasvgqvitqlilstdk

    Sequence, based on observed residues (ATOM records): (download) 
    >6q35B (B:)
sekltfktdleklerekaaqigvaivdpqgeivaghrmaqrfamcstfkfplaalvferi
dsgtergdrklsygpdmivewspaterflasghmtvleaaqaavqlsdngatnlllreig
gpaamtqyfrkigdsvsrldrkepemsdntpgdlrdtttpiamartvakvlyggaltsts
thtierwlignqtgdatlragfpkdwvvgektgtcanggrndigffkaqerdyavavytt
apklsaverdelvasvgqvitqlilstd