PDB entry 6q2x

View 6q2x on RCSB PDB site
Description: tead4 (216-434) complexed with yap peptide (60-100) and myristoate (covalently bound) at 2.1a (p41212 crystal form)
Deposited on 2018-12-03, released 2019-07-03
The last revision was dated 2019-10-23, with a file datestamp of 2019-10-18.
Experiment type: XRAY
Resolution: 2.1 Å
R-factor: N/A
AEROSPACI score: 0.29 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Transcriptional enhancer factor TEF-3
    Species: Homo sapiens [TaxId:9606]
    Gene: TEAD4, RTEF1, TCF13L1, TEF3
    Database cross-references and differences (RAF-indexed):
  • Chain 'L':
    Compound: Transcriptional coactivator YAP1
    Species: HOMO SAPIENS, synthetic [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
  • Heterogens: GOL, MYR, HOH

PDB Chain Sequences:
This PDB entry is not classified in SCOPe 2.08, so the chain sequences below are not included in the ASTRAL sequence sets.

  • Chain 'A':
    Sequence, based on SEQRES records:
    >6q2xA (A:)
    gprsvassklwmlefsafleqqqdpdtynkhlfvhigqsspsysdpyleavdirqiydkf
    pekkgglkdlfergpsnafflvkfwadlntniedegssfygvssqyespenmiitcstkv
    csfgkqvvekveteyaryenghysyrihrsplceyminfihklkhlpekymmnsvlenft
    ilqvvtnrdtqetllciayvfevsasehgaqhhiyrlvke
    

    Sequence, based on observed residues (ATOM records):
    >6q2xA (A:)
    rsvassklwmlefsafleqqqdpdtynkhlfvhigleavdirqiydkfpekkgglkdlfe
    rgpsnafflvkfwadlntngssfygvssqyespenmiitcstkvcsfgkqvvekveteya
    ryenghysyrihrsplceyminfihklkhlpekymmnsvlenftilqvvtnrdtqetllc
    iayvfevsasehgaqhhiyrlvk
    

  • Chain 'L':
    Sequence, based on SEQRES records:
    >6q2xL (L:)
    dsetdlealfnavmnpktanvpqtvpmrlrklpdsffkppe
    

    Sequence, based on observed residues (ATOM records):
    >6q2xL (L:)
    dsetdlealfnavmnpktanvpqtvpmrlrklpdsffkpp