PDB entry 6q20

View 6q20 on RCSB PDB site
Description: Crystal structure of human 1E01 Fab in complex with influenza virus neuraminidase from A/Japan/305/1957 (H2N2)
Class: viral protein,hydrolase/immune system
Keywords: broadly protective human antibody, neuraminidase, inhibition, active site, antibody-neuraminidase complex, VIRAL PROTEIN, HYDROLASE-IMMUNE SYSTEM complex
Deposited on 2019-08-06, released 2019-10-23
The last revision prior to the SCOPe 2.07 freeze date was dated 2019-10-23, with a file datestamp of 2019-10-18.
Experiment type: XRAY
Resolution: 2.45 Å
R-factor: N/A
AEROSPACI score: 0.2 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Neuraminidase
    Species: Influenza A virus (strain A/Japan/305/1957 H2N2) [TaxId:387161]
    Gene: NA
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d6q20a_
  • Chain 'H':
    Compound: 1E01 Fab IgG1 heavy chain
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 6Q20
  • Chain 'L':
    Compound: 1E01 Fab kappa light chain
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 6Q20 (Start-215)
    Domains in SCOPe 2.07: d6q20l1, d6q20l2
  • Heterogens: BMA, NAG, MAN, CA, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >6q20A (A:)
gspsrveyrnwskpqcqitgfapfskdnsirlsaggdiwvtrepyvscdpgkcyqfalgq
gttldnkhsngtihdriphrtllmnelgvpfhlgtkqvcvawsssschdgkawlhvcvtg
ddrnatasfiydgrlvdsigswsqnilrtqesecvcingtctvvmtdgsasgradtrilf
ikegkivhisplsgsaqhieecscyprypdvrcicrdnwkgsnrpvidinmedysidssy
vcsglvgdtprnddsssnsncrdpnnergnpgvkgwafdngddvwmgrtiskdsrsgyet
fkviggwstpnsksqvnrqvivdnnnwsgysgifsvegkscinrcfyvelirgrpqetrv
wwtsnsivvfcgtsgtygtgswpdganinfmpi

    Sequence, based on observed residues (ATOM records): (download) 
    >6q20A (A:)
veyrnwskpqcqitgfapfskdnsirlsaggdiwvtrepyvscdpgkcyqfalgqgttld
nkhsngtihdriphrtllmnelgvpfhlgtkqvcvawsssschdgkawlhvcvtgddrna
tasfiydgrlvdsigswsqnilrtqesecvcingtctvvmtdgsasgradtrilfikegk
ivhisplsgsaqhieecscyprypdvrcicrdnwkgsnrpvidinmedysidssyvcsgl
vgdtprnddsssnsncrdpnnergnpgvkgwafdngddvwmgrtiskdsrsgyetfkvig
gwstpnsksqvnrqvivdnnnwsgysgifsvegkscinrcfyvelirgrpqetrvwwtsn
sivvfcgtsgtygtgswpdganinfmpi

  • Chain 'H':
    No sequence available.

  • Chain 'L':
    Sequence, based on SEQRES records: (download) 
    >6q20L (L:)
ddiqltqspsflsasvgdrvtitcrasqdissylawyqqkpgnapklliyaasllqsgvp
srfsafgsgteftltisslqpedfatyycqhlksyplftfgpgtkvdikrtvaapsvfif
ppsdeqlksgtasvvcllnnfypreakvqwkvdnalqsgnsqesvteqdskdstyslsst
ltlskadyekhkvyacevthqglsspvtksfnrgec

    Sequence, based on observed residues (ATOM records): (download) 
    >6q20L (L:)
diqltqspsflsasvgdrvtitcrasqdissylawyqqkpgnapklliyaasllqsgvps
rfsafgsgteftltisslqpedfatyycqhlksyplftfgpgtkvdikrtvaapsvfifp
psdeqlksgtasvvcllnnfypreakvqwkvdnalqsgnsqesvteqdskdstyslsstl
tlskadyekhkvyacevthqglsspvtksfnrgec