PDB entry 6pzr

View 6pzr on RCSB PDB site
Description: Crystal structure of Danio rerio histone deacetylase 6 catalytic domain 2 complexed with Resminostat
Class: hydrolase/hydrolase inhibitor
Keywords: Histone deacetylase, metallohydrolase, HYDROLASE-HYDROLASE INHIBITOR complex
Deposited on 2019-08-01, released 2020-02-05
The last revision prior to the SCOPe 2.08 freeze date was dated 2020-02-05, with a file datestamp of 2020-01-31.
Experiment type: XRAY
Resolution: 2.3 Å
R-factor: N/A
AEROSPACI score: 0.24 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Hdac6 protein
    Species: Danio rerio [TaxId:7955]
    Gene: HDAC6
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d6pzra_
  • Chain 'B':
    Compound: Hdac6 protein
    Species: Danio rerio [TaxId:7955]
    Gene: HDAC6
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d6pzrb_
  • Heterogens: ZN, K, P7D, EDO, IOD, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >6pzrA (A:)
spitglvydqrmmlhhnmwdshhpelpqrisrifsrheelrllsrchriparlateeela
lchsskhisiikssehmkprdlnrlgdeynsifisnesytcallaagscfnsaqailtgq
vrnavaivrppghhaekdtacgfcffntaaltaryaqsitreslrvlivdwdvhhgngtq
hifeeddsvlyislhryedgaffpnsedanydkvglgkgrgynvnipwnggkmgdpeyma
afhhlvmpiarefapelvlvsagfdaargdplggfqvtpegyahlthqlmslaagrvlii
leggynltsisesmsmctsmllgdsppsldhltplktsatvsinnvlrahapfwsslr

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >6pzrB (B:)
spitglvydqrmmlhhnmwdshhpelpqrisrifsrheelrllsrchriparlateeela
lchsskhisiikssehmkprdlnrlgdeynsifisnesytcallaagscfnsaqailtgq
vrnavaivrppghhaekdtacgfcffntaaltaryaqsitreslrvlivdwdvhhgngtq
hifeeddsvlyislhryedgaffpnsedanydkvglgkgrgynvnipwnggkmgdpeyma
afhhlvmpiarefapelvlvsagfdaargdplggfqvtpegyahlthqlmslaagrvlii
leggynltsisesmsmctsmllgdsppsldhltplktsatvsinnvlrahapfwsslr

    Sequence, based on observed residues (ATOM records): (download) 
    >6pzrB (B:)
spitglvydqrmmlhhnmwdshhpelpqrisrifsrheelrllsrchriparlateeela
lchsskhisiikssehmkprdlnrlgdeynsifisnesytcallaagscfnsaqailtgq
vrnavaivrppghhaekdtacgfcffntaaltaryaqsitreslrvlivdwdvhhgngtq
hifeeddsvlyislhryedgaffpnsedanydkvglgkgrgynvnipwnggkmgdpeyma
afhhlvmpiarefapelvlvsagfdaargdplggfqvtpegyahlthqlmslaagrvlii
leggynltsisesmsmctsmllgdsppsldhltplktsatvsinnvlrahapfwssl