PDB entry 6pza

View 6pza on RCSB PDB site
Description: cryo-em structure of the pancreatic beta-cell sur1 bound to atp and glibenclamide
Deposited on 2019-07-31, released 2019-08-14
The last revision was dated 2020-10-07, with a file datestamp of 2020-10-02.
Experiment type: EM
Resolution: 3.74 Å
R-factor: N/A
AEROSPACI score: 0.15 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'C':
    Compound: ATP-binding cassette sub-family C member 8
    Species: Cricetus cricetus [TaxId:10034]
    Gene: ABCC8, SUR
    Database cross-references and differences (RAF-indexed):
  • Chain 'D':
    Compound: ATP-sensitive inward rectifier potassium channel 11
    Species: Rattus norvegicus [TaxId:10116]
    Gene: Kcnj11
    Database cross-references and differences (RAF-indexed):
  • Heterogens: GBM, ATP

PDB Chain Sequences:
This PDB entry is not classified in SCOPe 2.08, so the chain sequences below are not included in the ASTRAL sequence sets.

  • Chain 'C':
    Sequence, based on SEQRES records:
    >6pzaC (C:)
mplafcgtenhsaayrvdqgvlnngcfvdalnvvphvfllfitfpilfigwgsqsskvhi
hhstwlhfpghnlrwiltfillfvlvceiaegilsdgvtesrhlhlympagmafmaaits
vvyyhnietsnfpkllialliywtlafitktikfvkfydhaigfsqlrfcltgllvilyg
mlllvevnvirvrryiffktprevkppedlqdlgvrflqpfvnllskgtywwmnafikta
hkkpidlraiaklpiamraltnyqrlcvafdaqarkdtqspqgaraiwralchafgrrli
lsstfriladllgfagplcifgivdhlgkenhvfqpktqflgvyfvssqeflgnayvlav
llflalllqrtflqasyyvaietginlrgaiqtkiynkimhmstsnlsmgemtagqicnl
vaidtnqlmwffflcpnlwtmpvqiivgvillyyilgvsaligaaviillapvqyfvatk
lsqaqrttlehsnerlkqtnemlrgmkllklyawesifcsrvevtrrkemtslrafavyt
sisifmntaipiaavlitfvghvsffkesdlspsvafaslslfhilvtplfllssvvrst
vkalvsvqklseflssaeireeqcaprepapqgqagkyqavplkvvnrkrpareevrdll
gplqrlapsmdgdadnfcvqiiggfftwtpdgiptlsnitiriprgqltmivgqvgcgks
slllatlgemqkvsgavfwnsnlpdsegedpssperetaagsdirsrgpvayasqkpwll
natveenitfespfnkqrykmvieacslqpdidilphgdqtqigerginlsggqrqrisv
aralyqqtnvvflddpfsaldvhlsdhlmqagilellrddkrtvvlvthklqylphadwi
iamkdgtiqregtlkdfqrsecqlfehwktlmnrqdqeleketvmerkasepsqglpram
ssrdgllldeeeeeeeaaeseeddnlssvlhqrakipwractkylssagilllsllvfsq
llkhmvlvaidywlakwtdsalvlspaarncslsqecdldqsvyamvftllcslgivlcl
vtsvtvewtglkvakrlhrsllnriilapmrffettplgsilnrfssdcntidqhipstl
eclsrstllcvsaltvisyvtpvflvallplavvcyfiqkyfrvasrdlqqlddttqlpl
vshfaetveglttirafryearfqqklleytdsnniaslfltaanrwlevcmeyigacvv
liaaatsisnslhrelsaglvglgltyalmvsnylnwmvrnladmeiqlgavkrihallk
teaesyegllapslipknwpdqgkiqiqnlsvrydsslkpvlkhvntlispgqkigicgr
tgsgkssfslaffrmvdmfegriiidgidiaklplhtlrsrlsiilqdpvlfsgtirfnl
dpekkcsdstlwealeiaqlklvvkalpggldaiiteggenfsqgqrqlfclarafvrkt
sifimdeatasidmatenilqkvvmtafadrtvvtiahrvhtilsadlvmvlkrgailef
dkpetllsqkdsvfasfvradk

    Sequence, based on observed residues (ATOM records):
    >6pzaC (C:)
mplafcgtenhsaayrvdqgvlnngcfvdalnvvphvfllfitfpilfigwgsqsskvhi
hhstwlhfpghnlrwiltfillfvlvceiaegilsdgvtesrhlhlympagmafmaaits
vvyyhnietsnfpkllialliywtlafitktikfvkfydhaigfsqlrfcltgllvilyg
mlllvevnvirvrryiffktprevkppedlqdlgvrflqpfvnllskgtywwmnafikta
hkkpidlraiaklpiamraltnyqrlcvafdaqarkdtqspqgaraiwralchafgrrli
lsstfriladllgfagplcifgivdhlgkenhvfqpktqflgvyfvssqeflgnayvlav
llflalllqrtflqasyyvaietginlrgaiqtkiynkimhmstsnlsmgemtagqicnl
vaidtnqlmwffflcpnlwtmpvqiivgvillyyilgvsaligaaviillapvqyfvatk
lsqaqrttlehsnerlkqtnemlrgmkllklyawesifcsrvevtrrkemtslrafavyt
sisifmntaipiaavlitfvghvsffkesdlspsvafaslslfhilvtplfllssvvrst
vkalvsvqklseflssaeirecvqiiggfftwtpdgiptlsnitiriprgqltmivgqvg
cgksslllatlgemqkvsgavfwnsnrsrgpvayasqkpwllnatveenitfespfnkqr
ykmvieacslqpdidilphgdqtqigerginlsggqrqrisvaralyqqtnvvflddpfs
aldvhlsdhlmqagilellrddkrtvvlvthklqylphadwiiamkdgtiqregtlkdfq
rsecqlfehwqrakipwractkylssagilllsllvfsqllkhmvlvaidywlakwtdsa
lvldqsvyamvftllcslgivlclvtsvtvewtglkvakrlhrsllnriilapmrffett
plgsilnrfssdcntidqhipstleclsrstllcvsaltvisyvtpvflvallplavvcy
fiqkyfrvasrdlqqlddttqlplvshfaetveglttirafryearfqqklleytdsnni
aslfltaanrwlevcmeyigacvvliaaatsisnslhrelsaglvglgltyalmvsnyln
wmvrnladmeiqlgavkrihallkteaesyegllapslipknwpdqgkiqiqnlsvryds
slkpvlkhvntlispgqkigicgrtgsgkssfslaffrmvdmfegriiidgidiaklplh
tlrsrlsiilqdpvlfsgtirfnldpekkcsdstlwealeiaqlklvvkalpggldaiit
eggenfsqgqrqlfclarafvrktsifimdeatasidmatenilqkvvmtafadrtvvti
ahrvhtilsadlvmvlkrgailefdkpetllsqkdsvfasfv

  • Chain 'D':
    Sequence, based on SEQRES records:
    >6pzaD (D:)
mlsrkgiipeeyvltrlaedptepryrtrerrarfvskkgncnvahknireqgrflqdvf
ttlvdlkwphtlliftmsflcswllfamvwwliafahgdlapgegtnvpcvtsihsfssa
flfsievqvtigfggrmvteecplaililivqnivglminaimlgcifmktaqahrraet
lifskhavitprhgrlcfmlrvgdlrksmiisatihmqvvrkttspegevvplhqvdipm
engvggnsiflvapliiyhvidsnsplydlapsdlhhhqdleiivilegvvettgittqa
rtsyladeilwgqrfvpivaeedgrysvdyskfgntvkvptplctarqldedrslldalt
lassrgplrkrsvavakakpkfsispdsls

    Sequence, based on observed residues (ATOM records):
    >6pzaD (D:)
mlsrkgiipeeyvltrlae