PDB entry 6pya

View 6pya on RCSB PDB site
Description: Sex Hormone-binding globulin mutant E176K in complex with IPI
Class: hormone
Keywords: Sex Steroid Transport Binding Globulin, HORMONE
Deposited on 2019-07-29, released 2019-12-25
The last revision prior to the SCOPe 2.08 freeze date was dated 2020-02-12, with a file datestamp of 2020-02-07.
Experiment type: XRAY
Resolution: 1.71 Å
R-factor: N/A
AEROSPACI score: 0.39 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: sex hormone-binding globulin
    Species: Homo sapiens [TaxId:9606]
    Gene: SHBG
    Database cross-references and differences (RAF-indexed):
    • Uniprot P04278
      • engineered mutation (175)
    Domains in SCOPe 2.08: d6pyaa_
  • Heterogens: P57, CA, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >6pyaA (A:)
lrpvlptqsahdppavhlsngpgqepiavmtfdltkitktsssfevrtwdpegvifygdt
npkddwfmlglrdgrpeiqlhnhwaqltvgagprlddgrwhqvevkmegdsvllevdgee
vlrlrqvsgpltskrhpimrialggllfpasnlrlplvpaldgclrrdswldkqakisas
aptslrscdvesnpgiflppgtqae

    Sequence, based on observed residues (ATOM records): (download) 
    >6pyaA (A:)
pavhlsngpgqepiavmtfdltkitktsssfevrtwdpegvifygdtnpkddwfmlglrd
grpeiqlhnhwaqltvgagprlddgrwhqvevkmegdsvllevdgeevlrlrqvsgplts
krhpimrialggllfpasnlrlplvpaldgclrrdswldkqakisasaptslrsc