PDB entry 6pxp

View 6pxp on RCSB PDB site
Description: Human Casein Kinase 1 delta Site 2 mutant (K171E)
Class: circadian clock protein/transferase
Keywords: Kinase, serine-threonine kinase, CIRCADIAN CLOCK PROTEIN, CIRCADIAN CLOCK PROTEIN-TRANSFERASE complex
Deposited on 2019-07-26, released 2020-02-12
The last revision prior to the SCOPe 2.08 freeze date was dated 2020-08-26, with a file datestamp of 2020-08-21.
Experiment type: XRAY
Resolution: 2.35 Å
R-factor: N/A
AEROSPACI score: 0.3 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Casein kinase I isoform delta
    Species: Homo sapiens [TaxId:9606]
    Gene: CSNK1D, HCKID
    Database cross-references and differences (RAF-indexed):
    • Uniprot P48730
      • engineered mutation (170)
    Domains in SCOPe 2.08: d6pxpa_
  • Chain 'B':
    Compound: Casein kinase I isoform delta
    Species: Homo sapiens [TaxId:9606]
    Gene: CSNK1D, HCKID
    Database cross-references and differences (RAF-indexed):
    • Uniprot P48730 (Start-293)
      • engineered mutation (170)
    Domains in SCOPe 2.08: d6pxpb_
  • Heterogens: SO4, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >6pxpA (A:)
melrvgnryrlgrkigsgsfgdiylgtdiaageevaiklecvktkhpqlhieskiykmmq
ggvgiptirwcgaegdynvmvmellgpsledlfnfcsrkfslktvllladqmisrieyih
sknfihrdvkpdnflmglgkkgnlvyiidfglakkyrdarthqhipyrenenltgtarya
sinthlgieqsrrddleslgyvlmyfnlgslpwqglkaatkrqkyerisekkmstpievl
ckgypsefatylnfcrslrfddkpdysylrqlfrnlfhrqgfsydyvfdwnmlk

    Sequence, based on observed residues (ATOM records): (download) 
    >6pxpA (A:)
elrvgnryrlgrkigsgsfgdiylgtdiaageevaiklecvktkhpqlhieskiykmmqg
gvgiptirwcgaegdynvmvmellgpsledlfnfcsrkfslktvllladqmisrieyihs
knfihrdvkpdnflmglgkkgnlvyiidfglakkyrdarthqhipyrenenltgtaryas
inthlgieqsrrddleslgyvlmyfnlgslpwqglkrqkyerisekkmstpievlckgyp
sefatylnfcrslrfddkpdysylrqlfrnlfhrqgfsydyvfdwnml

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >6pxpB (B:)
melrvgnryrlgrkigsgsfgdiylgtdiaageevaiklecvktkhpqlhieskiykmmq
ggvgiptirwcgaegdynvmvmellgpsledlfnfcsrkfslktvllladqmisrieyih
sknfihrdvkpdnflmglgkkgnlvyiidfglakkyrdarthqhipyrenenltgtarya
sinthlgieqsrrddleslgyvlmyfnlgslpwqglkaatkrqkyerisekkmstpievl
ckgypsefatylnfcrslrfddkpdysylrqlfrnlfhrqgfsydyvfdwnmlk

    Sequence, based on observed residues (ATOM records): (download) 
    >6pxpB (B:)
elrvgnryrlgrkigsgsfgdiylgtdiaageevaiklecvktkhpqlhieskiykmmqg
gvgiptirwcgaegdynvmvmellgpsledlfnfcsrkfslktvllladqmisrieyihs
knfihrdvkpdnflmglgkkgnlvyiidfglakkyrdarthqhipyrenenltgtaryas
inthlgieqsrrddleslgyvlmyfnlgslpwqglkaatkrqkyerisekkmstpievlc
kgypsefatylnfcrslrfddkpdysylrqlfrnlfhrqgfsydyvfdwnmlk