PDB entry 6pxn

View 6pxn on RCSB PDB site
Description: Human Casein Kinase 1 delta Tau mutant (R178C)
Class: circadian clock protein/transferase
Keywords: Kinase, serine-threonine kinase, CIRCADIAN CLOCK PROTEIN, CIRCADIAN CLOCK PROTEIN-TRANSFERASE complex
Deposited on 2019-07-26, released 2020-02-12
The last revision prior to the SCOPe 2.08 freeze date was dated 2020-08-26, with a file datestamp of 2020-08-21.
Experiment type: XRAY
Resolution: 1.55 Å
R-factor: N/A
AEROSPACI score: 0.55 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Casein kinase I isoform delta
    Species: Homo sapiens [TaxId:9606]
    Gene: CSNK1D, HCKID
    Database cross-references and differences (RAF-indexed):
    • Uniprot P48730
      • engineered mutation (177)
    Domains in SCOPe 2.08: d6pxna_
  • Chain 'B':
    Compound: Casein kinase I isoform delta
    Species: Homo sapiens [TaxId:9606]
    Gene: CSNK1D, HCKID
    Database cross-references and differences (RAF-indexed):
    • Uniprot P48730
      • engineered mutation (177)
    Domains in SCOPe 2.08: d6pxnb_
  • Heterogens: SO4, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >6pxnA (A:)
melrvgnryrlgrkigsgsfgdiylgtdiaageevaiklecvktkhpqlhieskiykmmq
ggvgiptirwcgaegdynvmvmellgpsledlfnfcsrkfslktvllladqmisrieyih
sknfihrdvkpdnflmglgkkgnlvyiidfglakkyrdarthqhipyrenknltgtacya
sinthlgieqsrrddleslgyvlmyfnlgslpwqglkaatkrqkyerisekkmstpievl
ckgypsefatylnfcrslrfddkpdysylrqlfrnlfhrqgfsydyvfdwnmlkfgasra
addaererrdreerlrhsrnpatrglpstasgrlrgtqevapptpltptshtantsprpv
sgmererkvsmrlhrgapvnisssdltgrqdtsrmstsqipgrvassglqsvvhr

    Sequence, based on observed residues (ATOM records): (download) 
    >6pxnA (A:)
elrvgnryrlgrkigsgsfgdiylgtdiaageevaiklecvktkhpqlhieskiykmmqg
gvgiptirwcgaegdynvmvmellgpsledlfnfcsrkfslktvllladqmisrieyihs
knfihrdvkpdnflmglgkkgnlvyiidfglakkyrdarthqhipyrenknltgtacyas
inthlgieqsrrddleslgyvlmyfnlgslpwqglkaatkrqkyerisekkmstpievlc
kgypsefatylnfcrslrfddkpdysylrqlfrnlfhrqgfsydyvfdwn

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >6pxnB (B:)
melrvgnryrlgrkigsgsfgdiylgtdiaageevaiklecvktkhpqlhieskiykmmq
ggvgiptirwcgaegdynvmvmellgpsledlfnfcsrkfslktvllladqmisrieyih
sknfihrdvkpdnflmglgkkgnlvyiidfglakkyrdarthqhipyrenknltgtacya
sinthlgieqsrrddleslgyvlmyfnlgslpwqglkaatkrqkyerisekkmstpievl
ckgypsefatylnfcrslrfddkpdysylrqlfrnlfhrqgfsydyvfdwnmlkfgasra
addaererrdreerlrhsrnpatrglpstasgrlrgtqevapptpltptshtantsprpv
sgmererkvsmrlhrgapvnisssdltgrqdtsrmstsqipgrvassglqsvvhr

    Sequence, based on observed residues (ATOM records): (download) 
    >6pxnB (B:)
elrvgnryrlgrkigsgsfgdiylgtdiaageevaiklecvktkhpqlhieskiykmmqg
gvgiptirwcgaegdynvmvmellgpsledlfnfcsrkfslktvllladqmisrieyihs
knfihrdvkpdnflmglgkkgnlvyiidfglakkyrdarthqhipyrenknltgtacyas
inthlgieqsrrddleslgyvlmyfnlgslpwqgatkrqkyerisekkmstpievlckgy
psefatylnfcrslrfddkpdysylrqlfrnlfhrqgfsydyvfdwnmlk