PDB entry 6pxh

View 6pxh on RCSB PDB site
Description: Crystal Structure of MERS-CoV S1-NTD bound with G2 Fab
Class: IMMUNE SYSTEM/Viral protein
Keywords: immune system, antibody, fusion glycoprotein, IMMUNE SYSTEM-Viral protein complex
Deposited on 2019-07-26, released 2019-09-25
The last revision prior to the SCOPe 2.08 freeze date was dated 2020-07-29, with a file datestamp of 2020-07-04.
Experiment type: XRAY
Resolution: 2.3 Å
R-factor: N/A
AEROSPACI score: 0.31 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: MERS-CoV S1-NTD
    Species: Middle East respiratory syndrome-related coronavirus [TaxId:1335626]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d6pxha_
  • Chain 'B':
    Compound: MERS-CoV S1-NTD
    Species: Middle East respiratory syndrome-related coronavirus [TaxId:1335626]
    Database cross-references and differences (RAF-indexed):
    • Uniprot V9TWK2 (0-333)
      • expression tag (334-340)
    Domains in SCOPe 2.08: d6pxhb1, d6pxhb2
  • Chain 'C':
    Compound: G2 heavy chain
    Species: Mus musculus [TaxId:10090]
    Database cross-references and differences (RAF-indexed):
    • PDB 6PXH (0-End)
    Domains in SCOPe 2.08: d6pxhc1, d6pxhc2
  • Chain 'D':
    Compound: G2 light chain
    Species: Mus musculus [TaxId:10090]
    Database cross-references and differences (RAF-indexed):
    • PDB 6PXH (0-217)
    Domains in SCOPe 2.08: d6pxhd1, d6pxhd2
  • Chain 'H':
    Compound: G2 heavy chain
    Species: Mus musculus [TaxId:10090]
    Database cross-references and differences (RAF-indexed):
    • PDB 6PXH (0-End)
    Domains in SCOPe 2.08: d6pxhh1, d6pxhh2
  • Chain 'L':
    Compound: G2 light chain
    Species: Mus musculus [TaxId:10090]
    Database cross-references and differences (RAF-indexed):
    • PDB 6PXH (0-217)
    Domains in SCOPe 2.08: d6pxhl1, d6pxhl2
  • Heterogens: NAG, SO4, DHF, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >6pxhA (A:)
yvdvgpdsvksacievdiqqtffdktwprpidvskadgiiypqgrtysnitityqglfpy
qgdhgdmyvysaghatgttpqklfvanysqdvkqfangfvvrigaaanstgtviispsts
atirkiypafmlgssvgnfsdgkmgrffnhtlvllpdgcgtllrafycileprsgnhcpa
gnsytsfatyhtpatdcsdgnynrnaslnsfkeyfnlrnctfmytynitedeilewfgit
qtaqgvhlfssryvdlyggnmfqfatlpvydtikyysiiphsirsiqsdrkawaafyvyk
lqpltflldfsvdgyirraidcgfndlsqlhcsygslevlfq

    Sequence, based on observed residues (ATOM records): (download) 
    >6pxhA (A:)
yvdvgpdsvksacievdiqqtffdktwprpidvskadgiiypqgrtysnitityqglfpy
qgdhgdmyvysaghatgttpqklfvanysqdvkqfangfvvrigaaanstgtviispsts
atirkiypafmlgssvgnfsdgkmgrffnhtlvllpdgcgtllrafycileprsgnhcpa
gnsytsfatyhtpatdcsdgnynrnaslnsfkeyfnlrnctfmytynitedeilewfgit
qtaqgvhlfssryvdlyggnmfqfatlpvydtikyysiiphsirsiqsdrkawaafyvyk
lqpltflldfsvdgyirraidcgfndlsqlhcsy

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >6pxhB (B:)
yvdvgpdsvksacievdiqqtffdktwprpidvskadgiiypqgrtysnitityqglfpy
qgdhgdmyvysaghatgttpqklfvanysqdvkqfangfvvrigaaanstgtviispsts
atirkiypafmlgssvgnfsdgkmgrffnhtlvllpdgcgtllrafycileprsgnhcpa
gnsytsfatyhtpatdcsdgnynrnaslnsfkeyfnlrnctfmytynitedeilewfgit
qtaqgvhlfssryvdlyggnmfqfatlpvydtikyysiiphsirsiqsdrkawaafyvyk
lqpltflldfsvdgyirraidcgfndlsqlhcsygslevlfq

    Sequence, based on observed residues (ATOM records): (download) 
    >6pxhB (B:)
yvdvgpdsvksacievdiqqtffdktwprpidvskadgiiypqgrtysnitityqglfpy
qgdhgdmyvysaghatgttpqklfvanysqdvkqfangfvvrigaaanstgtviispsts
atirkiypafmlgssvgnfsdgkmgrffnhtlvllpdgcgtllrafycileprsgnhcpa
gnsytsfatyhtpatdcsdgnynrnaslnsfkeyfnlrnctfmytynitedeilewfgit
qtaqgvhlfssryvdlyggnmfqfatlpvydtikyysiiphsirsiqsdrkawaafyvyk
lqpltflldfsvdgyirraidcgfndlsqlhcsygslevlf

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >6pxhC (C:)
qvqlqqsggelvkpgasvklscktsgftfsssyiswlkqkpgqslewiawiyagtggtey
nqkftgkaqvtvdtssstaymqfsslttedsaiyycarggssfamdywgqgtsvtvssas
ttppsvyplapgsaaqtnsmvtlgclvkgyfpepvtvtwnsgslssgvhtfpavlqsdly
tlsssvtvpsstwpsetvtcnvahpasstkvdkkivprdcgkglevlfq

    Sequence, based on observed residues (ATOM records): (download) 
    >6pxhC (C:)
qvqlqqsggelvkpgasvklscktsgftfsssyiswlkqkpgqslewiawiyagtggtey
nqkftgkaqvtvdtssstaymqfsslttedsaiyycarggssfamdywgqgtsvtvssas
ttppsvyplapsmvtlgclvkgyfpepvtvtwnsgslssgvhtfpavlqsdlytlsssvt
vpsstwpsetvtcnvahpasstkvdkkivprdc

  • Chain 'D':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >6pxhD (D:)
qlvltqspaslavslgqratiscrasesvdnygisfmnwfqqkpgqppkllihtasnqgs
gvparfsgsgsgtdfslnihpvedddtamyfcqqseevpltfgagtkleikrtdaaptvs
ifppsseqltsggasvvcflnnfypkdinvkwkidgserqngvlnswtdqdskdstysms
stltltkdeyerhnsytceathktstspivksfnrnec

  • Chain 'H':
    Sequence, based on SEQRES records: (download) 
    >6pxhH (H:)
qvqlqqsggelvkpgasvklscktsgftfsssyiswlkqkpgqslewiawiyagtggtey
nqkftgkaqvtvdtssstaymqfsslttedsaiyycarggssfamdywgqgtsvtvssas
ttppsvyplapgsaaqtnsmvtlgclvkgyfpepvtvtwnsgslssgvhtfpavlqsdly
tlsssvtvpsstwpsetvtcnvahpasstkvdkkivprdcgkglevlfq

    Sequence, based on observed residues (ATOM records): (download) 
    >6pxhH (H:)
qvqlqqsggelvkpgasvklscktsgftfsssyiswlkqkpgqslewiawiyagtggtey
nqkftgkaqvtvdtssstaymqfsslttedsaiyycarggssfamdywgqgtsvtvssas
ttppsvyplapgsaaqtnsmvtlgclvkgyfpepvtvtwnsgslssgvhtfpavlqsdly
tlsssvtvpsstwpsetvtcnvahpasstkvdkkivprdc

  • Chain 'L':
    Sequence, based on SEQRES records: (download) 
    >6pxhL (L:)
qlvltqspaslavslgqratiscrasesvdnygisfmnwfqqkpgqppkllihtasnqgs
gvparfsgsgsgtdfslnihpvedddtamyfcqqseevpltfgagtkleikrtdaaptvs
ifppsseqltsggasvvcflnnfypkdinvkwkidgserqngvlnswtdqdskdstysms
stltltkdeyerhnsytceathktstspivksfnrnec

    Sequence, based on observed residues (ATOM records): (download) 
    >6pxhL (L:)
qlvltqspaslavslgqratiscrasessfmnwfqqkpgqppkllihtasnqgsgvparf
sgsgsgtdfslnihpvedddtamyfcqqseevpltfgagtkleikrtdaaptvsifppss
eqltsggasvvcflnnfypkdinvkwkidgserqngvlnswtdqdskdstysmsstltlt
kdeyerhnsytceathktstspivksfnrnec