PDB entry 6pwf

View 6pwf on RCSB PDB site
Description: cryo-em structure of the atpase domain of chromatin remodeling factor iswi bound to the nucleosome
Deposited on 2019-07-22, released 2019-08-21
The last revision was dated 2019-12-04, with a file datestamp of 2019-11-29.
Experiment type: EM
Resolution: 4.07 Å
R-factor: N/A
AEROSPACI score: 0.05 (click here for full SPACI score report)

Chains and heterogens:

• Chain 'A':
  Compound: histone h3
  Species: Drosophila melanogaster [TaxId:7227]
  Gene: His3, His3:CG31613, CG31613, His3:CG33803, CG33803, His3:CG33806, CG33806, His3:CG33809, CG33809, His3:CG33812, CG33812, His3:CG33815, CG33815, His3:CG33818, CG33818, His3:CG33821, CG33821, His3:CG33824, CG33824, His3:CG33827, CG33827, His3:CG33830, CG33830, His3:CG33833, CG33833, His3:CG33836, CG33836, His3:CG33839, CG33839, His3:CG33842, CG33842, His3:CG33845, CG33845, His3:CG33848, CG33848, His3:CG33851, CG33851, His3:CG33854, CG33854, His3:CG33857, CG33857, His3:CG33860, CG33860, His3:CG33863, CG33863, His3:CG33866, CG33866
  Database cross-references and differences (RAF-indexed):
  • Uniprot P02299
• Chain 'B':
  Compound: histone h4
  Species: Drosophila melanogaster [TaxId:7227]
  Gene: His4r, BcDNA:RH52884, CG3379, DmelCG3379, FBtr0082962, H4r, His4-88CD, His4R, CG3379, Dmel_CG3379
  Database cross-references and differences (RAF-indexed):
  • Uniprot A0A0B4KFZ9 (Start-102)
• Chain 'C':
  Compound: histone h2a
  Species: Drosophila melanogaster [TaxId:7227]
  Gene: His2A, H2a, His2A:CG31618, CG31618, His2A:CG33808, CG33808, His2A:CG33814, CG33814, His2A:CG33817, CG33817, His2A:CG33820, CG33820, His2A:CG33823, CG33823, His2A:CG33826, CG33826, His2A:CG33829, CG33829, His2A:CG33832, CG33832, His2A:CG33835, CG33835, His2A:CG33838, CG33838, His2A:CG33841, CG33841, His2A:CG33844, CG33844, His2A:CG33847, CG33847, His2A:CG33850, CG33850, His2A:CG33862, CG33862, His2A:CG33865, CG33865
  Database cross-references and differences (RAF-indexed):
  • Uniprot P84051
• Chain 'D':
  Compound: histone h2b
  Species: Drosophila melanogaster [TaxId:7227]
  Gene: His2B, His2B:CG17949, CG17949, His2B:CG33868, CG33868, His2B:CG33870, CG33870, His2B:CG33872, CG33872, His2B:CG33874, CG33874, His2B:CG33876, CG33876, His2B:CG33878, CG33878, His2B:CG33880, CG33880, His2B:CG33882, CG33882, His2B:CG33884, CG33884, His2B:CG33886, CG33886, His2B:CG33888, CG33888, His2B:CG33890, CG33890, His2B:CG33892, CG33892, His2B:CG33894, CG33894, His2B:CG33896, CG33896, His2B:CG33898, CG33898, His2B:CG33900, CG33900, His2B:CG33902, CG33902, His2B:CG33904, CG33904, His2B:CG33906, CG33906, His2B:CG33908, CG33908, His2B:CG33910, CG33910
  Database cross-references and differences (RAF-indexed):
  • Uniprot P02283
• Chain 'E':
  Compound: histone h3
  Species: Drosophila melanogaster [TaxId:7227]
  Gene: His3, His3:CG31613, CG31613, His3:CG33803, CG33803, His3:CG33806, CG33806, His3:CG33809, CG33809, His3:CG33812, CG33812, His3:CG33815, CG33815, His3:CG33818, CG33818, His3:CG33821, CG33821, His3:CG33824, CG33824, His3:CG33827, CG33827, His3:CG33830, CG33830, His3:CG33833, CG33833, His3:CG33836, CG33836, His3:CG33839, CG33839, His3:CG33842, CG33842, His3:CG33845, CG33845, His3:CG33848, CG33848, His3:CG33851, CG33851, His3:CG33854, CG33854, His3:CG33857, CG33857, His3:CG33860, CG33860, His3:CG33863, CG33863, His3:CG33866, CG33866
  Database cross-references and differences (RAF-indexed):
  • Uniprot P02299
• Chain 'F':
  Compound: histone h4
  Species: Drosophila melanogaster [TaxId:7227]
  Gene: His4r, BcDNA:RH52884, CG3379, DmelCG3379, FBtr0082962, H4r, His4-88CD, His4R, CG3379, Dmel_CG3379
  Database cross-references and differences (RAF-indexed):
  • Uniprot A0A0B4KFZ9 (Start-102)
• Chain 'G':
  Compound: histone h2a
  Species: Drosophila melanogaster [TaxId:7227]
  Gene: His2A, H2a, His2A:CG31618, CG31618, His2A:CG33808, CG33808, His2A:CG33814, CG33814, His2A:CG33817, CG33817, His2A:CG33820, CG33820, His2A:CG33823, CG33823, His2A:CG33826, CG33826, His2A:CG33829, CG33829, His2A:CG33832, CG33832, His2A:CG33835, CG33835, His2A:CG33838, CG33838, His2A:CG33841, CG33841, His2A:CG33844, CG33844, His2A:CG33847, CG33847, His2A:CG33850, CG33850, His2A:CG33862, CG33862, His2A:CG33865, CG33865
  Database cross-references and differences (RAF-indexed):
  • Uniprot P84051
• Chain 'H':
  Compound: histone h2b
  Species: Drosophila melanogaster [TaxId:7227]
  Gene: His2B, His2B:CG17949, CG17949, His2B:CG33868, CG33868, His2B:CG33870, CG33870, His2B:CG33872, CG33872, His2B:CG33874, CG33874, His2B:CG33876, CG33876, His2B:CG33878, CG33878, His2B:CG33880, CG33880, His2B:CG33882, CG33882, His2B:CG33884, CG33884, His2B:CG33886, CG33886, His2B:CG33888, CG33888, His2B:CG33890, CG33890, His2B:CG33892, CG33892, His2B:CG33894, CG33894, His2B:CG33896, CG33896, His2B:CG33898, CG33898, His2B:CG33900, CG33900, His2B:CG33902, CG33902, His2B:CG33904, CG33904, His2B:CG33906, CG33906, His2B:CG33908, CG33908, His2B:CG33910, CG33910
  Database cross-references and differences (RAF-indexed):
  • Uniprot P02283
• Chain 'I':
  Compound: DNA (147-mer)
  Species: synthetic construct, synthetic [TaxId:32630]
  
• Chain 'J':
  Compound: DNA (147-mer)
  Species: synthetic construct, synthetic [TaxId:32630]
  
• Chain 'K':
  Compound: chromatin remodeling factor ISWI
  Species: CHAETOMIUM THERMOPHILUM [TaxId:209285]
  Gene: CTHT_0046320
  Database cross-references and differences (RAF-indexed):
  • Uniprot G0S9L5
  • Uniprot G0S9L5

PDB Chain Sequences:
This PDB entry is not classified in SCOPe 2.08, so the chain sequences below are not included in the ASTRAL sequence sets.

• Chain 'A':
  Sequence, based on SEQRES records:
  

  >6pwfA (A:)
  martkqtarkstggkaprkqlatkaarksapatggvkkphryrpgtvalreirryqkste
  llirklpfqrlvreiaqdfktdlrfqssavmalqeaseaylvglfedtnlcaihakrvti
  mpkdiqlarrirgera
  

  
  Sequence, based on observed residues (ATOM records):
  

  >6pwfA (A:)
  phryrpgtvalreirryqkstellirklpfqrlvreiaqdfktdlrfqssavmalqease
  aylvglfedtnlcaihakrvtimpkdiqlarrirge
  

  
  
• Chain 'B':
  Sequence, based on SEQRES records:
  

  >6pwfB (B:)
  mtgrgkggkglgkggakrhrkvlrdniqgitkpairrlarrggvkrisgliyeetrgvlk
  vflenvirdavtytehakrktvtamdvvyalkrqgrtlygfgg
  

  
  Sequence, based on observed residues (ATOM records):
  

  >6pwfB (B:)
  akrhrkvlrdniqgitkpairrlarrggvkrisgliyeetrgvlkvflenvirdavtyte
  hakrktvtamdvvyalkrqgrtlygfgg
  

  
  
• Chain 'C':
  Sequence, based on SEQRES records:
  

  >6pwfC (C:)
  msgrgkggkvkgkaksrsnraglqfpvgrihrllrkgnyaervgagapvylaavmeylaa
  evlelagnaardnkktriiprhlqlairndeelnkllsgvtiaqggvlpniqavllpkkt
  ekka
  

  
  Sequence, based on observed residues (ATOM records):
  

  >6pwfC (C:)
  ksrsnraglqfpvgrihrllrkgnyaervgagapvylaavmeylaaevlelagnaardnk
  ktriiprhlqlairndeelnkllsgvtiaqggvlpniqavllpk
  

  
  
• Chain 'D':
  Sequence, based on SEQRES records:
  

  >6pwfD (D:)
  mppktsgkaakkagkaqknitktdkkkkrkrkesyaiyiykvlkqvhpdtgisskamsim
  nsfvndiferiaaeasrlahynkrstitsreiqtavrlllpgelakhavsegtkavtkyt
  ssk
  

  
  Sequence, based on observed residues (ATOM records):
  

  >6pwfD (D:)
  rkesyaiyiykvlkqvhpdtgisskamsimnsfvndiferiaaeasrlahynkrstitsr
  eiqtavrlllpgelakhavsegtkavtkytss
  

  
  
• Chain 'E':
  Sequence, based on SEQRES records:
  

  >6pwfE (E:)
  martkqtarkstggkaprkqlatkaarksapatggvkkphryrpgtvalreirryqkste
  llirklpfqrlvreiaqdfktdlrfqssavmalqeaseaylvglfedtnlcaihakrvti
  mpkdiqlarrirgera
  

  
  Sequence, based on observed residues (ATOM records):
  

  >6pwfE (E:)
  phryrpgtvalreirryqkstellirklpfqrlvreiaqdfktdlrfqssavmalqease
  aylvglfedtnlcaihakrvtimpkdiqlarrirge
  

  
  
• Chain 'F':
  Sequence, based on SEQRES records:
  

  >6pwfF (F:)
  mtgrgkggkglgkggakrhrkvlrdniqgitkpairrlarrggvkrisgliyeetrgvlk
  vflenvirdavtytehakrktvtamdvvyalkrqgrtlygfgg
  

  
  Sequence, based on observed residues (ATOM records):
  

  >6pwfF (F:)
  dniqgitkpairrlarrggvkrisgliyeetrgvlkvflenvirdavtytehakrktvta
  mdvvyalkrqgrtlygfgg
  

  
  
• Chain 'G':
  Sequence, based on SEQRES records:
  

  >6pwfG (G:)
  msgrgkggkvkgkaksrsnraglqfpvgrihrllrkgnyaervgagapvylaavmeylaa
  evlelagnaardnkktriiprhlqlairndeelnkllsgvtiaqggvlpniqavllpkkt
  ekka
  

  
  Sequence, based on observed residues (ATOM records):
  

  >6pwfG (G:)
  ksrsnraglqfpvgrihrllrkgnyaervgagapvylaavmeylaaevlelagnaardnk
  ktriiprhlqlairndeelnkllsgvtiaqggvlpniqavllpkk
  

  
  
• Chain 'H':
  Sequence, based on SEQRES records:
  

  >6pwfH (H:)
  mppktsgkaakkagkaqknitktdkkkkrkrkesyaiyiykvlkqvhpdtgisskamsim
  nsfvndiferiaaeasrlahynkrstitsreiqtavrlllpgelakhavsegtkavtkyt
  ssk
  

  
  Sequence, based on observed residues (ATOM records):
  

  >6pwfH (H:)
  rkrkesyaiyiykvlkqvhpdtgisskamsimnsfvndiferiaaeasrlahynkrstit
  sreiqtavrlllpgelakhavsegtkavtkytss
  

  
  
• Chain 'I':
  No sequence available.
  
  
• Chain 'J':
  No sequence available.
  
  
• Chain 'K':
  Sequence, based on SEQRES records:
  

  >6pwfK (K:)
  mahhhhhhghhhenlyfqgsssgkkhdrlgenkeddtlrrfryllgltdlfrhfietnpn
  pkireimaeidrqnaeeakkgssgggsaetvfresppfikgtmrdyqiaglnwlislhen
  gisgilademglgktlqtisflgylrhiqgitgphlvavpkstldnwkrefekwtpdvnv
  lvlqgakeerhqlindrlidedfdvcitsyemilrekahlkkfaweyiiideahriknee
  sslsqvirmfssrnrllitgtplqnnlhelwallnfllpdvfgdsdafdqwfrgqdrdqd
  qvvqqlhrvlrpfllrrvksdveksllpkkeinvyigmsemqvkwykkilekdidavnga
  ggkresktrllnivmqlrkccnhpylfegaepgppyttdehliynsgkmivldkllkrlq
  sqgsrvlifsqmsrlldiledycvfrgykycridggtahedriaaideynrpgsdkfifl
  lttragglginlttadtvilydsdwnpqadlqamdrahrigqtkqvvvyrfvtdnaieek
  vleraaqklrldqlviqqgraqiatkaaankeellsmiqhgaekvfqtkgafglmaekga
  nlddddidailkageertrelnakyeklgiddlqkftses
  

  
  Sequence, based on observed residues (ATOM records):
  

  >6pwfK (K:)
  fresppfikgtmrdyqiaglnwlislhengisgilademglgktlqtisflgylrhiqgi
  tgphlvavpkstldnwkrefekwtpdvnvlvlqgakeerhqlindrlidedfdvcitsye
  milrekahlkkfaweyiiideahrikneesslsqvirmfssrnrllitgtplqnnlhelw
  allnfllpdvfgdsdafdqwfrgqdrdqdqvvqqlhrvlrpfllrrvksdveksllpkke
  invyigmsemqvkwykkilekditrllnivmqlrkccnhpylfegaepgppyttdehliy
  nsgkmivldkllkrlqsqgsrvlifsqmsrlldiledycvfrgykycridggtahedria
  aideynrpgsdkfifllttragglginlttadtvilydsdwnpqadlqamdrahrigqtk
  qvvvyrfvtdnaieekvleraaqklrldqlviqq